Chronic tophaceus gout nephropathy with hipopotasemia (a case report)

Year 2007, Volume: 9 Issue: 2, 40 - 45, 01.07.2007

Özgür Erdem Vedat Göral İsmail Hamdi Kara

Abstract

Gout disease is a common reason for acute arthritis cases. It can appear in different clinical versions. Recurring acute arthritis attacks, formation of tophaceus around the joint and other connective tissue (especially seen at the first metatarsophalangeal joint and earlobe), uric acid stones and gout nephropathy are the most commonly encountered. Besides it has been seen in elder ages and on men with 95% rates, when it is identified on women, the 90% of them are post-menopausal women. As well as causing the renal disease, it has been told that the gout could contribute the development of the chronic renal failure. However, it has not done a certain distinction regarding the facts that the gout has expanded related to chronic renal failure and the nephropathy growth after the gout in literature works. In this case, the progress of nephropathy with hipopotasemia on a post-menopause woman who has got chronic tophaceus gout and chronic renal failure has been found important to be discussed

Keywords

Chronic tophaceus gout, Chronic renal failure, Hypopotasemia, Nephropathy

Hipopotasemi ile Seyreden Kronik Tofuslu Gut Nefropatisi (Olgu Sunumu)

Abstract

Gut, akut artritin sik görülen bir nedenidir. Farkli klinik sekillerde karsimiza çikabilir. Tekrarlayan akut artrit ataklari, eklem çevresi ile diger bag dokularda tofüs olusumu (özellikle birinci metatarsofalangial eklem ile kulak kepçesinde görülür), ürik asit taslari ve gut nefropatisi bunla rdan en sik görülenleridir. Ileri yaslarda ve %95 erkeklerde görülmekle beraber, kadinlarda ise %90 postmenopozal kadinlarda saptanir. Gut böbrek hastaligina neden olmakla beraber, kronik böbrek yetmezligi (KBY) gelisimine de katkida bulunabilecegi daha az siklikla bildirilmistir. Bununla beraber literatür çalismalarinda gut’un KBY’ye bagli gelistigi veya gut sonrasi nefropati gelistigi ile ilgili kesin bir ayirim yapilmamistir. Burada kronik tofüslü gut ile beraber KBY’i bulunan postmenopozal bir kadinda nefropatinin hipopotasemi ile seyretmesi tartisilmaya deger bulundu

Keywords

Kronik tofüslü gut, Kronik böbrek yetmezligi, Hipopotasemi, Nefropati

References

• Öksüz MC, Samanci N: Kristal artropatilerinden gut. STED. 2, 303, 2003.
• Yoleri Ö, Öngen B, Sengül I, Ölmez N, Memis A, Esmeli F: Gut hastaligi seyrinde görülen polinöropati, bir olgu sunumu. Romatizma. 20, 2005.
• Underwood M: Gut tanisi ve tedavisi. BMJ. 332: 1315-1316, 2006.
• Gündüz OH, Yilmaz L, Bodur H, Akyürek N: Erken baslangiçli kronik tofüslü gut. Romatizma. 16:2, 2001.
• Güzel R, Sarpel T, Kozanoglu E, Paydas S: Ailesel nefropati öyküsü olan premenopozal bir kadinda kronik tofüslü gut olgusu. Ege Fiz. Tip Reh. Der. 7(3-4): 141-145, 2001.
• Süldür N, Beyazova M, Gökçe-Kutsal Y: Kristal artropatileri. Fiziksel Tip ve Rehabilitasyon, Ankara,Günes Kitabevi. pp: 1630-1653, 2000.
• Gibson T, Waterworth R, Hatfield P, Robinson G and Bremner K: Hyperüricameia, gout and kidney function in New Zealand Maori men. British Journal of Rheumatolog 23:276-28, 1984.
• Recht MP, Seragini F, Kramer J, Dalinka MK, Hurtgen K, Resnick D: Isolated or dominant lesion of the patella in gout: A report of seven patients. Skeletal Radiol. 23:113-116, 1994.
• Gümüsdis G, Doganavsargil E: Kristallere bagli artropatiler. Klinik Romatoloji. 1. basim. Gürbüz Gümüsdis (ed): Istanbul. Deniz Matbaacilik. pp: 489-496, 1999.
• Vecchio PC, Emmerson BT: Gout due to renal disease. British Journal of Rheumatology. 31:63-65, 1992.
• Edwards NL. Gout. Clinical and laboratory features. In Klippel JH, Weyand CM, Wortmann RL (eds): Primer on the Rheumatic Diseases. Georgia. Arthritis Foundation. pp: 234-239, 1997.
• Kiykim AA, Çamsari A: Ödemli Hastalarda Diüretik Kullanim. Anadolu Kardiyoloji Dergisi 3: 65-70, 2003.
• Yalçin BM, Sahin EM: Birinci basamakta esansiyel hipertansiyona yaklasim. Trakya Üniversitesi Tip Fakültesi Dergisi. 19 (3- 4): 62-170, 2002.
• Zungur M, Yildiz A: Hipertansif Hastaya Yaklasim. STED 13, 297, 2004.
• Chobanian AV, Bakris GL, Black HR, Cushman WC, Gren LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Rochella EJ: Seventh report of the joint national committee on prevention, detection, evaluation and treatment of high blood pressure. Hypertension. 42:1206- 1252, 2003.