EN
TR
Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy
Abstract
Aim: Older adults often face significant issues related to functionality, balance, and fall risk. This study aimed to investigate balance, kinesiophobia, and mobility in older adults exposed to polypharmacy.
Material and Methods: This cross-sectional study included a total of 75 individuals aged 65 years and over who were exposed to polypharmacy and presented to a university hospital between November 2023 and March 2024, and with a standardized mini-mental test (SMMT) score of 25 and above. Data were collected using the patient introduction and medication use questionnaire, the Berg balance scale (BBS), the Tampa kinesiophobia scale (TKS), and the timed up and go (TUG) test.
Results: Individuals who completed the TUG test within 0-1414 seconds exhibited higher BBS scores when compared to those who completed the test in more than 14 seconds (p=0.001), while the TKS scores were lower (p=0.001). Furthermore, it was observed that individuals with a history of falls had higher TKS (p=0.001) and TUG test (p=0.001) scores than those without a history of falls. Additionally, the number of chronic diseases showed a negative correlation with BBS scores (rs=-0.319, p=0.005), while exhibiting a positive correlation with TKS scores (rs=0.263, p=0.023) and TUG test (rs=0.316, p=0.006) durations.
Conclusion: The findings of the study indicate that polypharmacy has a deleterious effect on balance and mobility in older adults. It is imperative to evaluate the suitability of the prescribed medications and to take into account the patient's current medications prior to the initiation of new medications.
Keywords
References
- World Health Organization. Medication safety in polypharmacy. Technical report. Geneva: World Health Organization; 2019.
- Midão L, Giardini A, Menditto E, Kardas P, Costa E. Polypharmacy prevalence among older adults based on the survey of health, ageing and retirement in Europe. Arch Gerontol Geriatr. 2018;78:213-20.
- Nicholson K, Liu W, Fitzpatrick D, Hardacre KA, Roberts S, Salerno J, et al. Prevalence of multimorbidity and polypharmacy among adults and older adults: a systematic review. Lancet Healthy Longev. 2024;5(4):e287-96.
- Aydos TR, Emre Aydingöz S, Lux KM, Efe OE, İşli F, Aksoy M, et al. Polypharmacy prevalence among geriatric patients in primary healthcare settings across Turkey: A cross-sectional analysis through the nationwide prescription information system. Turk J Geriatr. 2020;23(2):169-79.
- Pazan F, Wehling M. Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences. Eur Geriatr Med. 2021;12(3):443-52.
- Canio WC. Polypharmacy in older adults. Clin Geriatr Med. 2022;38(4):621-5.
- Mouazer A, Tsopra R, Sedki K, Letord C, Lamy JB. Decision-support systems for managing polypharmacy in the elderly: A scoping review. J Biomed Inform. 2022;130:104074.
- Pereira KG, Peres MA, Iop D, Boing AC, Boing AF, Aziz M, et al. Polypharmacy among the elderly: a population-based study. Rev Bras Epidemiol. 2017;20(2):335-44.
Details
Primary Language
English
Subjects
Geriatrics and Gerontology
Journal Section
Research Article
Early Pub Date
June 9, 2025
Publication Date
August 30, 2025
Submission Date
November 15, 2024
Acceptance Date
May 6, 2025
Published in Issue
Year 2025 Volume: 27 Number: 2
APA
Salkın, Y., Kazak Saltı, A., Erden Ertürk, S., & Altınkaya, P. M. (2025). Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy. Duzce Medical Journal, 27(2), 123-129. https://doi.org/10.18678/dtfd.1585896
AMA
1.Salkın Y, Kazak Saltı A, Erden Ertürk S, Altınkaya PM. Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy. Duzce Med J. 2025;27(2):123-129. doi:10.18678/dtfd.1585896
Chicago
Salkın, Yasemin, Aysun Kazak Saltı, Sema Erden Ertürk, and Pınar Müge Altınkaya. 2025. “Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy”. Duzce Medical Journal 27 (2): 123-29. https://doi.org/10.18678/dtfd.1585896.
EndNote
Salkın Y, Kazak Saltı A, Erden Ertürk S, Altınkaya PM (August 1, 2025) Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy. Duzce Medical Journal 27 2 123–129.
IEEE
[1]Y. Salkın, A. Kazak Saltı, S. Erden Ertürk, and P. M. Altınkaya, “Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy”, Duzce Med J, vol. 27, no. 2, pp. 123–129, Aug. 2025, doi: 10.18678/dtfd.1585896.
ISNAD
Salkın, Yasemin - Kazak Saltı, Aysun - Erden Ertürk, Sema - Altınkaya, Pınar Müge. “Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy”. Duzce Medical Journal 27/2 (August 1, 2025): 123-129. https://doi.org/10.18678/dtfd.1585896.
JAMA
1.Salkın Y, Kazak Saltı A, Erden Ertürk S, Altınkaya PM. Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy. Duzce Med J. 2025;27:123–129.
MLA
Salkın, Yasemin, et al. “Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy”. Duzce Medical Journal, vol. 27, no. 2, Aug. 2025, pp. 123-9, doi:10.18678/dtfd.1585896.
Vancouver
1.Yasemin Salkın, Aysun Kazak Saltı, Sema Erden Ertürk, Pınar Müge Altınkaya. Investigation of Balance, Kinesiophobia, and Mobility in Older Adults Exposed to Polypharmacy. Duzce Med J. 2025 Aug. 1;27(2):123-9. doi:10.18678/dtfd.1585896
