Research Article
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Frequency of Microalbuminuria in Stages of Chronic Kidney Disease

Year 2026, Issue: Advanced Online Publication , 44 - 50
https://doi.org/10.56016/dahudermj.1886504
https://izlik.org/JA53JU56WH

Abstract

Objective: To investigate the frequency of microalbuminuria and associated risk factors across the stages of chronic kidney disease (CKD). 

Methods: This cross-sectional study included 200 patients aged 16-85 who applied to the Internal Medicine Outpatient Clinic between November 2009 and February 2010. Demographic data and blood pressure were recorded. Biochemical parameters, along with 24-hour urinary protein and albumin excretion, were measured. CKD staging was performed according to GFR calculated using the MDRD formula. 

Results: Of the patients, 64% were female. The most common etiology was undetermined (58%). Among identified causes, diabetes mellitus and hypertension were primary. As the CKD stage progressed, proteinuria and albuminuria levels increased significantly (p<0.001). The frequency of microalbuminuria was 23.1% in Stage 1 and reached 80% in Stage 5. Significant associations were found between CKD stages and blood pressure, urea, creatinine, potassium, calcium, hemoglobin, and CRP levels (p<0.05). Proteinuria and albuminuria showed a negative correlation with GFR and a positive correlation with CRP (p<0.001). 

Conclusion: Microalbuminuria appears from the early stages of CKD, and its frequency increases as the disease progresses. Hypertension and inflammation (elevated CRP) are independent risk factors associated with microalbuminuria. Screening CKD patients for microalbuminuria from the early stages is crucial for slowing disease progression.

Ethical Statement

Ethical approval for this study was obtained from the Ministry of Health, Diyarbakır Clinical Research Ethics Committee (Decision Date: December 28, 2009; Decision Number: 2009-91).

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There are 18 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Research Article
Authors

Mehmet Coşkun 0009-0008-2437-0512

Eşref Araç 0000-0001-6041-3817

Mehmet Emin Yılmaz

Submission Date February 15, 2026
Acceptance Date April 10, 2026
Early Pub Date April 17, 2026
DOI https://doi.org/10.56016/dahudermj.1886504
IZ https://izlik.org/JA53JU56WH
Published in Issue Year 2026 Issue: Advanced Online Publication

Cite

APA Coşkun, M., Araç, E., & Yılmaz, M. E. (2026). Frequency of Microalbuminuria in Stages of Chronic Kidney Disease. DAHUDER Medical Journal, Advanced Online Publication, 44-50. https://doi.org/10.56016/dahudermj.1886504
AMA 1.Coşkun M, Araç E, Yılmaz ME. Frequency of Microalbuminuria in Stages of Chronic Kidney Disease. DAHUDER MJ. 2026;(Advanced Online Publication):44-50. doi:10.56016/dahudermj.1886504
Chicago Coşkun, Mehmet, Eşref Araç, and Mehmet Emin Yılmaz. 2026. “Frequency of Microalbuminuria in Stages of Chronic Kidney Disease”. DAHUDER Medical Journal, no. Advanced Online Publication: 44-50. https://doi.org/10.56016/dahudermj.1886504.
EndNote Coşkun M, Araç E, Yılmaz ME (April 1, 2026) Frequency of Microalbuminuria in Stages of Chronic Kidney Disease. DAHUDER Medical Journal Advanced Online Publication 44–50.
IEEE [1]M. Coşkun, E. Araç, and M. E. Yılmaz, “Frequency of Microalbuminuria in Stages of Chronic Kidney Disease”, DAHUDER MJ, no. Advanced Online Publication, pp. 44–50, Apr. 2026, doi: 10.56016/dahudermj.1886504.
ISNAD Coşkun, Mehmet - Araç, Eşref - Yılmaz, Mehmet Emin. “Frequency of Microalbuminuria in Stages of Chronic Kidney Disease”. DAHUDER Medical Journal. Advanced Online Publication (April 1, 2026): 44-50. https://doi.org/10.56016/dahudermj.1886504.
JAMA 1.Coşkun M, Araç E, Yılmaz ME. Frequency of Microalbuminuria in Stages of Chronic Kidney Disease. DAHUDER MJ. 2026;:44–50.
MLA Coşkun, Mehmet, et al. “Frequency of Microalbuminuria in Stages of Chronic Kidney Disease”. DAHUDER Medical Journal, no. Advanced Online Publication, Apr. 2026, pp. 44-50, doi:10.56016/dahudermj.1886504.
Vancouver 1.Mehmet Coşkun, Eşref Araç, Mehmet Emin Yılmaz. Frequency of Microalbuminuria in Stages of Chronic Kidney Disease. DAHUDER MJ. 2026 Apr. 1;(Advanced Online Publication):44-50. doi:10.56016/dahudermj.1886504

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Volume with supplement

  • Nast A, Dreno B, Bettoli V, Degitz K, Erdmann R, Finlay AY, et al. European evidence-based (S3) guidelines for the treatment of acne. J Eur Acad Dermatol Venereol. 2012;26(Suppl 1):1–29.

Issue with supplement

  • Pagsberg AK. Schizophrenia spectrum and other psychotic disorders. Eur Child Adolesc Psychiatry. 2013;22(1 Suppl):S3–9.

Volume with part

  • Pilegaard H, Saltin B, Neufer PD. Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle. J Physiol. 2003;546(Pt 3):851–8.

Issue with part

  • Kamili S. Infectivity and vaccination efficacy studies in animal models of HBV S and pol gene mutants. Antivir Ther. 2010;15(3 Pt B):477–85.

Issue with no volume

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No volume or issue

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  • Adkinson NF. Drug allergy. In: Middleton E, Reed CE, Ellis EF, et al., editors. Allergy: principles and practice. 5th ed. St Louis (MO): Mosby; 2002. p. 1212–1224..

Conference proceedings

  • Qi E, Shen J, Dou R, editors. Proceedings of the 21st International Conference on Industrial Engineering and Engineering Management 2014; 2014 Nov 1–2; Zhuhai, China. Paris: Atlantis Press; 2015.
  • Halliday RB, Walter DE, Proctor HC, Norton RA, Colloff MJ, editors. Acarology: Proceedings of the 10th International Congress; 1998 Jul 5–10; Canberra, Australia. Melbourne: CSIRO Publishing; 2001.

Dissertation (Thesis)

  • Bansal Y. Building the theoretical foundations of deep learning: an empirical approach [dissertation]. Cambridge (MA): Harvard University Graduate School of Arts and Sciences; 2022.
  • Sürer S. From space to safety: flood mapping with Sentinel-1 SAR data for enhancing flood risk management in Ljungby Municipality [master’s thesis]. Lund (SE): Lund University; 2024 [Internet]. [cited 2025 Nov 22]. Available from: https://lup.lub.lu.se/student-papers/record/9158441
  • Patwary MM. Adoption of mobile banking applications: a study on young people [master’s thesis]. Eskişehir (TR): Anadolu University Graduate School of Social Sciences; 2017 [Internet]. [cited 2025 Nov 22]. Available from: https://doi.org/10.13140/RG.2.2.35579.49446

Poster(s)

  • Gianelli C, Kühne K, Rugani R. Numerical magnitude spatially biases unusual responses [poster]. Presented at: 20th Conference of the European Society for Cognitive Psychology (ESCoP); 2017 Sep 3–6; Potsdam, Germany.
  • Özge D, Vidinli D, Küntay A, Snedeker J. When you eat from the cake, is it all gone? Morphosyntax as a cue to partitivity [poster]. Presented at: 42nd Boston University Conference on Language Development (BUCLD 42); 2017 Nov 3–5; Boston, MA, USA.

Patent

  • Anders K, Fox JR, Harpur LS, Dunne J, inventors; International Business Machines Corp, assignee. Social media toxicity analysis. United States patent US 11,138,237. 2021 Oct 5.

Homepage/Website

  • Eurostat [Internet]. Luxembourg (LU): Statistical Office of the European Union; c1953– [cited 2025 Sep 27]. Available from: https://ec.europa.eu/eurostat

Proofreading

After DAHUDER MJ has prepared the layout of the article, it is sent to all authors for proofreading. All authors must view the pre-publication version of the article and approve its publication.

Multicenter clinical trials

DAHUDER MJ welcomes the submission of manuscripts reporting results of multicenter clinical trials. These manuscripts may be submitted with authorship in one of the following styles:

  • The name of a study group only (collective authorship)
  • The names of no more than five individuals and the name of a study group

In each case, one individual must serve as the corresponding author, and the names of all individuals specifically involved in the preparation of the manuscript should be listed under the heading Writing Committee following the Acknowledgments section. This should be followed by a list of investigators from each institution under the heading Study Group Investigators. Each author and each Writing Committee member must sign the Copyright Agreement and Author Acknowledgement Form.

Content responsibility
Content and scientific accuracy of all manuscripts, as well as of any electronic supplementary material, are the sole responsibility of the authors. No responsibility will be assumed by DAHUDER MJ for any legal claim arising from injury and/or damage to persons or property as a matter of product liability, negligence, or other circumstances; nor from any use or operation of any methods, products, instructions, or ideas contained in the published material. No test or procedure should be carried out unless the reader judges it to be safe. Independent verification of all diagnoses and drug dosages should be performed. Discussions, views, and recommendations regarding medical procedures, drug choices, and dosages are the sole responsibility of the authors.

Disclaimer
DAHUDER MJ does not accept or publish advertisements. Any mention of commercial products, if it occurs within scholarly content, does not imply endorsement by the journal.

Dahuder Medical Journal (Dahuder MJ) is an international, peer-reviewed academic journal dedicated to internal medicine, clinical medicine, and related health sciences. The journal publishes articles in English, operates a double-blind peer-review system, and adopts a continuous publication model, whereby accepted manuscripts are published online once all editorial and production procedures have been completed. Dahuder Medical Journal is committed to the highest standards of scientific quality, publication ethics, and academic integrity, and follows the principles and recommendations of COPE, ICMJE, the Declaration of Helsinki, and WAME.

Author Responsibilities

  • Authors must submit only original, unpublished manuscripts that are not simultaneously under review by another journal.
  • When an editor submits an article to a journal, their access is restricted until the peer-review process is complete. The editor cannot see any screens related to the article's progress.
  • For research involving human participants, animals, biological materials, personal data, or other sensitive content, all required ethics committee approvals and informed consent documents must be submitted completely and appropriately.
  • Authors are expected to avoid all forms of research and publication misconduct, including plagiarism, duplicate publication, redundant publication, data fabrication, data falsification, excessive textual overlap, and any other breaches of publication ethics.
  • The same study must not be submitted to or published in more than one journal or publication outlet.
  • All listed authors must satisfy the ICMJE authorship criteria. Honorary, guest, and ghost authorship are not acceptable.
  • Authors must provide valid ORCID IDs for all contributors.
  • Any actual or potential conflicts of interest must be declared clearly and transparently.
  • All sources of financial support, institutional assistance, and other contributions relevant to the study must be properly acknowledged.
  • Authors are fully responsible for the accuracy, reliability, and reproducibility of the data and content they submit.
  • All manuscripts submitted to the journal undergo a rigorous peer-review process involving at least two international reviewers with expertise in the relevant subject area. Reviewers are appointed by the Associate Editors and the Editor-in-Chief. In some cases, and for certain manuscript types, authors may be invited to suggest potential reviewers.
  • During peer review, manuscripts are assessed in terms of relevance to the journal’s scope, originality, readability, methodological and statistical soundness, and language quality.
  • At the conclusion of the evaluation process, a manuscript may be accepted, returned for minor revision, returned for major revision, or rejected.
  • A request for revision does not imply or guarantee final acceptance.
  • Authors must revise their manuscripts carefully, thoroughly, and within the requested timeframe, in accordance with the comments and recommendations of the editors and reviewers.
  • Rejected manuscripts are not reconsidered for review.
  • Final acceptance of a manuscript is also subject to compliance with all applicable legal and ethical requirements, including those relating to defamation, copyright infringement, plagiarism, and other relevant regulations.

Editor Responsibilities

  • Editors must assess submitted manuscripts fairly, independently, and objectively on academic grounds while preserving confidentiality throughout the editorial process.
  • Editorial decisions must be based on the originality of the work, its scientific contribution, methodological rigor, clarity of presentation, ethical compliance, and relevance to the aims and scope of the journal.
  • Editors must prevent conflicts of interest among authors, reviewers, editorial board members, and editorial staff, and they must refrain from handling manuscripts when an actual or potential conflict exists.
  • Editors are responsible for appointing competent, suitable, and impartial reviewers for each submission.
  • Editors must safeguard the integrity of the double-blind review process and ensure the confidentiality of authors, reviewers, and manuscript content at all stages of evaluation.
  • Editors should make every effort to ensure that submissions are processed within a reasonable time and that the editorial workflow proceeds in a consistent, careful, and transparent manner.
  • The Editor-in-Chief and Associate Editors hold full responsibility and authority regarding the acceptance or rejection of manuscripts.
  • Editors should not reverse a decision unless there is a serious, justified, and documented reason; similarly, decisions made by previous editors should not be changed without compelling grounds.
  • Editors must ensure that published material complies with internationally accepted ethical standards and, when necessary, should be adequately informed about the sources of research funding.
  • Editors are responsible for maintaining the scientific quality of the journal, the scholarly value of published content, and the integrity of the academic record.
  • Editors must take seriously all allegations of publication misconduct, ethical breach, or scientific unreliability, whether the manuscript is unpublished or already published, and they should make every reasonable effort to address such concerns appropriately.
  • When required, editors should publish corrections, clarifications, editorial notices, retractions, or errata in order to preserve the accuracy and reliability of the scholarly literature.
  • Editors should take into account the legitimate interests of both authors and readers while working to improve the journal’s academic and editorial standards.

Reviewer Responsibilities

  • Reviewers must treat all manuscripts assigned to them as confidential documents and must not share, copy, reproduce, or discuss them with third parties.
  • Review reports should be written in an objective, evidence-based, constructive, and respectful manner, without personal criticism of the authors.
  • Reviewers should accept invitations only for manuscripts that fall within their field of expertise, and they should decline review requests when they are unable to provide a competent and informed evaluation.
  • Reviewers must disclose any conflict of interest that could affect their neutrality, including financial, institutional, collaborative, or competitive relationships, and should withdraw from the process when appropriate.
  • Reviewer evaluations should focus on the manuscript’s scientific merit, originality, clarity, ethical appropriateness, and contribution to the field.
  • Reviewers should notify the editor of any important relevant references not cited by the authors, and of any substantial similarity or overlap with other published or submitted work known to them.
  • If a reviewer suspects plagiarism, duplicate submission, data manipulation, or any other ethical problem, the matter must be reported promptly to the Editor or Editor-in-Chief.
  • Reviewers are expected to complete their reports within the agreed time and to provide clear, justified, and understandable comments that support the editorial decision-making process.
  • Reviewers must not upload manuscript files or any part of manuscript content to artificial intelligence tools, AI-supported platforms, or any external system that may compromise confidentiality.

Plagiarism and Similarity Check Policy

  • All submissions to Dahuder MJ are screened for originality as part of the initial editorial assessment.
  • The journal maintains a strict policy against plagiarism, unethical text recycling, duplicate publication, and all other forms of academic misconduct.
  • Submitted manuscripts are evaluated using similarity-detection software during preliminary editorial review.
  • For Dahuder Medical Journal, the total similarity rate must not exceed 20%, excluding the reference list.
  • Similarity from any single source must not exceed 3%.
  • In certain cases, similarity found in the methodology section may be assessed separately at the discretion of the editors.
  • Manuscripts exceeding the journal’s similarity limits may be returned to the authors for revision, correction, or detailed explanation.
  • Authors bear full responsibility for the originality of their work and for the correct citation and acknowledgment of all sources consulted.
  • Authors are expected to review and comply with the journal’s full plagiarism and similarity policy before submission.

Research Ethics

  • All research involving human participants must have received prior approval from an appropriate ethics committee.
  • Research involving human subjects must be conducted in accordance with the principles of the Declaration of Helsinki.
  • Where relevant, the manuscript must clearly state that informed consent was obtained from the participants.
  • For clinical research, registration details and all relevant ethical approvals must be reported.
  • Studies involving animals must be carried out in accordance with internationally accepted principles of animal welfare and research ethics.
  • Authors must explicitly state that the study was conducted and reported in compliance with ethical standards.

Data Transparency

  • Authors must be prepared to provide raw data, supporting materials, or further explanations to the editors upon request for verification purposes.
  • Research data must be presented accurately, comprehensively, and transparently.
  • Data fabrication, falsification, selective reporting, and related practices are regarded as serious violations of scientific ethics.

Conflict of Interest

  • Authors, reviewers, and editors must disclose any financial, personal, institutional, or professional conflicts of interest that could influence the research, review, or editorial decision-making process.
  • Any potential conflict of interest must be managed in a manner that preserves transparency and trust in the editorial and peer-review process.
  • Individuals who have a conflict of interest must not take part in the relevant review or editorial decisions in order to protect impartiality.

Artificial Intelligence (AI) Use Policy

  • Authors must clearly disclose any artificial intelligence tools used during manuscript preparation. Such disclosure should appear in the Methods section, Acknowledgments, or another appropriate part of the manuscript, and should specify the name of the tool, the version when applicable, and the purpose for which it was used.
  • AI tools may be used only for limited technical assistance, such as language editing, spelling and grammar correction, formatting support, reference organization, coding assistance, data visualization, and statistical or computational support.
  • The use of AI must not undermine the originality, scientific validity, accuracy, or reliability of the manuscript.
  • AI tools must not be used to generate scientific arguments, original interpretations, hypotheses, results, discussions, or scholarly conclusions.
  • AI must not be used to fabricate, falsify, manipulate, distort, or invent data, images, findings, references, or citations.
  • AI systems cannot replace the researcher’s scientific reasoning, academic judgment, or ethical responsibility.
  • AI tools cannot be credited as authors because they do not meet authorship criteria and cannot assume responsibility for the work.
  • The authors remain fully responsible for the accuracy, originality, and ethical compliance of the entire manuscript content.
  • Editors and reviewers may use AI only for limited technical purposes that do not compromise confidentiality and that remain fully consistent with the journal’s policy. AI must not be used for editorial decision-making, reviewer report writing, or as a substitute for expert human evaluation.
  • Editors and reviewers must not upload manuscripts, supplementary files, figures, data, or peer-review correspondence to external AI systems.

Retraction

  • An article may be retracted in the following circumstances:
  • Confirmed plagiarism, data fabrication, or data falsification,
  • Confirmed duplicate publication,
  • Serious errors that invalidate or substantially undermine the conclusions of the study,
  • Ethical violations that compromise the reliability and integrity of the published work.
  • Retracted articles remain accessible in the public record in order to preserve the transparency of scholarly communication. Such articles are clearly identified with a “RETRACTED” watermark and are accompanied by a formal retraction notice explaining the reason.

Withdrawal

  • Requests for withdrawal must be submitted with a formal written explanation.
  • Withdrawal requests submitted after the peer-review process has begun, without a valid and convincing justification, may be regarded as unethical publishing conduct.

Corrections

  • Corrections, including corrigenda, errata, and addenda, are issued when minor errors or omissions do not invalidate the overall findings of the study but nevertheless require clarification or amendment.

Handling of Ethical Misconduct

  • Allegations of ethical misconduct or concerns regarding the scientific reliability of a submission or publication are examined carefully and confidentially by the editorial office.
  • When necessary, the editor initiates an investigation in accordance with COPE and ICMJE guidance and may request explanations, official documents, or supporting evidence from the authors.
  • If the suspicion of misconduct is serious, the editor may consider notifying the relevant institution of the authors and, where appropriate, the relevant funding organizations.
  • During an ongoing investigation, the editor may publish an expression of concern when there is substantial doubt about the integrity of the manuscript or article.
  • If misconduct is confirmed, the manuscript may be rejected; if the article has already been published, a correction, expression of concern, or retraction may be issued.
  • Retractions and expressions of concern are published in a clear, reasoned, and visible manner and are linked to the original article.
  • Throughout this process, the journal maintains editorial impartiality, procedural confidentiality, and the integrity of the scholarly record.

Official Editorial Communication Address

  • All formal correspondence concerning the editorial and peer-review process shall be conducted through the journal’s official communication address: selcukyaylaci@sakarya.edu.tr
  • Such correspondence may include, but is not limited to, initial editorial screening, requests for clarification, authorship verification, ethical inquiries, notifications concerning suspected misconduct, and decisions regarding revision, acceptance, rejection, or withdrawal.
  • Authors are responsible for monitoring this address regularly and for responding in a timely manner so that delays in the editorial process may be avoided.
  • All messages sent to or received from this address constitute part of the journal’s official editorial record.
  • Failure to respond within a reasonable period may disrupt the editorial workflow and may result in administrative action.

• DAHUDER Medical Journal does not charge any fees for article submission, peer review, editorial processing, page layout, or publication (including page or color charges).
• DAHUDER MJ does not pay any fees or honoraria to authors, reviewers, editors, or editorial board members.
• All articles are free to read and download.
• DAHUDER MJ is an open-access journal and does not require any subscription fees.
• DAHUDER MJ is a signatory to the Budapest Open Access Initiative (BOAI) and adheres to the Open Access principles set out in this initiative.
• All articles are preserved via the LOCKSS (Lots Of Copies Keep Stuff Safe) system through TÜBİTAK ULAKBİM DergiPark.
• In line with its publication policy, the journal does not accept announcements, advertisements, sponsorships, or similar content.
• The journal does not offer a reprint service for professional-quality reproductions of articles.
• All expenses of DAHUDER MJ are covered by the publisher.

Editorial Board

Toxicology, Cardiology, ​Internal Diseases, Nanotoxicology, Health and Safety

Assistant Editor

​Internal Diseases

Editorial Board_eski

Cellular Interactions, Proteomics and Intermolecular Interactions, Medical Pharmacology, Biologically Active Molecules, Biomolecular Modelling and Design, Cheminformatics and Quantitative Structure-Activity Relationships
Public Health (Other)
Respiratory Diseases, Endocrinology, Geriatrics and Gerontology, ​Internal Diseases, Rural Clinical Health, Clinimetrics, Intensive Care, Clinical Sciences (Other)
Immunology (Other), Haematology, Endocrinology, ​Internal Diseases, Clinical Oncology, Rheumatology and Arthritis
​Internal Diseases
​Internal Diseases
​Internal Diseases
​Internal Diseases, Medical Education
​Internal Diseases
​Internal Diseases
​Internal Diseases
​Internal Diseases
​Internal Diseases
​Internal Diseases, Oncology and Carcinogenesis
​Internal Diseases
Pharmaceutical Analytical Chemistry, Pharmaceutical Chemistry
Family Medicine
Microbiology (Other), Basic Pharmacology

Statistics Editor

Machine Vision , ​Internal Diseases

 

INDEXING & ABSTRACTING & ARCHIVING

 

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