Ketiapine Bağlı İnterstisyel Akciğer Hastalığı: Olgu Sunumu ve Literatür İncelemesi

Öz

Ketiapin yaygın kullanılan, baş dönmesi, sedasyon ve metabolik yan etkiler gibi birçok yaygın yan etkisi olan bir antipsikotik ilaçtır. Bunlara ek olarak, ilacın bazı nadir yan etkileri de mevcuttur. Bunlar arasında ilaca bağlı interstisyel akciğer hastalığı (drug-induced interstitial lung disease, DI-ILD) çok az bilinmektedir. Bu olgu sunumunda ketiapin kullanımının akciğer yan etkilerini tartışmayı amaçladık. Elli dört yaşında erkek bir şizofreni hastasında ketiapin kullanımını takiben ortaya çıkan, nadir görülen bir yan etki olan interstisyel akciğer hastalığı olgusu sunulmaktadır. Olgumuzda, ketiapin tedavisinin başlamasından sonra ortaya çıkan ve ketiapin kesildikten sonra gerileyen akciğer bulguları nedeniyle DI-ILD düşünülmüştür. Klinisyenler, ketiapin kullanımının bir sonucu olarak ortaya çıkabilecek DI-ILD gibi nadir akciğer yan etkileri konusunda dikkatli olmalıdır.

Anahtar Kelimeler

• Interstisyel akciğer hastalığı
• ketiapin
• şizofreni

Interstitial Lung Disease due to Quetiapine: Case Report and Literature Review

Abstract

Quetiapine is a commonly used antipsychotic drug which has many common side effects such as dizziness, sedation, and metabolic side effects. In addition to them, the drug has also some rare side effects. Among them, little is known about drug-induced interstitial lung disease (DI-ILD). In this case report, we aimed to discuss the side effects of quetiapine use on the lung. We present a case of interstitial lung disease, which is rare side effect, that occurred following quetiapine use in a 54-year-old male schizophrenia patient. In our case, DI-ILD was examined due to the lung findings that occurred after quetiapine treatment started and regressed after quetiapine cessation. Clinicians should be careful about rare lung side effects such as DI-ILD that may develop as a result of quetiapine use.

Keywords

• interstitial lung disease
• quetiapine
• schizophrenia

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