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Management of spontaneous intraparenchymatous hemorrhage: Retrospective analysis of 19 cases treated conservatively or surgery

Yıl 2005, Cilt: 7 Sayı: 1, 19 - 23, 01.03.2005

Öz

Objective: The aim of this study was to assess the treatment modalities of spontaneous intraparenchymatous hematomas. Material and Method: The retrospective analysis of nineteen patients, who attended the neurology or neurosurgery department with spontaneous intraparenchymatous hematoma, was carried out. Results: Of the 9 patients in neurology department, 6 were male and 3 were female. Mean age was 64.5 . The Glasgow Coma Score (GCS) at presentation was 14-15 in four patients and ≤ 7 in 5 patients. Mean hematoma volume was 16.1cc ( 2.5-45.5cc). While 4 patients with GCS 14-15, were discharged with Glasgow Outcome Scale (GOS) 4 or 5, GOS was 1 in all of the patients with GCS ≤ 7. Of the ten patients in neurosurgery department, 6 were male and 4 were female. Mean age was 60.3 . Initial GCS was 9-12 in 4 patients and 3-7 in 6 patients. The hematoma volume varied from 56 cc to 248 cc (mean 96.5 cc). The GOS values at the time of hospital discharge were 5 in 3 patients and 4 in 1 patient in the subgroup of patients with GCS 9-12; while GOS values were 3 or 2 in 3 patients and 1 in 2 patients in group with initial GCS ≤ 7. However, the remaining 1 patient died because of pulmonary embolus at postoperative 7th month. Conclusion: The aim of the conservative treatment in intraparenchymatous hematoma should be the control of blood pressure, maintenance of normal intracranial pressure and cerebral perfusion, and prophylaxis of convulsions. The purpose of surgery is to lessen the mass effect of hematoma and minimize the potential brain damage. The patients can be treated better if collaborative evaluation of neurosurgery and neurology departments can be carried out

Kaynakça

  • Anderson CS, Chakera TMH, Stewart-Wynne EG, Jamrozik KD: Spectrum of primary intracerebral haemorrhage in Perth, Western Australia, 1989–90: incidence and outcome. J Neurol Neurosurg Psychiatry 57: 936–940, 1994.
  • Broderick JP, Brott T, Tomsick T, Huster G, Miller R: The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med 326:733– 736, 1992.
  • Broderick JP, Brott T, Tomsick T, Miller R, Huster G: Intracerebral hemorrhage more than twice as common as subarachnoid hemorrhage. J Neurosurg 78: 188–191, 1993.
  • Giroud M, Gras P, Chadan N, Beuriat P, Milan C, Arveux P, Dumas R: Cerebral haemorrhage in a French prospective population study. J Neurol Neurosurg Psychiatry 54: 595–598, 1991.
  • Qureshi AI, Giles WH, Croft JB: Racial differences in the incidence of intracerebral hemorrhage: effects of blood pressure and education. Neurology 52: 1617–1621, 1999.
  • Skidmore CT, Andrefsky J: Spontaneous intracerebral hemorrhage: epidemiology, pathophysiology, and medical management. Neurosurg Clin N Am 13: 281–288, 2002.
  • Klatsky AL, Armstrong MA, Friedman GD: Alcohol use and subsequent cerebrovascular disease hospitalizations. Stroke20: 741–746, 1989.
  • Iso H, Jacobs DR Jr, Wentworth D, Neaton JD, Cohen JD: Serum cholesterol levels and six- year mortality from stroke in 350,977 men screened for the multiple risk factor intervention trial. N Engl J Med 320: 904–910, 1989.
  • Tanaka H, Ueda Y, Hayashi M: Risk factors for cerebral hemorrhage and cerebral infarction in a Japanese rural community. Stroke 13: 62– 73, 1982.
  • Little KM, Alexander MJ: Medical versus surgical therapy for spontaneous intracranial hemorrhage Neurosurg Clin N Am 13: 339– 347, 2002.
  • Juvela S, Heiskanen O, Poranen A, Valtonen S, Kuurne T, Kaste M, Troupp H: The treatment of spontaneous intracerebral hemorrhage: a prospective randomized trial of surgical and conservative treatment. J Neurosurg 70: 755– 758, 1989.
  • Auer LM, Deinsberger W, Niederkorn K, Gell G, Kleinert R, Schneider G: Endoscopic surgery versus medical treatment for spontaneous intracerebral hematoma: a randomized study. J Neurosurg 70: 530–535, 1989.
  • Batjer HH, Reisch JS, Allen BC, Plaizier LJ, Jen Su C: Failure of surgery to improve outcome in hypertensive putaminal hemorrhage: a prospective randomized trial. Arch Neurol 47: 1103–1106, 1990.
  • Morgenstern LB, Frankowski RF, Shedden P, Pasteur W, Grotta JC: Surgical treatment for intracerebral hemorrhage (STICH): A single- center, randomized clinical trial. Neurology 51: 1359–1363, 1998.
  • Zuccarello M, Brott T, Derex L, Kothari R, Sauerbeck L, Tew J: Early surgical treatment for supratentorial intracerebral hemorrhage: a randomized feasibility study. Stroke 30: 1833– 1839, 1999.
  • Helweg-Larsen S, Sommer W, Strange P, Lester J, Boysen G: Prognosis for patients treated conservatively for spontaneous intracerebral hematomas. Stroke 15: 1045–1048, 1984.
  • Ojemann RG, Heros RC: Spontaneous brain hemorrhage. Stroke 14: 468–475, 1983.
  • Unwin DH, Batjer JJ, Greenlee RG Jr: Management controversy: medical versus surgical therapy for spontaneous intracerebral hemorrhage. Neurosurg Clin North Am 3: 533–537, 1992.
  • Waga S, Yamamoto Y: Hypertensive putaminal hemorrhage: treatment and results. Is surgical treatment superior to conservative one. Stroke 14: 480–485, 1983.
  • Bolander HG, Kourtopoulos H, Liliequist B, Wittboldt S: Treatment of spontaneous intracerebral haemorrhage. A retrospective analysis of 74 consecutive cases with special reference to computer tomographic data. Acta Neurochir (Wien) 67:19–28, 1983.
  • Brambilla GL, Rodriguezy Baena R, Sangiovanni G, Rainoldi F, Locatelli D: Spontaneous intracerebral hemorrhage: medical or surgical treatment. J Neurosurg Sci 27: 95–101, 1983.
  • Morgenstern LB, Demchuk AM, Kim DH, Frankowski RF, Grotta JC: Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage. Neurology 56: 1294– 1299, 2001.
  • Kaya RA, Turkmenoglu O, Ziyal IM, Dalkilic T, Sahin Y, Aydin Y: The effects on prognosis of surgical treatment of hypertensive putaminal hematomas through transsylvian transinsular approach. Surg Neurol. 59:176-183, 2003.

Spontan İntraparenkimal Kanama Tedavisi: Konservatif veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi

Yıl 2005, Cilt: 7 Sayı: 1, 19 - 23, 01.03.2005

Öz

Amaç: Spontan intraparenkimal hematomlarda tedavi yaklaşımlarının değerlendirilmesi. Materyal ve Metot: Nöroloji ve Nöroşirurji kliniklerine bir yıl boyunca başvuran on dokuz ( Nöroloji 9, Nöroşirürji 10 ) spontan intraparenkimal hematomlu ( SİPH ) hastanın konservatif veya cerrahi tedavilerinin retrospektif analizi yapıldı. Bulgular: Nöroloji kliniğine başvuran 9 olgunun 6’sı erkek, 3’ü ise kadındı. Ortalama yaş 64.5 (48-76 yaş). idi. Başvuru sırasında 4 olgunun Glasgow Koma Skoru (GKS) 14-15, 5 olgunun ise 7 ve altı idi. Hematom hacmi ortalama 16.1 cc (2.5-45.5 cc) idi. Başvuru GKS’u 14-15 olan 4 olgu Glasgow çıkış skoru (GOS) 4 veya 5 ile taburcu olurken; GKS’u 7 ve altında olan 5 olgunun hepsinin GOS’u 1 idi. Nöroşirürji kliniğine başvuran 10 olgunun 6’sı erkek, 4’ü ise kadındı. Ortalama yaş 60.3 (47-73 yaş) idi. Başvuru sırasında 4 olgunun GKS’u 9-12, 6 olgunun ise GKS’u 3-7 arasındaydı. Hematom hacmi ortalama 96.5 cc (56-248 cc) idi. Giriş GKS’u 9-12 arasında olan 4 olgudan 3’ü GOS 5 ve 1 olgu GOS 4 olarak taburcu edildi. GKS’u 3-7 arasında olan 6 olgudan üçünün GOS’u 3 veya 2, ikisinin GOS’u 1 idi. Diğer hasta postop. 7. ayda pulmoner emboli gelişmesi nedeniyle öldü. Sonuç: İntraparankimal hematomların konservatif tedavilerinin planlanmasında ve düzenlenmesinde amaç; kan basıncının kontrolü, intrakranial basınç ve serebral perfüzyon basıncının düzenlenmesi normovolemik tutulması ve epileptik (konvulsif) nöbet proflaksisi olmalıdır. Cerrahide ise amaç; hematomun kitle etkisini azaltmak ve potansiyel olarak sekonder beyin hasarının en aza indirilmesi olmalıdır. Hastanın nöroşirürji ve nöroloji kliniklerince beraberce değerlendirilmesinin ve oluşturulacak ortak tedavi protokollerinin hastalara daha yararlı olacağı düşünülmektedir

Kaynakça

  • Anderson CS, Chakera TMH, Stewart-Wynne EG, Jamrozik KD: Spectrum of primary intracerebral haemorrhage in Perth, Western Australia, 1989–90: incidence and outcome. J Neurol Neurosurg Psychiatry 57: 936–940, 1994.
  • Broderick JP, Brott T, Tomsick T, Huster G, Miller R: The risk of subarachnoid and intracerebral hemorrhages in blacks as compared with whites. N Engl J Med 326:733– 736, 1992.
  • Broderick JP, Brott T, Tomsick T, Miller R, Huster G: Intracerebral hemorrhage more than twice as common as subarachnoid hemorrhage. J Neurosurg 78: 188–191, 1993.
  • Giroud M, Gras P, Chadan N, Beuriat P, Milan C, Arveux P, Dumas R: Cerebral haemorrhage in a French prospective population study. J Neurol Neurosurg Psychiatry 54: 595–598, 1991.
  • Qureshi AI, Giles WH, Croft JB: Racial differences in the incidence of intracerebral hemorrhage: effects of blood pressure and education. Neurology 52: 1617–1621, 1999.
  • Skidmore CT, Andrefsky J: Spontaneous intracerebral hemorrhage: epidemiology, pathophysiology, and medical management. Neurosurg Clin N Am 13: 281–288, 2002.
  • Klatsky AL, Armstrong MA, Friedman GD: Alcohol use and subsequent cerebrovascular disease hospitalizations. Stroke20: 741–746, 1989.
  • Iso H, Jacobs DR Jr, Wentworth D, Neaton JD, Cohen JD: Serum cholesterol levels and six- year mortality from stroke in 350,977 men screened for the multiple risk factor intervention trial. N Engl J Med 320: 904–910, 1989.
  • Tanaka H, Ueda Y, Hayashi M: Risk factors for cerebral hemorrhage and cerebral infarction in a Japanese rural community. Stroke 13: 62– 73, 1982.
  • Little KM, Alexander MJ: Medical versus surgical therapy for spontaneous intracranial hemorrhage Neurosurg Clin N Am 13: 339– 347, 2002.
  • Juvela S, Heiskanen O, Poranen A, Valtonen S, Kuurne T, Kaste M, Troupp H: The treatment of spontaneous intracerebral hemorrhage: a prospective randomized trial of surgical and conservative treatment. J Neurosurg 70: 755– 758, 1989.
  • Auer LM, Deinsberger W, Niederkorn K, Gell G, Kleinert R, Schneider G: Endoscopic surgery versus medical treatment for spontaneous intracerebral hematoma: a randomized study. J Neurosurg 70: 530–535, 1989.
  • Batjer HH, Reisch JS, Allen BC, Plaizier LJ, Jen Su C: Failure of surgery to improve outcome in hypertensive putaminal hemorrhage: a prospective randomized trial. Arch Neurol 47: 1103–1106, 1990.
  • Morgenstern LB, Frankowski RF, Shedden P, Pasteur W, Grotta JC: Surgical treatment for intracerebral hemorrhage (STICH): A single- center, randomized clinical trial. Neurology 51: 1359–1363, 1998.
  • Zuccarello M, Brott T, Derex L, Kothari R, Sauerbeck L, Tew J: Early surgical treatment for supratentorial intracerebral hemorrhage: a randomized feasibility study. Stroke 30: 1833– 1839, 1999.
  • Helweg-Larsen S, Sommer W, Strange P, Lester J, Boysen G: Prognosis for patients treated conservatively for spontaneous intracerebral hematomas. Stroke 15: 1045–1048, 1984.
  • Ojemann RG, Heros RC: Spontaneous brain hemorrhage. Stroke 14: 468–475, 1983.
  • Unwin DH, Batjer JJ, Greenlee RG Jr: Management controversy: medical versus surgical therapy for spontaneous intracerebral hemorrhage. Neurosurg Clin North Am 3: 533–537, 1992.
  • Waga S, Yamamoto Y: Hypertensive putaminal hemorrhage: treatment and results. Is surgical treatment superior to conservative one. Stroke 14: 480–485, 1983.
  • Bolander HG, Kourtopoulos H, Liliequist B, Wittboldt S: Treatment of spontaneous intracerebral haemorrhage. A retrospective analysis of 74 consecutive cases with special reference to computer tomographic data. Acta Neurochir (Wien) 67:19–28, 1983.
  • Brambilla GL, Rodriguezy Baena R, Sangiovanni G, Rainoldi F, Locatelli D: Spontaneous intracerebral hemorrhage: medical or surgical treatment. J Neurosurg Sci 27: 95–101, 1983.
  • Morgenstern LB, Demchuk AM, Kim DH, Frankowski RF, Grotta JC: Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage. Neurology 56: 1294– 1299, 2001.
  • Kaya RA, Turkmenoglu O, Ziyal IM, Dalkilic T, Sahin Y, Aydin Y: The effects on prognosis of surgical treatment of hypertensive putaminal hematomas through transsylvian transinsular approach. Surg Neurol. 59:176-183, 2003.
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Research Article
Yazarlar

Merih İş Bu kişi benim

Aytaç Can Bu kişi benim

Ayhan Öztürk Bu kişi benim

Selçuk Atakay Bu kişi benim

Ferruh Gezen Bu kişi benim

Yayımlanma Tarihi 1 Mart 2005
Yayımlandığı Sayı Yıl 2005 Cilt: 7 Sayı: 1

Kaynak Göster

APA İş, M., Can, A., Öztürk, A., Atakay, S., vd. (2005). Spontan İntraparenkimal Kanama Tedavisi: Konservatif veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi. Duzce Medical Journal, 7(1), 19-23.
AMA İş M, Can A, Öztürk A, Atakay S, Gezen F. Spontan İntraparenkimal Kanama Tedavisi: Konservatif veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi. Duzce Med J. Mart 2005;7(1):19-23.
Chicago İş, Merih, Aytaç Can, Ayhan Öztürk, Selçuk Atakay, ve Ferruh Gezen. “Spontan İntraparenkimal Kanama Tedavisi: Konservatif Veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi”. Duzce Medical Journal 7, sy. 1 (Mart 2005): 19-23.
EndNote İş M, Can A, Öztürk A, Atakay S, Gezen F (01 Mart 2005) Spontan İntraparenkimal Kanama Tedavisi: Konservatif veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi. Duzce Medical Journal 7 1 19–23.
IEEE M. İş, A. Can, A. Öztürk, S. Atakay, ve F. Gezen, “Spontan İntraparenkimal Kanama Tedavisi: Konservatif veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi”, Duzce Med J, c. 7, sy. 1, ss. 19–23, 2005.
ISNAD İş, Merih vd. “Spontan İntraparenkimal Kanama Tedavisi: Konservatif Veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi”. Duzce Medical Journal 7/1 (Mart 2005), 19-23.
JAMA İş M, Can A, Öztürk A, Atakay S, Gezen F. Spontan İntraparenkimal Kanama Tedavisi: Konservatif veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi. Duzce Med J. 2005;7:19–23.
MLA İş, Merih vd. “Spontan İntraparenkimal Kanama Tedavisi: Konservatif Veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi”. Duzce Medical Journal, c. 7, sy. 1, 2005, ss. 19-23.
Vancouver İş M, Can A, Öztürk A, Atakay S, Gezen F. Spontan İntraparenkimal Kanama Tedavisi: Konservatif veya Cerrahi Uygulanan 19 Olgunun Retrospektif Analizi. Duzce Med J. 2005;7(1):19-23.
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