EN
Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies
Abstract
Purpose: This study aimed to evaluate the accuracy and comprehensiveness of the responses generated by GPT-4o and Claude-3.5 Sonnet to the most frequently asked questions about endodontic emergencies.
Materials and Methods: The most frequently asked questions about nine different topics (inferior alveolar nerve block, sodium hypochlorite accidents, aspiration of dental materials, separated instruments, perforation, transportation, Ca(OH)2 extrusion, root filling, and flare-up) in endodontics were generated by GPT 3.5. Each question was asked to the both GPT-4o and Claude 3.5 Sonnet. Two authors independently scored the responses. Accuracy and comprehensiveness were assessed for each question using Likert scales. The data were statistically analyzed using the Mann‒Whitney U test, the Kruskal‒Wallis test. Significance level was set at 0.05.
Results: Responses generated by both GPT-4o and Claude 3.5 Sonnet to a total of 81 open-ended questions were evaluated. The two models yielded similar results in terms of accuracy and comprehensiveness (p > 0.05). The topics of root filling, perforation, and flare-up have the lowest accuracy scores; and root filling and separated instruments have the lowest comprehensiveness scores for GPT-4o (p < 0.05). The accuracy of Claude 3.5's responses did not show significant differences between the topics (p > 0.05); however, separated instruments had the lowest comprehensiveness scores (p < 0.05).
Conclusion: The accuracy and comprehensiveness scores of GPT-4 and Claude 3.5 Sonnet are statistically similar. Despite the high levels of accuracy and comprehensiveness shown by GPT-4o and Claude 3.5 Sonnet, they do not yet have the effect of replacing the operator in endodontic procedures.
Keywords
Supporting Institution
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Ethical Statement
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Thanks
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References
- Li ZQ, Wang XF, Liu JP. Publication Trends and Hot Spots of ChatGPT’s Application in the Medicine. J Med Syst. 2024;48(1):52. doi:10.1007/s10916-024-02074-y.
- 2. Jeon SJ, Yun JP, Yeom HG, Shin WS, Lee JH, Jeong SH, et al. Deep-learning for predicting C-shaped canals in mandibular second molars on panoramic radiographs. Dentomaxillofac Radiol. 2021;50(5):20200513. doi:10.1259/dmfr.20200513.
- 3. Brignardello-Petersen R. Artificial intelligence system seems to be able to detect a high proportion of periapical lesions in cone-beam computed tomographic images. J Am Dent Assoc. 2020;151(9):e83. doi:10.1016/j.adaj.2020.04.006.
- 4. Saghiri MA, Garcia-Godoy F, Gutmann JL, Lotfi M, Asgar K. The reliability of artificial neural network in locating minor apical foramen: a cadaver study. J Endod. 2012;38(8):1130–4. doi:10.1016/j.joen.2012.05.004.
- 5. Fukuda M, Inamoto K, Shibata N, Ariji Y, Yanashita Y, Kutsuna S, et al. Evaluation of an artificial intelligence system for detecting vertical root fracture on panoramic radiography. Oral Radiol. 2020;36(4):337–343. doi:10.1007/s11282-019-00409-x.
- 6. Ghanem YK, Rouhi AD, Al-Houssan A, Saleh Z, Moccia MC, Joshi H, et al. Dr. Google to Dr. ChatGPT: assessing the content and quality of artificial intelligence-generated medical infor- mation on appendicitis. Surg Endosc. 2024;38(5):2887–2893. doi:10.1007/s00464-024-10739-5.
- 7. Kanthavel R, Anathajothi K, Balamurugan S, Ganesh RK. Arti- ficial Intelligent Techniques for Wireless Communication and Networking. John Wiley & Sons; 2022.
- 8. OpenAI. Hello GPT-4o [Web Page]; 2024. Available from: https: //openai.com/index/hello-gpt-4o/.
Details
Primary Language
English
Subjects
Endodontics
Journal Section
Research Article
Early Pub Date
April 30, 2025
Publication Date
April 30, 2025
Submission Date
November 4, 2024
Acceptance Date
March 18, 2025
Published in Issue
Year 2025 Volume: 52 Number: 1
APA
Sarı, M., & Tufenkci, P. (2025). Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies. European Annals of Dental Sciences, 52(1), 10-16. https://doi.org/10.52037/eads.2025.0002
AMA
1.Sarı M, Tufenkci P. Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies. EADS. 2025;52(1):10-16. doi:10.52037/eads.2025.0002
Chicago
Sarı, Merve, and Pelin Tufenkci. 2025. “Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies”. European Annals of Dental Sciences 52 (1): 10-16. https://doi.org/10.52037/eads.2025.0002.
EndNote
Sarı M, Tufenkci P (April 1, 2025) Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies. European Annals of Dental Sciences 52 1 10–16.
IEEE
[1]M. Sarı and P. Tufenkci, “Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies”, EADS, vol. 52, no. 1, pp. 10–16, Apr. 2025, doi: 10.52037/eads.2025.0002.
ISNAD
Sarı, Merve - Tufenkci, Pelin. “Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies”. European Annals of Dental Sciences 52/1 (April 1, 2025): 10-16. https://doi.org/10.52037/eads.2025.0002.
JAMA
1.Sarı M, Tufenkci P. Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies. EADS. 2025;52:10–16.
MLA
Sarı, Merve, and Pelin Tufenkci. “Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies”. European Annals of Dental Sciences, vol. 52, no. 1, Apr. 2025, pp. 10-16, doi:10.52037/eads.2025.0002.
Vancouver
1.Merve Sarı, Pelin Tufenkci. Evaluation of the Competency of Large Language Models GPT-4o and Claude 3.5 Sonnet in Endodontic Emergencies. EADS. 2025 Apr. 1;52(1):10-6. doi:10.52037/eads.2025.0002