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GARRE’NİN SKLEROZAN OSTEOMYELİTİ- NADİR GÖRÜLEN VAKA RAPORU

Year 2025, Volume: 4 Issue: 1, 11 - 14, 29.01.2025

Abstract

Garre osteomiyeliti (GO), bakteriyel odontojenik enfeksiyona bağlı periosteal reaksiyonlar ve yeni kemik oluşumu ile karakterize, nadir görülen kronik inflamatuar bir hastalıktır. Genellikle çocukları ve gençleri etkileyen bu hastalık, mandibula gibi çene kemiklerinde, özellikle premolar ve molar bölgelerde görülür. Klinik olarak genellikle yüz asimetrisi ve çene bölgesinde sert şişlik ile kendini gösterir. "Soğan kabuğu" görünümü olarak bilinen radyografik bulgu, GO için tipiktir.
Bu olgu sunumunda, 10 yaşındaki erkek hastada sağ mandibular birinci molar dişe bağlı olarak gelişen GO tanımlanmıştır. Hastada yüz asimetrisi ve mandibular bölgede sert şişlik gözlenmiş; radyolojik incelemede periosteal reaksiyon ve yeni kemik oluşumu saptanmıştır. Tedavi olarak ilgili diş çekilmiş, antibiyotik tedavisi uygulanmış ve 9 aylık takipte kemik konturlarının normale döndüğü görülmüştür.
GO tedavisinde enfeksiyon kaynağının giderilmesi, antibiyotik tedavisi ve kemik iyileşmesinin desteklenmesi esastır. Çocuklarda erken teşhis ve uygun tedavi, büyüme çağındaki kemik sağlığı için kritik öneme sahiptir. Bu vaka, GO’nun tanı ve tedavisindeki klinik yaklaşımlar için önemli bir örnek teşkil etmektedir.

References

  • 1. Garrè, C. I. Über besondere Formen und Folgezustände der akuten infektiösen Osteomyelitis. Beitrage zur Klinischen Chirurgie, 1893;10, 241–298.
  • 2. Taihi, I., & Radoi, L. Chronic non-suppurative mandibular osteomyelitis with proliferative periostitis: A review. Quintessence Internationa. 2018;49(3), 219–245.
  • 3. Chun, C. S. Y. Chronic recurrent multifocal osteomyelitis of the spine and mandible: Case report and review of the literature. Pediatrics. 2004;113(4), e380–e383.
  • 4. Ambrose, C. G., Kellam, J. F., Crawford, L., & Achor, T. S. Incidence, complications, and novel treatment strategies: Osteomyelitis. In Musculoskeletal Infection 2022; pp. 203–228.
  • 5. Eswar, N. Garre’s osteomyelitis: A case report. Journal of the Indian Society of Pedodontics and Preventive Dentistry. 2001;19, 157–159.
  • 6. Tong, A. C., Ng, I. O., & Yeung, K. A. Osteomyelitis with proliferative periostitis: An unusual case. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 2006;102(5), 14–23.
  • 7. Fukuda, M., Inoue, K., & Sakashita, H. Periostitis ossificans arising in the mandibular bone of a young patient: Report of an unusual case and review of the literature. Journal of Oral and Maxillofacial Surgery. 2017;75(9), 1834-e1–e8.
  • 8. Benca, P. G., Mostofi, R., & Kuo, P. C. Roentgeno-oddities. Oral Surgery, Oral Medicine, Oral Pathology. 1987;63, 258.
  • 9. Brazao-Silva, M. T., & Pinheiro, T. N. The so-called Garrè’s osteomyelitis of jaws and the pivotal utility of computed tomography scan. Contemporary Clinical Dentistry. 2017;8(4), 645–646.
  • 10. Akgül, H. M., Çağlayan, F., Yılmaz, S. G., & Derindağ, G. Garre’s osteomyelitis of the mandible caused by infected tooth. Case Reports in Dentistry. 2018;1(1), 1–4.
  • 11. Suma, R., Vinay, C., Shashikanth, M. C., & Subba Reddy, V. V. Garre’s sclerosing osteomyelitis. Journal of Indian Society of Pedodontics and Preventive Dentistry, Supplement. 2007;30–33.
  • 12. Nortjé, C. J., Wood, R. E., & Grotepass, F. Periostitis ossificans versus Garrè’s osteomyelitis. Oral Surgery, Oral Medicine, Oral Pathology. 1988;66, 249–260.

GARRÉ'S SCLEROSING OSTEOMYELITIS – A RARE CASE REPORT

Year 2025, Volume: 4 Issue: 1, 11 - 14, 29.01.2025

Abstract

Garre's osteomyelitis (GO) is a rare chronic inflammatory disease characterized by periosteal reactions and new bone formation due to bacterial odontogenic infection. This disease, which usually affects children and young people, occurs in the jaw bones such as the mandible, especially in the premolar and molar regions. Clinically, it is characterized by facial asymmetry and hard swelling in the jaw area. The radiographic finding known as “onion skin” appearance is typical for GO.
In this case report, we describe a 10-year-old male patient with GO arising from the right mandibular first molar. Facial asymmetry and hard swelling in the mandibular region were observed; radiologic examination revealed periosteal reaction and new bone formation. The affected tooth was extracted, antibiotic treatment was administered and the bone contours returned to normal after 9 months of follow-up.
Elimination of the source of infection, antibiotic treatment and promotion of bone healing are essential in the treatment of GO. This case is an important example for clinical approaches in the diagnosis and treatment of GO.

References

  • 1. Garrè, C. I. Über besondere Formen und Folgezustände der akuten infektiösen Osteomyelitis. Beitrage zur Klinischen Chirurgie, 1893;10, 241–298.
  • 2. Taihi, I., & Radoi, L. Chronic non-suppurative mandibular osteomyelitis with proliferative periostitis: A review. Quintessence Internationa. 2018;49(3), 219–245.
  • 3. Chun, C. S. Y. Chronic recurrent multifocal osteomyelitis of the spine and mandible: Case report and review of the literature. Pediatrics. 2004;113(4), e380–e383.
  • 4. Ambrose, C. G., Kellam, J. F., Crawford, L., & Achor, T. S. Incidence, complications, and novel treatment strategies: Osteomyelitis. In Musculoskeletal Infection 2022; pp. 203–228.
  • 5. Eswar, N. Garre’s osteomyelitis: A case report. Journal of the Indian Society of Pedodontics and Preventive Dentistry. 2001;19, 157–159.
  • 6. Tong, A. C., Ng, I. O., & Yeung, K. A. Osteomyelitis with proliferative periostitis: An unusual case. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. 2006;102(5), 14–23.
  • 7. Fukuda, M., Inoue, K., & Sakashita, H. Periostitis ossificans arising in the mandibular bone of a young patient: Report of an unusual case and review of the literature. Journal of Oral and Maxillofacial Surgery. 2017;75(9), 1834-e1–e8.
  • 8. Benca, P. G., Mostofi, R., & Kuo, P. C. Roentgeno-oddities. Oral Surgery, Oral Medicine, Oral Pathology. 1987;63, 258.
  • 9. Brazao-Silva, M. T., & Pinheiro, T. N. The so-called Garrè’s osteomyelitis of jaws and the pivotal utility of computed tomography scan. Contemporary Clinical Dentistry. 2017;8(4), 645–646.
  • 10. Akgül, H. M., Çağlayan, F., Yılmaz, S. G., & Derindağ, G. Garre’s osteomyelitis of the mandible caused by infected tooth. Case Reports in Dentistry. 2018;1(1), 1–4.
  • 11. Suma, R., Vinay, C., Shashikanth, M. C., & Subba Reddy, V. V. Garre’s sclerosing osteomyelitis. Journal of Indian Society of Pedodontics and Preventive Dentistry, Supplement. 2007;30–33.
  • 12. Nortjé, C. J., Wood, R. E., & Grotepass, F. Periostitis ossificans versus Garrè’s osteomyelitis. Oral Surgery, Oral Medicine, Oral Pathology. 1988;66, 249–260.
There are 12 citations in total.

Details

Primary Language English
Subjects Surgery (Other)
Journal Section Case Report
Authors

Şevval Mısra Ölmez 0009-0002-6374-8393

Utku Nezih Yılmaz 0000-0002-7794-1744

Early Pub Date January 29, 2025
Publication Date January 29, 2025
Submission Date December 18, 2024
Acceptance Date January 20, 2025
Published in Issue Year 2025 Volume: 4 Issue: 1

Cite

Vancouver Ölmez ŞM, Yılmaz UN. GARRÉ’S SCLEROSING OSTEOMYELITIS – A RARE CASE REPORT. EJOMS. 2025;4(1):11-4.

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