Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis

Hatice Sema Başak; Murat Telli; Yeşim Başal; Çiğdem Yenisey

doi:10.5152/ejra.2021.20036

Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis

Abstract

Objective: We aimed to use middle meatus aspiration technique (MMAT) in both microbiological diagnosis and detection of cytokines and to compare the groups having ARS and non-polyp CRS after determining the microbiological agents and the levels of IL-4, IL-5, IL-13, IL-32, TGF-beta, and thymic stromal lymphopoietin (TSLP). Material and Methods: The patients were classified as ARS and non-polyp CRS. The microbiological samples were grown on 5% defibrinated sheep blood agar, chocolate agar, Eosin-Methylene Blue agar (EMB), and Sabouraud- dextrose agar (SDA) media. IL-4, IL-5, IL-13 IL-32, TLR2, TSLP, and TGF-beta levels of biochemical samples were studied by ELISA method using commercial kits. Results: Samples of nasal discharge were collected in a total of 44 patients. The difference between ARS Group and Non-polyp CRS Group regarding the culture growth of pathogens was statistically significant. The levels of TSLP, TGF-beta, IL-4, IL-5, IL-13 and IL-32 were not in conformity with a normal distribution. The differences between ARS Group and Non-polyp CRS Group were not significant regarding these variable. Conclusion: We have the opinion that, MMAT is a non-invasive method that can be performed at the circumstances of an outpatient clinic and can be used for microbiological diagnosis as well as routine identification of inflammatory processes.

Keywords

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Research Article

Authors

Hatice Sema Başak
0000-0003-0687-975X
Türkiye

Murat Telli
0000-0003-2648-881X
Türkiye

Yeşim Başal
0000-0001-9002-0619
Türkiye

Çiğdem Yenisey
0000-0001-7693-641X
Türkiye

Publication Date

April 1, 2021

Submission Date

February 11, 2021

Acceptance Date

March 16, 2021

Published in Issue

Year 2021 Volume: 4 Number: 1

DOI

https://doi.org/10.5152/ejra.2021.20036

IZ

https://izlik.org/JA94UK77EN

Cite

RIS / Bibtex

APA

Başak, H. S., Telli, M., Başal, Y., & Yenisey, Ç. (2021). Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis. European Journal of Rhinology and Allergy, 4(1), 16-20. https://doi.org/10.5152/ejra.2021.20036

AMA

1.Başak HS, Telli M, Başal Y, Yenisey Ç. Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis. Eur J Rhinol Allergy. 2021;4(1):16-20. doi:10.5152/ejra.2021.20036

Chicago

Başak, Hatice Sema, Murat Telli, Yeşim Başal, and Çiğdem Yenisey. 2021. “Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis”. European Journal of Rhinology and Allergy 4 (1): 16-20. https://doi.org/10.5152/ejra.2021.20036.

EndNote

Başak HS, Telli M, Başal Y, Yenisey Ç (April 1, 2021) Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis. European Journal of Rhinology and Allergy 4 1 16–20.

IEEE

[1]H. S. Başak, M. Telli, Y. Başal, and Ç. Yenisey, “Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis”, Eur J Rhinol Allergy, vol. 4, no. 1, pp. 16–20, Apr. 2021, doi: 10.5152/ejra.2021.20036.

ISNAD

Başak, Hatice Sema - Telli, Murat - Başal, Yeşim - Yenisey, Çiğdem. “Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis”. European Journal of Rhinology and Allergy 4/1 (April 1, 2021): 16-20. https://doi.org/10.5152/ejra.2021.20036.

JAMA

1.Başak HS, Telli M, Başal Y, Yenisey Ç. Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis. Eur J Rhinol Allergy. 2021;4:16–20.

MLA

Başak, Hatice Sema, et al. “Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis”. European Journal of Rhinology and Allergy, vol. 4, no. 1, Apr. 2021, pp. 16-20, doi:10.5152/ejra.2021.20036.

Vancouver

1.Hatice Sema Başak, Murat Telli, Yeşim Başal, Çiğdem Yenisey. Microbiological Factors and Inflammatory Cytokines in Acute and Chronic Rhinosinusitis. Eur J Rhinol Allergy. 2021 Apr. 1;4(1):16-20. doi:10.5152/ejra.2021.20036