Review

The Bıologıcal Importance of Curcumın

Volume: 6 Number: 1 June 24, 2020
EN

The Bıologıcal Importance of Curcumın

Abstract

Turmeric (Curcuma longa); In India, China and South East Asia, spices are widely used as aromatic stimulants, food preservatives and coloring materials. Among the people as "castor saffron, turmeric, turmeric, saffron root"; Turmeric as the commonly used name is a yellow-orange colored polyphenolic natural substance derived from C. longa rhizomes. In traditional medicine for inflammation and tumors, biliary disorders, anorexia, cough, topical wounds, diabetic wounds, hepatic disorders, rheumatism and sinusitis. It was used as a medicine. In recent years, extensive studies have been conducted to determine the biological activities and pharmacological effects of turmeric and its extracts. Curcumin, which is the main yellow bioactive component of turmeric, is known to have a wide bioactivity such as anti-inflammatory, antioxidant, anticarcinogenic, antidiabetic, antibacterial, antifungal, antiprotozoal, antiviral, antifibrotic, immunomodulator and antiulcer. Safety assessment studies show that curcumin is well tolerated without toxic effects when used in very high doses. Therefore, curcumin is a substance of high biological importance with the development potential of modern medicine for the treatment of various diseases. For this reason, more scientific studies on curcumin should be done and all the dark sides about this important compound should be illuminated.

Keywords

References

  1. AKBİK, D. GHADİRİ, M.CHRZANOWSKİ, W. ROHANİZADEH, R. (2014). Curcumin as a Wound Healing Agent. Life Sciences, 116(1), 1-7.
  2. AKRAM, M. SHAHAB-UDDİN, A. A. USMANGHANİ, K. HANNAN, A. MOHİUDDİN, E. ASİF, M. (2010). Curcuma longa and curcumin: a review article. Rom J Biol Plant Biol, 55, 65–70.
  3. ANAND, P. THOMAS, S. KUNNUMAKKARA, A., SUNDARAM, C., HARİKUMAR, K. B., SUNG, B., THARAKAN, S. T. MİSRA, K. PRİYADARSİNİ, I. K., RAJASEKHARAN, K. N. AGGARWAL , B. B. (2008). Biological activities of curcumin and its analogues(congeners) made by man and mother nature. Biochem Pharm, 7(6), 1590–611.
  4. ARTİCO , M. Dİ SANTO, R., COSTİ , R., NOVELLİNO , E., GRECO, G., MASSA, S., TRAMONTONO, E., MARONGİU, M.E., DE MONTİS, A., LA COLLA, P. (1998). Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-I intergrase. Journal of Medicinal Chemistry, 41, 3948-3960.
  5. BOURNE, K. Z. BOURNE, N. REİSİNG, S. F. STANBERRY, L. R. (1999). Plant products as topical microbicide candidates: assessment of in vitro and in vivo activity against herpes simplex virus type 2. Antivir. Res., 42, 219-226.
  6. BOZ, İ. (2013). Kurkumin Takviyesinin Sıçanlarda Ekzantrik Egzersizle Oluşan Kas Hasarı Üzerine Etkisi. Yüksek Lisans Tezi, T.C. Selçuk Üniversitesi Sağlık Bilimleri Enstitüsü, Konya.
  7. BRİGHT, J. J. (2007). Curcumin and autoimmune disease. Adv Exp Med Biol, 595, 425–451.
  8. BURKE JR. T. R., FESEN, M. R. MAZUMDER, A. WANG, J. CAROTHERS, A. M. GRUNBERGER, D. DRİSCOLL, J. KOHN, K., POMMİER, Y. (1995). Hydroxylated aromatic inhibitors of HIV-1 integrase. J. Med. Chem., 38 , 4171-4178.

Details

Primary Language

English

Subjects

-

Journal Section

Review

Authors

Merve Arlı This is me
Türkiye

Publication Date

June 24, 2020

Submission Date

May 24, 2020

Acceptance Date

June 19, 2020

Published in Issue

Year 2020 Volume: 6 Number: 1

APA
Arlı, M., & Çelik, H. (2020). The Bıologıcal Importance of Curcumın. Eastern Anatolian Journal of Science, 6(1), 21-34. https://izlik.org/JA28MF96HA
AMA
1.Arlı M, Çelik H. The Bıologıcal Importance of Curcumın. Eastern Anatolian Journal of Science. 2020;6(1):21-34. https://izlik.org/JA28MF96HA
Chicago
Arlı, Merve, and Hülya Çelik. 2020. “The Bıologıcal Importance of Curcumın”. Eastern Anatolian Journal of Science 6 (1): 21-34. https://izlik.org/JA28MF96HA.
EndNote
Arlı M, Çelik H (June 1, 2020) The Bıologıcal Importance of Curcumın. Eastern Anatolian Journal of Science 6 1 21–34.
IEEE
[1]M. Arlı and H. Çelik, “The Bıologıcal Importance of Curcumın”, Eastern Anatolian Journal of Science, vol. 6, no. 1, pp. 21–34, June 2020, [Online]. Available: https://izlik.org/JA28MF96HA
ISNAD
Arlı, Merve - Çelik, Hülya. “The Bıologıcal Importance of Curcumın”. Eastern Anatolian Journal of Science 6/1 (June 1, 2020): 21-34. https://izlik.org/JA28MF96HA.
JAMA
1.Arlı M, Çelik H. The Bıologıcal Importance of Curcumın. Eastern Anatolian Journal of Science. 2020;6:21–34.
MLA
Arlı, Merve, and Hülya Çelik. “The Bıologıcal Importance of Curcumın”. Eastern Anatolian Journal of Science, vol. 6, no. 1, June 2020, pp. 21-34, https://izlik.org/JA28MF96HA.
Vancouver
1.Merve Arlı, Hülya Çelik. The Bıologıcal Importance of Curcumın. Eastern Anatolian Journal of Science [Internet]. 2020 Jun. 1;6(1):21-34. Available from: https://izlik.org/JA28MF96HA