Anticholinergic Syndrome in a Pediatric Patient after Resuscitation

Yıl 2005, Cilt: 7 Sayı: 2, 39 - 41, 01.07.2005

Yavuz Demiraran Abdulkadir İskender Buket Kocaman

Öz

Central anticholinergic syndrome is considered to reveal after blocking of central and peripheral cholinergic muscarinic receptors. Although central anticholinergic syndrome can be diagnosed with its clinical signs, the definitive diagnose can be made according to the response with physostigmin administration. It is aimed to discuss the therapy of a child who revealed the clinical signs of central anticholinergic syndrome (agitation, mydriasis, excitation, tachycardia, flushing, and fever) after resuscitation

Anahtar Kelimeler

anticholinergic syndrome, resuscitation, postoperative

Postoperatif Kardiyak Arrest Gelişen Bir Çocukta Resusitasyon Sonrası Ortaya Çıkan Antikolinerjik Sendrom

Öz

Antikolinerjik sendrom, kolinerjik muskarinik reseptörlerin santral ve periferik olarak blokajı ile oluşur. Santral antikolinerjik sendrom bulguları klinik olarak tanınabilmesine rağmen, kesin tanı, klinik bulguların oluşmasından sonra, fizostigmin verildiğinde hastanın bulgularının düzelmesiyle konulabilir. Biz de resusitasyon sonrası bir çocuk hastada, tedavi edilemeyen ajitasyon, midriyazis, uyuklama, eksitasyon, taşikardi, kızarıklık ve ateş gibi klinik bulguların tespit edilmesi ile santral antikolinerjik sendrom düşündüğümüz olguyu sunmayı amaçladık

Anahtar Kelimeler

Antikolinerjik sendrom, resusitasyon, postoperatif

Kaynakça

• Shannon BE. Poisonings and ingestions. In: Manual of Emergency Medicine eds. Jenkins JL, Loscalzo J, Braen RG. Third Edition. Little Brown and Company. USA. 435-492, 1995.
• Rizzi RR, Ho J. Post resuscitation central anticholinergic syndrome. Resuscitation, 61: 101-102, 2004.
• Schultz U, ldelberger R, Rossaint R, Buhre W. Central anticholinergic syndrome in a child undergoing circumcision. Acta Anaesthesiol Scand, 46: 224-226, 2002.
• Martin B, Howell PR. Two cases of central anticholinergic syndrome following anaesthesia and its treatment with physostigmine. Eur J Anaesthesiol, 14: 467- 470, 1997.
• Madi-Jebara S, Yazigi A, Haddad F, Hayek G, Antakly MC. The central anticholinergic syndrome, a rare cause of uncontrollable agi- tation after coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth, 16: 665- 666, 2002.
• Siberry G, lannone R. The Harriet Lane Handbook. 15th ed,, p. 638-639, 2000.
• Gregory G. Pediatric Anesthesia. 3rd ed, p. 901, 1994.
• Rupreht J, Dworacek B. The central anticholinergic syndrome in the postoperative period. In: Nunn JF, Utting JE, Brown BR (eds) General anaesthesia, 5th edn. Butterworths, London, p 1141-1148, 1989 9. Link J
• Papadopoulos G, Dopjans D, Guggenmoos-Holzmann I, Eyrich KEur J. Distinct central anticholinergic syndrome following general anaesthesia. Anaesthesiol,14:15-23, 1997.
• Hall RCW, Fox J, Stickney SK. Anticholinerjic delirium: etiology, presentation, diagnonosis and management . J Pyschoactive Drugs, 10: 237-241, 1978.
• Granacher RP, Baldessarini RJ. Physostigmine its use in acute anticholinergic syndrome with antidepressant and antiparkinson drugs. Arc Gen Psychiatry, 32: 375-380, 1975.