Knowledge and behavior of community pharmacists towards detecting drug-drug interactions

Year 2023, Volume: 2 Issue: 1, 39 - 44, 24.04.2023

Fatih Oğuz , Miray Arslan

https://doi.org/10.55971/EJLS.1266042

Abstract

Drug-drug interactions (DDIs) are preventable medication errors that can cause severe adverse effects for patients, which often involve more than one mechanism. Healthcare practitioners, especially community pharmacists, must know and manage potentially significant DDIs to provide patient safety.
This paper mainly aims to determine the knowledge level of community pharmacists about DDIs and to evaluate the behavior of community pharmacists in detecting DDIs. For this aim, a face-to-face questionnaire, including a knowledge assessment test containing 20 drug pairs and ten behavior statements related to detecting DDIs, was applied to community pharmacists.
Seventy-three pharmacists participated in the study. The study’s findings show that the knowledge level of community pharmacists, who are the closest health consultants, about DDIs is relatively low. In addition, responses were found to be moderate in detecting drug interactions.Although statistically significant and positive effects of vocational training on the knowledge level and behaviors of pharmacists were determined, it was revealed that education levels did not have a significant effect.
In this regard, it is essential to improve community pharmacists’ DDI knowledge level through vocational training programs and encourage their interaction-detecting behavior to improve patient outcomes and patient safety.

Keywords

Community Pharmacy, Drug-Drug Interaction, Knowledge, Behavior

References

• Kayaalp SO. Akılcı tedavi yönünden tıbbi farmakoloji. Gözden geçirilmiş 13. Baskı. Ankara: Pelikan Kitabevi; 2012
• Lee A, Stockley I. İlaç yararları ve riskleri. Ankara: Türk Eczacılar Birliği Yayınevi; 2007. 15, İlaç-ilaç etkileşimleri; s.263-280.
• Thanacoody HKN. Section Drug Interactions. Eds. Walker, R. Whittlesea C.Clinical pharmacy and therapeutics. 5th edition, 2012.
• Priyanka S, Vasundara K, Girish K. A comparative study of knowledge, attitude, and practice of drug-drug interactions among interns and nurses in a tertiary care hospital. National Journal of Physiology, Pharmacy and Pharmacology. (2022);12:79-83.https://doi.org/10.4314/tjpr.v10i3.4
• Dahri K, Araujo L, Chen S, Bagri H, Walia K, Lau L, Legal M. Community pharmacist perceptions of drug–drug interactions. Canadian Pharmacists Journal: CPJ. (2023);156(1):42-7.
• Abarca J, Colon LR, Wang VS, Malone DC, Murphy JE, Armstrong EP. Evaluation of the performance of drug-drug interaction screening software in community and hospital pharmacies. Journal of Managed Care Pharmacy.(2006);12:383–9. https://doi.org/10.18553/jmcp.2006.12.5.383
• Chatsisvili A, Sapounidis I, Pavlidou G, Zoumpouridou E, Karakousis VA, Spanakis M, Teperikidis L, Niopas I.Potential drug–drug interactions in prescriptions dispensed in community pharmacies in Greece. Pharmacy world & science. (2011);32:187-193.
• Ko Y, Malone DC, Skrepnek GH, ArmstrongEP, MurphyJE, Abarca J, Rehfeld RA, Reel SJ, Woosley RL. Prescribers’ knowledge of and sources of information )for potential drug-drug interactions. Drug Safety.(2008);31(6):525-536.https://doi.org/10.2165/00002018-200831060-00007
• Saverno KR, Malone DC, Kurowsky J. Pharmacystudents’ ability to identify potential drug-drug interactions. American Journal of Pharmaceutical Education.(2009);73(2):Article 27.
• Rivkin A, Yin H. Evaluation of the role of thec ritical care pharmacist in identifying and avoiding or minimizing significant drug-drug interactions in medical intensive care patients. Journal of criticalcare.(2011);26(1):104.e1-104.e6
• Alrabiah Z, Alhossan A, Alghadeer SM, Wajid S, Babelghaith SD, Al-Arifi MN. Evaluation of community pharmacists’ knowledge about drug–drug interaction in Central SaudiArabia. Saudi Pharmaceutical Journal. (2019);27(4):463-6.
• Abdo MS, Hammad MA, Harun SN, Eusoff TM, Ghadzi SMS. Evaluation of knowledge, attitude and practice of healthcare providers towards life-threatening drug-drug interactions in Penang General Hospital, Malaysia. Clinical Epidemiology and Global Health.(2020);8(4):1253-8.https://doi.org/10.1016/j.cegh.2020.04.023
• Oguz F, Arslan M. Examining and improving senior pharmacy students’ knowledge of clinically critical drug-drug interactions. Pharmacy Education. (2022);22(4):24-31.
• Imam M, Abdel-Sattar RM, AlOmeir O, et al. Assessment of knowledge, attitude, and practice of pharmacists towards drug interactions in Saudi Arabia. J Pharm Res Int. (2021);33:538-45. doi:10.9734/jpri/2021/v33i46b32973 7
• Hamadouk RM, Albashair ED, Mohammed FM, Yousef BA. The Practice of the Community Pharmacists in Managing Potential Drug-Drug Interactions: A Simulated Patient Visits. Integrated Pharmacy Research and Practice, (20222);71-84.
• Makkaoui N, Halaoui A, Atoui Z, et al. Knowledge, attitudes, and practices regarding drug interactions among community pharmacists. J PublicHealth. 2020;29(6):1357–1363.
• Harrington AR, Warholak TL, Hines LE, Taylor AM, Sherrill D, Malone DC. Healthcare professional students’ knowledge of drug-drug interactions. American Journal of Pharmaceutical Education. (2011);75(10):Article 27. https://doi.org/10.5688/ajpe7510199
• Hincapie AL, Warholak TL, Hines LE, Taylor AM, Malone DC. Impact of a drug-drug interaction intervention on pharmacy and medical students’ knowledge and attitudes: a 1-year follow-up. Research in Social and Administrative Pharmacy. (2012);8(5):472-7.https://doi.org/10.1016/j.sapharm.2011.11.003
• Akgöl J, Baltacı N.Evaluation of Knowledge, Attitude and Behavior of Pharmacy Staff About Rational Drug Use. Genel Tıp Dergisi. (2022);32(3);304-9.
• Jose J, Jimmy B, Al-Ghailani ASH, Al Majali MA.A cross sectional pilot study on assessing the knowledge, attitude and behavior of community pharmacists to adverse drug reaction related aspects in the Sultanate of Oman. Saudi pharmaceutical journal. (2014);22(2):163-9.