Thiazole: A promising scaffold in medicinal chemistry

Abdüllatif Karakaya; Emine Rana Bağci; Betül Kaya; Ulviye Acar Çevik; Zafer Asım Kaplancıklı

doi:10.55971/EJLS.1929137

Thiazole: A promising scaffold in medicinal chemistry

Abstract

Thiazole, a five-membered heterocyclic skeleton found in numerous commercially marketed drugs and various natural products, has gained significant attention in the field of medicinal chemistry. Thiazole derivatives have diverse therapeutic potential, including neuroprotective, antidiabetic, antioxidant, antimicrobial, anti-inflammatory, anticancer, antihypertensive, and antitubercular activities. The unique electronic and pharmacophoric features of the thiazole ring facilitate specific interactions with various biological targets. This review covers and highlights the most recently reported studies on thiazole-based derivatives with pharmacological potential.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmaceutical Chemistry

Journal Section

Review Article

Authors

Abdüllatif Karakaya
0009-0003-9619-6705
Türkiye

Emine Rana Bağci
0009-0004-7452-0532
Türkiye

Betül Kaya ^*
0000-0002-1713-9485
Türkiye

Ulviye Acar Çevik
0000-0003-1879-1034
Türkiye

Zafer Asım Kaplancıklı
0000-0003-2252-0923
Türkiye

Publication Date

August 31, 2026

Submission Date

April 13, 2026

Acceptance Date

August 13, 2026

Published in Issue

Year 2026 Volume: 5 Number: 2

DOI

https://doi.org/10.55971/EJLS.1929137

IZ

https://izlik.org/JA98NX77DT

Cite

RIS / Bibtex

APA

Karakaya, A., Bağci, E. R., Kaya, B., Acar Çevik, U., & Kaplancıklı, Z. A. (2026). Thiazole: A promising scaffold in medicinal chemistry. European Journal of Life Sciences, 5(2), 53-74. https://doi.org/10.55971/EJLS.1929137

AMA

1.Karakaya A, Bağci ER, Kaya B, Acar Çevik U, Kaplancıklı ZA. Thiazole: A promising scaffold in medicinal chemistry. Eur J Life Sci. 2026;5(2):53-74. doi:10.55971/EJLS.1929137

Chicago

Karakaya, Abdüllatif, Emine Rana Bağci, Betül Kaya, Ulviye Acar Çevik, and Zafer Asım Kaplancıklı. 2026. “Thiazole: A Promising Scaffold in Medicinal Chemistry”. European Journal of Life Sciences 5 (2): 53-74. https://doi.org/10.55971/EJLS.1929137.

EndNote

Karakaya A, Bağci ER, Kaya B, Acar Çevik U, Kaplancıklı ZA (August 1, 2026) Thiazole: A promising scaffold in medicinal chemistry. European Journal of Life Sciences 5 2 53–74.

IEEE

[1]A. Karakaya, E. R. Bağci, B. Kaya, U. Acar Çevik, and Z. A. Kaplancıklı, “Thiazole: A promising scaffold in medicinal chemistry”, Eur J Life Sci, vol. 5, no. 2, pp. 53–74, Aug. 2026, doi: 10.55971/EJLS.1929137.

ISNAD

Karakaya, Abdüllatif - Bağci, Emine Rana - Kaya, Betül - Acar Çevik, Ulviye - Kaplancıklı, Zafer Asım. “Thiazole: A Promising Scaffold in Medicinal Chemistry”. European Journal of Life Sciences 5/2 (August 1, 2026): 53-74. https://doi.org/10.55971/EJLS.1929137.

JAMA

1.Karakaya A, Bağci ER, Kaya B, Acar Çevik U, Kaplancıklı ZA. Thiazole: A promising scaffold in medicinal chemistry. Eur J Life Sci. 2026;5:53–74.

MLA

Karakaya, Abdüllatif, et al. “Thiazole: A Promising Scaffold in Medicinal Chemistry”. European Journal of Life Sciences, vol. 5, no. 2, Aug. 2026, pp. 53-74, doi:10.55971/EJLS.1929137.

Vancouver

1.Abdüllatif Karakaya, Emine Rana Bağci, Betül Kaya, Ulviye Acar Çevik, Zafer Asım Kaplancıklı. Thiazole: A promising scaffold in medicinal chemistry. Eur J Life Sci. 2026 Aug. 1;5(2):53-74. doi:10.55971/EJLS.1929137