Case Report

Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes

Volume: 4 Number: 1 January 29, 2025
TR EN

Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes

Abstract

Medication-Related Osteonecrosis of the Jaw (MRONJ) is commonly associated with pharmacological agents like bisphosphonates. However, osteonecrosis can also develop due to other etiologies, including dental trauma and infections. This case report describes osteonecrosis in a 26-year-old male patient who underwent simultaneous implant placement and surgical tooth extraction. The absence of systemic diseases or medication history highlights the role of dental trauma and impaired healing in osteonecrosis development. Management included surgical debridement and antibiotic therapy, consistent with Stage 2 osteonecrosis guidelines. The case emphasizes the importance of minimizing trauma during dental procedures to prevent osteonecrosis, even in younger patients.

Keywords

Ethical Statement

The present study was conducted in accordance with the Declaration of Helsinki.

References

  1. 1. Kılınç, Y. (2024). İlaca Bağlı Çene Osteonekrozu. ADO Klinik Bilimler Dergisi, 13(2), 264-277.
  2. 2. Anastasilakis AD, Pepe J, Napoli N, Palermo A, Magopoulos C, Khan AA, et al. Osteonecrosis of the jaw and antiresorptive agents in benign and malignant diseases: a critical review organized by the ECTS. J Clin Endocrinol Metab. 2022;107(5):1441-60.
  3. 3. Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg. 2003;61(9):1115-7.
  4. 4. Advisory Task Force on Bisphosphonate-Related Osteonecrosis of the Jaws, American Association of Oral and Maxillofacial Surgeons. American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg. 2007;65:369-76.
  5. 5. Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, et al. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw—2014 update. J Oral Maxillofac Surg. 2014;72(10):1938- 56.
  6. 6. Bassir SH, El Kholy K, Chen CY, Lee KH, Intini G. Outcome of early dental implant placement versus other dental implant placement protocols: a systematic review and meta-analysis. J Periodontol. 2019 May;90(5):493-506.
  7. 7. Dahiya M, Dhawan P, Rani S, Saxena V. Critical analysis of the effect of antiresorptive drugs on osteonecrosis associated with dental implants: an umbrella review. Cureus. 2024 Oct 15;16(10):e71506.
  8. 8. Assouline-Dayan Y, Chang C, Greenspan A, Shoenfeld Y, Gershwin ME. Pathogenesis and natural history of osteonecrosis. Semin Arthritis Rheum. 2002;32(2):94-124.

Details

Primary Language

English

Subjects

Surgery (Other)

Journal Section

Case Report

Early Pub Date

January 29, 2025

Publication Date

January 29, 2025

Submission Date

January 3, 2025

Acceptance Date

January 13, 2025

Published in Issue

Year 2025 Volume: 4 Number: 1

APA
Atak Seçen, İ., Mülayim, B., Kurt, B., & Barış, E. (2025). Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes. EurAsian Journal of Oral and Maxillofacial Surgery, 4(1), 7-10. https://izlik.org/JA23XS93ZP
AMA
1.Atak Seçen İ, Mülayim B, Kurt B, Barış E. Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes. EJOMS. 2025;4(1):7-10. https://izlik.org/JA23XS93ZP
Chicago
Atak Seçen, İpek, Berkay Mülayim, Bilgesu Kurt, and Emre Barış. 2025. “Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes”. EurAsian Journal of Oral and Maxillofacial Surgery 4 (1): 7-10. https://izlik.org/JA23XS93ZP.
EndNote
Atak Seçen İ, Mülayim B, Kurt B, Barış E (January 1, 2025) Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes. EurAsian Journal of Oral and Maxillofacial Surgery 4 1 7–10.
IEEE
[1]İ. Atak Seçen, B. Mülayim, B. Kurt, and E. Barış, “Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes”, EJOMS, vol. 4, no. 1, pp. 7–10, Jan. 2025, [Online]. Available: https://izlik.org/JA23XS93ZP
ISNAD
Atak Seçen, İpek - Mülayim, Berkay - Kurt, Bilgesu - Barış, Emre. “Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes”. EurAsian Journal of Oral and Maxillofacial Surgery 4/1 (January 1, 2025): 7-10. https://izlik.org/JA23XS93ZP.
JAMA
1.Atak Seçen İ, Mülayim B, Kurt B, Barış E. Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes. EJOMS. 2025;4:7–10.
MLA
Atak Seçen, İpek, et al. “Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes”. EurAsian Journal of Oral and Maxillofacial Surgery, vol. 4, no. 1, Jan. 2025, pp. 7-10, https://izlik.org/JA23XS93ZP.
Vancouver
1.İpek Atak Seçen, Berkay Mülayim, Bilgesu Kurt, Emre Barış. Osteonecrosis of the Jaw in a Young Patient: Beyond Medication-Related Causes. EJOMS [Internet]. 2025 Jan. 1;4(1):7-10. Available from: https://izlik.org/JA23XS93ZP

Creative Common Attribution Licence, EJOMS Licence © 2024 by Association of Oral and Maxillofacial Surgery Society is licensed under

Creative Commons Attribution–NonCommercial 4.0 International (CC BY-NC 4.0)