Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy

Adnan Ekinci; Hakan Dağıstan; Ahmet Aksoy; Halil Ekinci

doi:10.5152/ejra.2020.297

Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy

Abstract

Objective: This study aimed to compare the serum oxidative stress levels of patients with adenotonsillar hypertrophy (ATH) with those of controls and to investigate the effects of adenotonsillectomy on the oxidative stress levels. Material and Methods: Thirty healthy children (mean age, 6 years) and 30 patients with ATH (mean age, 7 years) aged 2-12 years were included in the study. Serum total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), and paraoxonase (PON) levels were compared between the patient and control groups. The preoperative and postoperative levels were also compared within the patient group. Results: The TOS and OSI levels were significantly higher in the patient group than in the control group (p=0.007 and p=0.027, respectively). There was no significant difference between the patient and control groups in terms of the TAS and PON levels (p=0.399 and p=0.237, respectively). The TOS and OSI levels in the patient group were significantly higher in the preoperative than in the postoperative period (p=0.005 and p=0.023, respectively), whereas there were no significant differences in the TAS and PON levels between the preoperative and postoperative period (p=0.192 and p=0.262, respectively). Conclusion: These findings demonstrate that patients with ATH are exposed to high levels of oxidative stress and that adenotonsillectomy normalizes the oxidative stress.

Keywords

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Research Article

Authors

Adnan Ekinci
0000-0001-7725-8024
Türkiye

Hakan Dağıstan
0000-0003-4717-5337
Türkiye

Ahmet Aksoy
0000-0002-7744-8124
Türkiye

Halil Ekinci
0000-0002-6312-1569
Türkiye

Publication Date

August 1, 2020

Submission Date

May 7, 2020

Acceptance Date

July 2, 2020

Published in Issue

Year 2020 Volume: 3 Number: 2

DOI

https://doi.org/10.5152/ejra.2020.297

IZ

https://izlik.org/JA34BE25JA

Cite

RIS / Bibtex

APA

Ekinci, A., Dağıstan, H., Aksoy, A., & Ekinci, H. (2020). Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy. European Journal of Rhinology and Allergy, 3(2), 34-38. https://doi.org/10.5152/ejra.2020.297

AMA

1.Ekinci A, Dağıstan H, Aksoy A, Ekinci H. Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy. Eur J Rhinol Allergy. 2020;3(2):34-38. doi:10.5152/ejra.2020.297

Chicago

Ekinci, Adnan, Hakan Dağıstan, Ahmet Aksoy, and Halil Ekinci. 2020. “Comparison of Preoperative and Postoperative Antioxidant Levels in Patients With Adenotonsillar Hypertrophy”. European Journal of Rhinology and Allergy 3 (2): 34-38. https://doi.org/10.5152/ejra.2020.297.

EndNote

Ekinci A, Dağıstan H, Aksoy A, Ekinci H (August 1, 2020) Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy. European Journal of Rhinology and Allergy 3 2 34–38.

IEEE

[1]A. Ekinci, H. Dağıstan, A. Aksoy, and H. Ekinci, “Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy”, Eur J Rhinol Allergy, vol. 3, no. 2, pp. 34–38, Aug. 2020, doi: 10.5152/ejra.2020.297.

ISNAD

Ekinci, Adnan - Dağıstan, Hakan - Aksoy, Ahmet - Ekinci, Halil. “Comparison of Preoperative and Postoperative Antioxidant Levels in Patients With Adenotonsillar Hypertrophy”. European Journal of Rhinology and Allergy 3/2 (August 1, 2020): 34-38. https://doi.org/10.5152/ejra.2020.297.

JAMA

1.Ekinci A, Dağıstan H, Aksoy A, Ekinci H. Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy. Eur J Rhinol Allergy. 2020;3:34–38.

MLA

Ekinci, Adnan, et al. “Comparison of Preoperative and Postoperative Antioxidant Levels in Patients With Adenotonsillar Hypertrophy”. European Journal of Rhinology and Allergy, vol. 3, no. 2, Aug. 2020, pp. 34-38, doi:10.5152/ejra.2020.297.

Vancouver

1.Adnan Ekinci, Hakan Dağıstan, Ahmet Aksoy, Halil Ekinci. Comparison of Preoperative and Postoperative Antioxidant Levels in Patients with Adenotonsillar Hypertrophy. Eur J Rhinol Allergy. 2020 Aug. 1;3(2):34-8. doi:10.5152/ejra.2020.297