Successful Treatment of Thyroid Storm with Therapeutic Plasmapheresis In a Geriatric Patient

Yıl 2021, Cilt: 1 Sayı: 1, 30 - 34, 29.10.2021

Mehmet Kök Seyit Uyar Ersin Kapağan Işılay Kalan Sarı Firdevs Pelin Eskin Miyase Sayal

Öz

Thyroid storm is a rare and fatal condition characterized by severe clinical manifestations of thyrotoxicosis. In geriatric patients, care should be taken in the follow-up of thyrotoxicosis due to comorbid diseases. Therapeutic plasmapheresis is an apheresis method that separates plasma from the components and removes the harmfull substances from the blood. This method may clear thyroid hormones from the blood and is recommended as an alternative option in the treatment of thyroid storm. In this case, we aimed to present an old patient with known alzheimer's disease and multinodular goiter induced thyrotoxicosis. The patient who could not get the first line treatments completely due to complications and were finally diagnosed with thyroid storm, recovered with therapeutic plasmapheresis treatment without any problem and was discharged.

Anahtar Kelimeler

Lithium, Thyroid storm, Plasmapheresis

Kaynakça

• Reference1- Galindo RJ, Hurtado CR, Pasquel FJ, Tome RG , Peng L, Umpierrez GE. National Trends in Incidence, Mortality, and Clinical Outcomes of Patients Hospitalized for Thyrotoxicosis With and Without Thyroid Storm in the United States, 2004-2013. Thyroid. 2019;29:36-43. doi: 10.1089/thy.2018.0275
• Reference2- Burch HB, Wartofsky L. Life-threatening thyrotoxicosis. Thyroid storm. Endocrinol Metab Clin North Am. 1993;22:263.
• Reference3- Schwartz J, Winters JL, Padmanabhan A, Balogun RA, Delaney M, Linenberger ML et al. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach From the Writing Committee of the American Society for Apheresis: The Sixth Special Issue. J Clin Apher. 2013;28(3):145-284. doi:10.1002/jca.21276
• Reference4- Daga Ruiz D, Fonseca San Miguel F, González de Molina FJ, Úbeda-Iglesias A, Navas Pérez A, Jannone Forés R. Plasmapheresis and other extracorporeal filtration techniques in critical patients. Med Intensiva. 2017;41(3):174-187. doi: 10.1016/j.medin.2016.10.005
• Reference5- Tengku Ibrahim TZ, Thambiah SC, Samsudin IN, Nasuruddin AN, Zakariaet MH. Thyroid storm: Is there a role for thyroid function test? Malays J Pathol. 2019;41(3):355-358.
• Reference6- Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia LA et al. 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis. Thyroid. 2016;26:1343-1421. doiI: 10.1089/thy.2016.0229
• Reference7- Altun İK, Kılıç N, Yıldızoğlu E, Atagün Mİ. Lityuma Bağlı Yan Etkiler ve Nörotoksisite: Lityum Nörotoksisitesi Demir Birikimiyle İlgili Olabilir Mi? Psikiyatride Güncel Yaklaşımlar. 2019;11(2):141-153. doi:10.18863/pgy.384067
• Reference8- Padmanabhan A, Connelly-Smith L, Aqui N, Balogun RA, Klingel R, Meyer E, et al. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice - Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue. J Clin Apher. 2019;34(3):171-354. doi: 10.1002/jca.21705
• Reference9- Garla V, Kovvuru K, Ahuja S, Palabindala V, Malhotra B, Abdul Salim S. Severe Hyperthyroidism Complicated by Agranulocytosis Treated With Therapeutic Plasma Exchange: Case Report and Review of the Literature. Case Rep Endocrinol 2018. doi: 10.1155/2018/4135940