Research Article

Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy?

Volume: 40 Number: 2 April 29, 2026

Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy?

Abstract

Background: Hemorrhoidal disease is a common anorectal condition affecting approximately 40% of the population. Routine histopathological examination of excised hemorrhoidal tissue is debated, with some studies recommending it for all cases, while others suggest it only when clinical suspicion is present. This study aims to evaluate the necessity of routine histopathological examination following hemorrhoidectomy. Methods: A retrospective analysis was conducted on 1227 patients who underwent hemorrhoidectomy at Van Training and Research Hospital and Amasya University Sabuncuoglu Serefeddin Training and Research Hospital between January 1, 2015, and December 31, 2024. Patient data, including age, gender, and pathology results, were reviewed. Results: Of the 1227 patients, 863 (70.3%) were male, with a mean age of 41.3 years. Pathological examination revealed no malignancy; however, 1 case of tubulovillous adenoma and 1 case of high-grade squamous intraepithelial lesion (AIN 3) were detected. A total of 1211 patients had hemorrhoids, while other benign and premalignant lesions were also found incidentally. Discussion: Routine histopathological examination after hemorrhoidectomy is controversial, with studies indicating low malignancy rates. Some experts advocate for examination in high-risk patients or when clinical suspicion is raised. This study supports the need for histopathological examination in such cases, although further research is required to establish clear guidelines. Routine histopathological examination after hemorrhoidectomy may be unnecessary for most patients, but should be performed in cases with clinical suspicion or specific risk factors to enhance cost-effectiveness and reduce unnecessary interventions.

Keywords

References

  1. 1. Talaie R, Torkian P, Dooghaie Moghadam A, Tradi F, Vidal V, Sapoval M, et al. Hemorrhoid embolization: A review of current evidences. Diagn Interv Imaging. 2022;103(1):3-11.
  2. 2. Ray-Offor E, Amadi S. Hemorrhoidal disease: Predilection sites, pattern of presentation, and treatment. Ann Afr Med. 2019;18(1):12-16.
  3. 3. Mott T, Latimer K, Edwards C. Hemorrhoids: Diagnosis and treatment options. American Family Physician. 2018; 97(3):172-179.
  4. 4. Higuero T, Abramowitz L, Castinel A, Fathallah N, Hemery P, Laclotte Duhoux C, et al. Guidelines for the treatment of hemorrhoids. J Visceral Surg. 2016;153(3): 213-218.
  5. 5. Men, V, Kaur D, Bahl P, Jin J, Hill A. Is routine histopathological analysis of hemorrhoidectomy specimens necessary? A systematic review and meta-analysis. World J Surg. 2024;48(8):1981-1989.
  6. 6. Luca, N, Valentina A, Federico S, Renato P. Unexpected anal squamous cells carcinoma after open hemorrhoidectomy. Case Rep Surg. 2015;2015: 616274.
  7. 7. He X, Huang J, Yao J, Chen Z, Lian L, Li S, et al. Routine histopathologic examination of "benign" anal lesions: is it necessary? Surg Today. 2015;45(4):416-421.
  8. 8. Bauer P, Fléjou JF, Etienney I; Proctological Prospective Diaconesses Group. Prospective Single-Center Observational Study of Routine Histopathologic Evaluation of Macroscopically Normal Hemorrhoidectomy and Fissurectomy Specimens in Search of Anal Intraepithelial Neoplasia. Dis Colon Rectum. 2015;58(7):692-697.

Details

Primary Language

English

Subjects

Clinical Sciences (Other)

Journal Section

Research Article

Early Pub Date

April 29, 2026

Publication Date

April 29, 2026

Submission Date

July 4, 2025

Acceptance Date

September 18, 2025

Published in Issue

Year 2026 Volume: 40 Number: 2

APA
Doğan, İ., Canlıkarakaya, F., & Ocaklı, S. (2026). Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy? Developments and Experiments in Health and Medicine, 40(2), 178-183. https://doi.org/10.18614/dehm.1735281
AMA
1.Doğan İ, Canlıkarakaya F, Ocaklı S. Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy? Dev Exp Health Med. 2026;40(2):178-183. doi:10.18614/dehm.1735281
Chicago
Doğan, İbrahim, Fırat Canlıkarakaya, and Serhat Ocaklı. 2026. “Histopathological Analysis After Hemorrhoidectomy: A Necessity or a Redundancy?”. Developments and Experiments in Health and Medicine 40 (2): 178-83. https://doi.org/10.18614/dehm.1735281.
EndNote
Doğan İ, Canlıkarakaya F, Ocaklı S (April 1, 2026) Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy? Developments and Experiments in Health and Medicine 40 2 178–183.
IEEE
[1]İ. Doğan, F. Canlıkarakaya, and S. Ocaklı, “Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy?”, Dev Exp Health Med, vol. 40, no. 2, pp. 178–183, Apr. 2026, doi: 10.18614/dehm.1735281.
ISNAD
Doğan, İbrahim - Canlıkarakaya, Fırat - Ocaklı, Serhat. “Histopathological Analysis After Hemorrhoidectomy: A Necessity or a Redundancy?”. Developments and Experiments in Health and Medicine 40/2 (April 1, 2026): 178-183. https://doi.org/10.18614/dehm.1735281.
JAMA
1.Doğan İ, Canlıkarakaya F, Ocaklı S. Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy? Dev Exp Health Med. 2026;40:178–183.
MLA
Doğan, İbrahim, et al. “Histopathological Analysis After Hemorrhoidectomy: A Necessity or a Redundancy?”. Developments and Experiments in Health and Medicine, vol. 40, no. 2, Apr. 2026, pp. 178-83, doi:10.18614/dehm.1735281.
Vancouver
1.İbrahim Doğan, Fırat Canlıkarakaya, Serhat Ocaklı. Histopathological analysis after hemorrhoidectomy: A necessity or a redundancy? Dev Exp Health Med. 2026 Apr. 1;40(2):178-83. doi:10.18614/dehm.1735281