Case Report
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Posterior Fossa Ependimomunun Yaşlı Hastada Nadir Bir Prezentasyonu: Olgu Sunumu

Year 2024, Issue: Early Access
https://doi.org/10.18678/dtfd.1516994

Abstract

Serebellar ependimomlar nadir görülen neoplazmlardır ve yaşlı hastalarda daha da nadirdir. Bu olgu sunumunda, bir yıl süresince ilerleyici genel durum bozukluğu, idrar yapamama, sol tarafta güçsüzlük, hafıza kaybı ve uykusuzluk öyküsü ile başvuran 75 yaşında bir erkek hasta sunulmuştur. Fizik muayenede sol taraflı hemiparezi ve hafif konfüzyon görüldü. Kranial manyetik rezonans görüntüleme (MRG), dördüncü ventrikülden kaynaklanan, 22x15x20 mm boyutlarında heterojen olarak kontrastlanan bir lezyon ve hidrosefali bulguları gösterdi. Hastaya hidrosefaliyi tedavi etmek için tümör rezeksiyonu ve ventriküloperitoneal (VP) şant yerleştirildi. Ameliyat sonrası MRG’de, rezidüel tümör görülmedi ve hasta kademeli olarak klinik iyileşme gösterdi. Hemiparezi kısmi iyileşme gösteren ve genel durumu stabilize olan hasta bunun ardından taburcu edildi. Patolojik inceleme, Dünya Sağlık Örgütü (DSÖ) evre II ependimom tanısını doğruladı. Hasta şu anda üç aylık takiptedir.

References

  • Hsu HI, Hsu SS, Chung WY, Yip CM, Liu SH, Liao WC. Adult posterior fossa anaplastic ependymoma, case series and literature review. World Neurosurg. 2022;158:205-9.
  • Thompson YY, Ramaswamy V, Diamandis P, Daniels C, Taylor MD. Posterior fossa ependymoma: current insights. Childs Nerv Syst. 2015;31(10):1699-706.
  • Kawano N, Yagishita S, Komatsu K, Suwa T, Oka H, Utsuki S, et al. Cerebellar clear cell ependymoma mimicking hemangioblastoma: its clinical and pathological features. Surg Neurol. 1999;51(3):281-7.
  • Hayashi T, Miyazaki H, Ishiyamai N, Kameyama K. Immunohistochemical study is helpful for the diagnosis of cerebellar clear cell ependymoma with atypical radiological findings--case report. No Shinkei Geka. 2005;33(11):1113-7. Japanese.
  • Hayashi T, Inamasu J, Kanai R, Sasaki H, Shinoda J, Hirose Y. Clinical, histological, and genetic features of fourth ventricle ependymoma in the elderly. Case report. Neurol Med Chir (Tokyo). 2012;52(8):611-6.
  • Lampros M, Vlachos N, Alexiou GA. Ependymomas in children and adults. Adv Exp Med Biol. 2023;1405:99-116.
  • Schaff LR, Mellinghoff IK. Glioblastoma and other primary brain malignancies in adults: A review. JAMA. 2023;329(7):574-87.
  • İş M, Gezen F, Yıldız KH, Akyüz F, Can A. Radiation necrosis that is diagnosed by magnetic resonance spektroscopy in an anaplastic ependymoma case: Case report. Duzce Med J. 2005;7(2):23-8.
  • Calıs MD. Intracranial ependymoma with extremely rare extraneural metastasis. J Cancer Res Ther. 2024;20(1):460-3.
  • Bondy ML, Scheurer ME, Malmer B, Barnholtz-Sloan JS, Davis FG, Il’yasova D, et al. Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer. 2008;113(7 Suppl):1953-68.
  • Deng J, Xue C, Liu X, Li S, Zhou J. Differentiating between adult intracranial medulloblastoma and ependymoma using MRI. Clin Radiol. 2023;78(3):e288-93.
  • Yoo KH, Marianayagam NJ, Park DJ, Persad A, Zamarud A, Shaghaghian E, et al. Stereotactic radiosurgery for ependymoma in pediatric and adult patients: A single-institution experience. Neurosurgery. 2024;95(2):456-68.

An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report

Year 2024, Issue: Early Access
https://doi.org/10.18678/dtfd.1516994

Abstract

Cerebellar ependymomas are rare neoplasms, even more so in elderly patients. In this case report, a 75-year-old male patient admitted with a one-year history of progressive general decline, urinary retention, left-sided weakness, memory loss, and insomnia was presented. Physical examination revealed left-sided hemiparesis and mild confusion. Cranial magnetic resonance imaging (MRI) showed a heterogeneously enhancing lesion measuring 22x15x20 mm originating from the fourth ventricle, with signs of hydrocephalus. The patient underwent tumor resection and placement of a ventriculoperitoneal (VP) shunt to address hydrocephalus. Postoperative MRI revealed no residual tumor, and the patient experienced gradual clinical improvement. Hemiparesis showed partial recovery, the overall condition stabilized, and he was subsequently discharged. Pathological examination confirmed a diagnosis of World Health Organization (WHO) grade II ependymoma. The patient is currently on a three-month follow-up.

References

  • Hsu HI, Hsu SS, Chung WY, Yip CM, Liu SH, Liao WC. Adult posterior fossa anaplastic ependymoma, case series and literature review. World Neurosurg. 2022;158:205-9.
  • Thompson YY, Ramaswamy V, Diamandis P, Daniels C, Taylor MD. Posterior fossa ependymoma: current insights. Childs Nerv Syst. 2015;31(10):1699-706.
  • Kawano N, Yagishita S, Komatsu K, Suwa T, Oka H, Utsuki S, et al. Cerebellar clear cell ependymoma mimicking hemangioblastoma: its clinical and pathological features. Surg Neurol. 1999;51(3):281-7.
  • Hayashi T, Miyazaki H, Ishiyamai N, Kameyama K. Immunohistochemical study is helpful for the diagnosis of cerebellar clear cell ependymoma with atypical radiological findings--case report. No Shinkei Geka. 2005;33(11):1113-7. Japanese.
  • Hayashi T, Inamasu J, Kanai R, Sasaki H, Shinoda J, Hirose Y. Clinical, histological, and genetic features of fourth ventricle ependymoma in the elderly. Case report. Neurol Med Chir (Tokyo). 2012;52(8):611-6.
  • Lampros M, Vlachos N, Alexiou GA. Ependymomas in children and adults. Adv Exp Med Biol. 2023;1405:99-116.
  • Schaff LR, Mellinghoff IK. Glioblastoma and other primary brain malignancies in adults: A review. JAMA. 2023;329(7):574-87.
  • İş M, Gezen F, Yıldız KH, Akyüz F, Can A. Radiation necrosis that is diagnosed by magnetic resonance spektroscopy in an anaplastic ependymoma case: Case report. Duzce Med J. 2005;7(2):23-8.
  • Calıs MD. Intracranial ependymoma with extremely rare extraneural metastasis. J Cancer Res Ther. 2024;20(1):460-3.
  • Bondy ML, Scheurer ME, Malmer B, Barnholtz-Sloan JS, Davis FG, Il’yasova D, et al. Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer. 2008;113(7 Suppl):1953-68.
  • Deng J, Xue C, Liu X, Li S, Zhou J. Differentiating between adult intracranial medulloblastoma and ependymoma using MRI. Clin Radiol. 2023;78(3):e288-93.
  • Yoo KH, Marianayagam NJ, Park DJ, Persad A, Zamarud A, Shaghaghian E, et al. Stereotactic radiosurgery for ependymoma in pediatric and adult patients: A single-institution experience. Neurosurgery. 2024;95(2):456-68.
There are 12 citations in total.

Details

Primary Language English
Subjects Brain and Nerve Surgery (Neurosurgery)
Journal Section Case Report
Authors

Bilal Bahadır Akbulut 0000-0002-7983-5056

Hüseyin Biçeroğlu 0000-0003-2306-0826

Mustafa Serdar Bölük 0000-0002-9406-4114

Taşkın Yurtseven 0000-0001-7982-8115

Early Pub Date November 25, 2024
Publication Date
Submission Date July 16, 2024
Acceptance Date November 4, 2024
Published in Issue Year 2024 Issue: Early Access

Cite

APA Akbulut, B. B., Biçeroğlu, H., Bölük, M. S., Yurtseven, T. (2024). An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report. Duzce Medical Journal(Early Access). https://doi.org/10.18678/dtfd.1516994
AMA Akbulut BB, Biçeroğlu H, Bölük MS, Yurtseven T. An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report. Duzce Med J. November 2024;(Early Access). doi:10.18678/dtfd.1516994
Chicago Akbulut, Bilal Bahadır, Hüseyin Biçeroğlu, Mustafa Serdar Bölük, and Taşkın Yurtseven. “An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report”. Duzce Medical Journal, no. Early Access (November 2024). https://doi.org/10.18678/dtfd.1516994.
EndNote Akbulut BB, Biçeroğlu H, Bölük MS, Yurtseven T (November 1, 2024) An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report. Duzce Medical Journal Early Access
IEEE B. B. Akbulut, H. Biçeroğlu, M. S. Bölük, and T. Yurtseven, “An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report”, Duzce Med J, no. Early Access, November 2024, doi: 10.18678/dtfd.1516994.
ISNAD Akbulut, Bilal Bahadır et al. “An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report”. Duzce Medical Journal Early Access (November 2024). https://doi.org/10.18678/dtfd.1516994.
JAMA Akbulut BB, Biçeroğlu H, Bölük MS, Yurtseven T. An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report. Duzce Med J. 2024. doi:10.18678/dtfd.1516994.
MLA Akbulut, Bilal Bahadır et al. “An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report”. Duzce Medical Journal, no. Early Access, 2024, doi:10.18678/dtfd.1516994.
Vancouver Akbulut BB, Biçeroğlu H, Bölük MS, Yurtseven T. An Uncommon Occurrence of Posterior Fossa Ependymoma in Elderly Patient: A Case Report. Duzce Med J. 2024(Early Access).