BibTex RIS Kaynak Göster

The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization

Yıl 2015, Cilt: 42 Sayı: 4, 472 - 479, 08.01.2016

Öz

Objective: The aim of this study is to evaluate the relationship between endometrial and sub-endometrial blood flow and implantation rate in patients whose undergone in vitro fertilization.

Methods: A prospective study was conducted. Long protocol and antagonist regimens were administered to the patients. Endometrial and sub-endometrial blood flow was evaluated by using 3 dimensional Doppler ultrasonography on the day of oocyt retrieval measurement. For comparison pregnant and non-pregnant women in terms of endometrial and sub-endometrial blood flow, t test was used. The p value was considered statistically meaningful as <0.05.

Results: Endometrial and sub-endometrial blood flow was not different between pregnant and non-pregnant women in both groups (p>0.05). In long protocol group, the number of embryo was greater in pregnant women than non-pregnant women (p=0.012). The number of transferred embryo increased pregnancy rate almost 3.5 fold (p=0.002).

Conclusion: The endometrial and subendometrial blood flow is not reliable factor in prediction pregnancy or implantation.

Key words: Doppler ultrasonography, in vitro fertilization, pregnant women

Kaynakça

  • Ng EH, Chan CC, Tang OS, Ho PC. Comparison of 2-dimensional,
  • -dimensional, and vascular ultrasonographic parameters for endometrial receptivity between 2 consecutive stimulated in vitro fertilization cycles. J Ultrasound Med. 2007;26:931-939.
  • Bahar L, Kahraman S, Akkus A, Baykal T. Fine structure and
  • immune histochemical evaluation of endometrium in fertile and infertile women with implantation failure. Dicle Medical Journal 2012;39:269-295.
  • Gannon BJ, Carati CJ, Verco CJ. Endometrial perfusion across the normal human menstrual cycle assessed by laser Doppler fluxmetry. Hum Reprod. 1997;12:132-139.
  • Raine-Fenning NJ, Campbell BK, Clewes JS, Kendall NR, Johnson IR. The reliability of virtual organ computer-aided analysis (VOCAL) for the semi quantification of ovarian, endometrial and subendometrial perfusion. Ultrasound Obstet Gynecol 2003;22:633-639.
  • Chien LW, Au HK, Chen PL, et al. Assessment of uterine receptivity by the endometrial-subendometrial blood flow distribution pattern in women undergoing in vitro fertilization-embryo transfer. Fertil Steril 2002;78:245-251.
  • Hsieh YY, Chang FC, Tsai HD. Doppler evaluation of the uterine and spiral arteries from different sampling sites and phases of the menstrual cycle during controlled ovarian hyper-stimulation.
  • Ultrasound Obstet. Gynecol 200;16:192-196.
  • Raine-Fenning N. The role of three-dimensional ultrasound in assisted reproduction treatment. Ultrasound Obstet Gynecol 2004;23:317-322.
  • Ng EH, Chan CC, Tang OS, et al. The role of endometrial and sub-endometrial blood flows measured by three-dimensional power Doppler ultrasound in the prediction of pregnancy during IVF treatment. Hum Reprod 2006;21:164-170.
  • Guerriero S, Ajossa S, Lai MP, et al. Clinical applications of colour Doppler energy imaging in the female reproductive tract and pregnancy. Hum Reprod Update 1999;5:515-529.
  • Zaidi J, Campbell S, Pittrof FR and Tan SL. Endometrial
  • thickness morphology, vascular penetration and velocimetry in predicting implantation in an IVF program. Ultrasound Obstet Gynecol 1995;6:191-198.
  • Ng EHY, Chan CCW, Tang OS, et al. Endometrial and subendometrial blood flow measured during early luteal phase
  • by three dimensional Power Doppler ultrasound in excessive ovarian responders. Hum Reprod 2004;19:924-931.
  • Merce LT, Barco MJ, Bau S, Troyano J. Are endometrial parameters by three-dimensional ultrasound and power Doppler
  • angiography related to in vitro fertilization/embryo transfer outcome? Fertil Steril 2008;89:111.
  • Achache H, Revel A. Endometrial receptivity markers, the
  • journey to successful embryo implantation. Hum Reprod Update 2006;12:731.
  • Kim A, Jung H, Choi WJ, et al. Detection of endometrial and sub-endometrial vasculature on the day of embryo transfer and prediction of pregnancy during fresh in vitro fertilization cycles. Taiwan J Obstet Gynecol 2014;53:360-365.
  • Battaglia C, Artini PG, Giulini S, et al. Colour Doppler changes and thromboxane production after ovarian stimulation with gonadotrophin- releasing hormone agonist. Hum Reprod 1997;12:2477-2482.
  • Kupesic S, Bekavac I, Bjelos D, Kurjak A. Assessment of endometrial receptivity by transvaginal color Doppler and three-dimensional power Doppler ultrasonography in patients undergoing in vitro fertilization procedures. J Ultrasound Med 2001;20:125-134.
  • Merce LT, Barco MJ, Bau S, Troyano J. Are endometrial parameters by three-dimensional ultrasound and power Doppler
  • angiography related to in vitro fertilization/embryo transfer outcome? Fertil Steril 2008;89:111-117.
  • Wu HM, Chiang CH, Huang HY, et al. Detection of the subendometrial vascularization flow index by three-dimensional
  • ultrasound may be useful for predicting the pregnancy rate for patients undergoing in vitro fertilization-embryo transfer. Fertil Steril 2003;79:507-511.
  • Dechaud H, Bessueille E, Bousquet PJ, et al. Optimal timing of ultrasonographic and Doppler evaluation of uterine receptivity to implantation.Reprod Biomed Online.2008;16:368-375.
  • Fraser IS, Mc Carron G, Hutton B, Macey D. Endometrial blood flow measured by xenon 133 clearance in women with normal menstrual cycles and dysfunctional uterine bleeding. Am J Obstet Gynecol 1987;156:158-166.
  • Nandi A, Martins WP, Jayaprakasan K, et al. Assessment of endometrial and subendometrial blood flow in women undergoing frozen embryo transfer cycles. Reprod Biomed Online. 2014;28:343-351.
  • Spandorfer SD, Arrendondo-Soberon F, Loret de Mola JR, Feinberg RF. Reliability of intraobserver and interobserver sonographic endometrial stripe thickness measurements. Fertil Steril 1998;70:152-154.
  • Raine-Fenning NJ, Clewes JS, Kendall NR, et al. The inter observer reliability and validity of volume calculation from three-dimensional ultrasound data sets in the in vitro setting. Ultrasound Obstet Gynecol 2003;21:283-291
Toplam 32 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Yazıları
Yazarlar

Yusuf Çakmak Bu kişi benim

Mehmet Şentürk

Mehmet Budak Bu kişi benim

Yayımlanma Tarihi 8 Ocak 2016
Gönderilme Tarihi 8 Ocak 2016
Yayımlandığı Sayı Yıl 2015 Cilt: 42 Sayı: 4

Kaynak Göster

APA Çakmak, Y., Şentürk, M., & Budak, M. (2016). The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization. Dicle Medical Journal, 42(4), 472-479. https://doi.org/10.5798/diclemedj.0921.2015.04.0611
AMA Çakmak Y, Şentürk M, Budak M. The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization. diclemedj. Ocak 2016;42(4):472-479. doi:10.5798/diclemedj.0921.2015.04.0611
Chicago Çakmak, Yusuf, Mehmet Şentürk, ve Mehmet Budak. “The Predictive Value of Three-Dimensional Doppler Ultrasonography in Determining Implantation in Patients Underwent in Vitro Fertilization”. Dicle Medical Journal 42, sy. 4 (Ocak 2016): 472-79. https://doi.org/10.5798/diclemedj.0921.2015.04.0611.
EndNote Çakmak Y, Şentürk M, Budak M (01 Ocak 2016) The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization. Dicle Medical Journal 42 4 472–479.
IEEE Y. Çakmak, M. Şentürk, ve M. Budak, “The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization”, diclemedj, c. 42, sy. 4, ss. 472–479, 2016, doi: 10.5798/diclemedj.0921.2015.04.0611.
ISNAD Çakmak, Yusuf vd. “The Predictive Value of Three-Dimensional Doppler Ultrasonography in Determining Implantation in Patients Underwent in Vitro Fertilization”. Dicle Medical Journal 42/4 (Ocak 2016), 472-479. https://doi.org/10.5798/diclemedj.0921.2015.04.0611.
JAMA Çakmak Y, Şentürk M, Budak M. The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization. diclemedj. 2016;42:472–479.
MLA Çakmak, Yusuf vd. “The Predictive Value of Three-Dimensional Doppler Ultrasonography in Determining Implantation in Patients Underwent in Vitro Fertilization”. Dicle Medical Journal, c. 42, sy. 4, 2016, ss. 472-9, doi:10.5798/diclemedj.0921.2015.04.0611.
Vancouver Çakmak Y, Şentürk M, Budak M. The predictive value of three-dimensional Doppler ultrasonography in determining implantation in patients underwent in vitro fertilization. diclemedj. 2016;42(4):472-9.