Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps

Uzdan Uz; Kıvanç Günhan; Görkem Eskiizmir

doi:10.5152/ejra.2023.22083

Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps

Abstract

Objective: The aim of this study is to evaluate the relationship between Lund-Mackay scores, osteitis severity, and neutrophil lymphocyte ratio, platelet lymphocyte ratio, basophil lymphocyte ratio, eosinophil lymphocyte ratio, and systemic immune inflammation index in patients with chronic rhinosinusitis with nasal polyps. Methods: Patients who were diagnosed with chronic rhinosinusitis with nasal polyps and underwent endoscopic sinus surgery between 2014 and 2020 were evaluated retrospectively. Lund-Mackay scores and osteitis severity (Hounsfield Unit) were determined separately for each nasal cavity by examining preoperative computed tomography images. Lund-Mackay and Hounsfield Unit scores were compared with the preoperative neutrophil lymphocyte ratio, platelet lymphocyte ratio, basophil lymphocyte ratio, eosinophil lymphocyte ratio, and systemic immune inflammation index. Results: A total of 39 patients (24 males, 15 females) (78 sides) enrolled in the study. There was a positive correlation between right-sided Lund-Mackay scores and ipsilateral Hounsfield Unit (r = 0.343, P = .033). Similarly, there was a positive correlation between left nasal cavity Lund-Mackay scores and ipsilateral Hounsfield Unit (r = 0.376; P=.018). No statistically significant correlation between Lund-Mackay scores and Hounsfield Unit values, and neutrophil lymphocyte ratio, platelet lymphocyte ratio, basophil lymphocyte ratio, eosinophil lymphocyte ratio, and systemic immune inflammation index values were detected. Conclusion: In the present study, no correlation between chronic rhinosinusitis with nasal polyps severity and systematic inflammatory markers was demonstrated.

Keywords

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Research Article

Authors

Uzdan Uz This is me
0000-0001-8973-3590
Türkiye

Kıvanç Günhan
0000-0001-6682-3841
Türkiye

Görkem Eskiizmir
0000-0002-3125-8288
Türkiye

Publication Date

August 28, 2023

Submission Date

November 29, 2022

Acceptance Date

January 29, 2023

Published in Issue

Year 2023 Volume: 6 Number: 2

DOI

https://doi.org/10.5152/ejra.2023.22083

IZ

https://izlik.org/JA96YK63ND

Cite

RIS / Bibtex

APA

Uz, U., Günhan, K., & Eskiizmir, G. (2023). Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps. European Journal of Rhinology and Allergy, 6(2), 42-44. https://doi.org/10.5152/ejra.2023.22083

AMA

1.Uz U, Günhan K, Eskiizmir G. Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps. Eur J Rhinol Allergy. 2023;6(2):42-44. doi:10.5152/ejra.2023.22083

Chicago

Uz, Uzdan, Kıvanç Günhan, and Görkem Eskiizmir. 2023. “Correlation of Disease Severity and Systemic Inflammatory Markers in Patients With Chronic Rhinosinusitis With Nasal Polyps”. European Journal of Rhinology and Allergy 6 (2): 42-44. https://doi.org/10.5152/ejra.2023.22083.

EndNote

Uz U, Günhan K, Eskiizmir G (August 1, 2023) Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps. European Journal of Rhinology and Allergy 6 2 42–44.

IEEE

[1]U. Uz, K. Günhan, and G. Eskiizmir, “Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps”, Eur J Rhinol Allergy, vol. 6, no. 2, pp. 42–44, Aug. 2023, doi: 10.5152/ejra.2023.22083.

ISNAD

Uz, Uzdan - Günhan, Kıvanç - Eskiizmir, Görkem. “Correlation of Disease Severity and Systemic Inflammatory Markers in Patients With Chronic Rhinosinusitis With Nasal Polyps”. European Journal of Rhinology and Allergy 6/2 (August 1, 2023): 42-44. https://doi.org/10.5152/ejra.2023.22083.

JAMA

1.Uz U, Günhan K, Eskiizmir G. Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps. Eur J Rhinol Allergy. 2023;6:42–44.

MLA

Uz, Uzdan, et al. “Correlation of Disease Severity and Systemic Inflammatory Markers in Patients With Chronic Rhinosinusitis With Nasal Polyps”. European Journal of Rhinology and Allergy, vol. 6, no. 2, Aug. 2023, pp. 42-44, doi:10.5152/ejra.2023.22083.

Vancouver

1.Uzdan Uz, Kıvanç Günhan, Görkem Eskiizmir. Correlation of Disease Severity and Systemic Inflammatory Markers in Patients with Chronic Rhinosinusitis with Nasal Polyps. Eur J Rhinol Allergy. 2023 Aug. 1;6(2):42-4. doi:10.5152/ejra.2023.22083