Öz
Tumor necrosis factor-alpha (TNF-α), which is produced by macrophages and activated T lymphocyte cells, plays a main role in inducing further stimulation of other inflammatory cells. Anti-TNF-α drugs are used for induction and preservation of remission in patients with Ankylosing spondylitis. Etanercept, which is one of the most used Anti-TNF-α drugs, has side effects such as cytopenia but isolated thrombocytopenia is an uncommon adverse event. We report the case of a 40-year-old man diagnosed with Ankylosing spondylitis who developed Etanercept-induced isolated thrombocytopenia.
Anahtar Kelimeler
Thrombocytopenia Ankylosing Spondylitis adverse effect biological agents
Kaynakça
- Referans1. Khanna D, Mcmahon M, Furst DE. Safety Of Tumor Necrosis Factor alpha Antagonists Drug Saf 2004;27(5):307–24.
- Referans2. Keystone E. Safety Of Biologic Therapies—An Update. J Rheumatol 2005;32:8–12.
- Referans3. Cush JJ. Safety Of New Biologic Therapies İn Rheumatoid Arthritis. Bullet Rheum Dis 2003–04;52.
- Referans4. Malgarini RB, Pimpinella G. Etanercept And Methotrexate İn Rheumatoid Arthritis. Lancet 2004; 363(9422):1733.
- Referans5. Rheum Dis Clin North Am 2001;27:427–4
- Referans6. Selby LA, Hess D, Shashidar H, De Villiers WJ, Selby LA. Crohn's Disease, İnfliximab And İdiopathic Thrombocytopenic Purpura.Inflamm Bowel Dis Sep 2004;10(5):698–700
- Referans7. S. K. Pathare, C. Heycock, J. Hamılton Tnf Blocker-İnduced Thrombocytopenia Rheumatology 2006;45: 1313–1314.
- Referans8. M.J. Casanova A,⁎, M. Chaparro A, C, S. Martínez B, I. Vicuña B, J.P. Gisbert A, C Severe Adalimumab-İnduced Thrombocytopenia İn A Patient ith Crohn's Disease Journal Of Crohn's And Colitis (2012) 6, 1034–1037
- Referans9. Valderílio Feijó Azevedo1, Marília Barreto Gameiro Silva2, Débora Karine Marinello3, Felipe Dunin Dos Santos4, Guilherme Barreto Gameiro Silva4 Leukopenia And Thrombocytopenia İnduced By Etanercept: Two Case Reports And Literature Review Rev Bras Reumatol 2011;52(1):107-112).
Öz
Kaynakça
- Referans1. Khanna D, Mcmahon M, Furst DE. Safety Of Tumor Necrosis Factor alpha Antagonists Drug Saf 2004;27(5):307–24.
- Referans2. Keystone E. Safety Of Biologic Therapies—An Update. J Rheumatol 2005;32:8–12.
- Referans3. Cush JJ. Safety Of New Biologic Therapies İn Rheumatoid Arthritis. Bullet Rheum Dis 2003–04;52.
- Referans4. Malgarini RB, Pimpinella G. Etanercept And Methotrexate İn Rheumatoid Arthritis. Lancet 2004; 363(9422):1733.
- Referans5. Rheum Dis Clin North Am 2001;27:427–4
- Referans6. Selby LA, Hess D, Shashidar H, De Villiers WJ, Selby LA. Crohn's Disease, İnfliximab And İdiopathic Thrombocytopenic Purpura.Inflamm Bowel Dis Sep 2004;10(5):698–700
- Referans7. S. K. Pathare, C. Heycock, J. Hamılton Tnf Blocker-İnduced Thrombocytopenia Rheumatology 2006;45: 1313–1314.
- Referans8. M.J. Casanova A,⁎, M. Chaparro A, C, S. Martínez B, I. Vicuña B, J.P. Gisbert A, C Severe Adalimumab-İnduced Thrombocytopenia İn A Patient ith Crohn's Disease Journal Of Crohn's And Colitis (2012) 6, 1034–1037
- Referans9. Valderílio Feijó Azevedo1, Marília Barreto Gameiro Silva2, Débora Karine Marinello3, Felipe Dunin Dos Santos4, Guilherme Barreto Gameiro Silva4 Leukopenia And Thrombocytopenia İnduced By Etanercept: Two Case Reports And Literature Review Rev Bras Reumatol 2011;52(1):107-112).
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | İç Hastalıkları |
| Bölüm | Case Reports |
| Yazarlar | |
| Yayımlanma Tarihi | 29 Ocak 2022 |
| Gönderilme Tarihi | 30 Aralık 2021 |
| Yayımlandığı Sayı | Yıl 2022 Cilt: 2 Sayı: 1 |
