Characterization and antifungal applications of azole functional mesoporous and hollow silica nanocomposites

Yıl 2022, , 151 - 156, 30.12.2022

Sedef Kaptan Usul , Ayşe Aslan , Didem Özçimen

https://doi.org/10.46239/ejbcs.1033670

Öz

In this study, mesoporous (MSN) and hollow (HSS) silica nanoparticles were interacted with vinyltriazole to increase the number of amine groups on the surface. The characterization and antibacterial properties of the prepared nanocomposite structures were investigated. In the characterization of nanocomposites, FTIR and XRD analysis was used to determine the interaction of MSN and HSS with vinyltriazole, the presence of azole groups on the surface, and TGA analysis to examine their thermal properties. SEM analysis was performed to determine the morphology of nanocomposites. The antifungal properties of nanocomposite structures have been proven by the MIC method.

Anahtar Kelimeler

mesoporous silica, hollow silica, vinyltriazole

Azol fonksiyonel gözenekli ve içi boş silika nanokompozitlerin karakterizasyonu ve antifungal uygulamaları

Öz

Bu çalışmada çok gözenekli (MSN) ve tek gözenekli (HSS) silika nanopartiküllerin yüzeyinde, viniltriazol (VTri) monomerinin polimerizasyon reaksiyonu ile amin grupları oluşturulmuştur. Hazırlanan nanokompozit yapıların karakterizasyonu ve antifungal özelliği incelenmiştir. Nanokompozitlerin karakterizasyonunda MSN ve HSS' nın viniltriazol ile etkileşimini, yüzeydeki azol gruplarının varlığını belirlemek için FTIR ve XRD analizi, termal özelliklerini incelemek için TGA analizi yapılmıştır. Nanokompozitlerin morfolojisini belirlemek için SEM analizi yapılmıştır. Nanokompozit yapıların antifungal özellikleri MİK yöntemi ile kanıtlanmıştır.

Anahtar Kelimeler

gözenekli silika, tek gözenekli silika, viniltriazol

Kaynakça

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