The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp

Fatma Nur Yıldırım; Yaşar Can Akar; Ceren Günel; Sema Hatice Başak

doi:10.5152/ejra.2020.270

The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp

Abstract

Objective: In recent years, a different subtype, characterized by eosinophilia infiltration that is associated with T-helper cell type 2 (Th2) inflammation is known to worsen disease prognosis in patients with a nasal polyp. We aimed to assess the correlation of serum and tissue eosinophil levels and the radiological severity of the disease in our own patient group. Material and Methods: Total 201 patients, including 131 men and 70 women who had undergone endoscopic sinus surgery for nasal polyp from 2013 to 2017 at the Aydın Adnan Menderes University Hospital were enrolled in our study. The eosinophil rates in the preoperative whole blood hemogram examinations and the rates of eosinophils in surgical pathologies were compared; the paranasal sinus computed tomography (CT) sections were evaluated as per the Lund-Mackey score and Kennedy osteitis score (KOS). Osteitis was scored radiologically as per the KOS systems. As per the tissue eosinophil count, more patients had an eosinophil count >10 eosinophil count/HPF (large magnification; 400×) and fewer had eosinophil count ≤10 eosinophil/HPF count. Results: The Lund-Mackey scores were significantly higher in those with high eosinophil levels in the pathological specimens. The KOS were also found to be high in patients with high Lund-Mackey scores. In patients with higher eosinophil levels in the blood sample, the tissue eosinophil value in pathology samples was also high. Conclusion: In patients with eosinophilia in the tissue or blood, the radiological prevalence and the osteitis scores of chronic sinusitis are expected to be high.

Keywords

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Research Article

Authors

Fatma Nur Yıldırım This is me
Türkiye

Yaşar Can Akar This is me
0000-0002-9033-2206
Türkiye

Ceren Günel
0000-0002-1760-6397
Türkiye

Sema Hatice Başak This is me
0000-0003-0687-975X
Türkiye

Publication Date

August 1, 2020

Submission Date

April 5, 2020

Acceptance Date

July 29, 2020

Published in Issue

Year 2020 Volume: 3 Number: 2

DOI

https://doi.org/10.5152/ejra.2020.270

IZ

https://izlik.org/JA33HF27FJ

Cite

RIS / Bibtex

APA

Yıldırım, F. N., Akar, Y. C., Günel, C., & Başak, S. H. (2020). The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp. European Journal of Rhinology and Allergy, 3(2), 44-48. https://doi.org/10.5152/ejra.2020.270

AMA

1.Yıldırım FN, Akar YC, Günel C, Başak SH. The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp. Eur J Rhinol Allergy. 2020;3(2):44-48. doi:10.5152/ejra.2020.270

Chicago

Yıldırım, Fatma Nur, Yaşar Can Akar, Ceren Günel, and Sema Hatice Başak. 2020. “The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients With a Nasal Polyp”. European Journal of Rhinology and Allergy 3 (2): 44-48. https://doi.org/10.5152/ejra.2020.270.

EndNote

Yıldırım FN, Akar YC, Günel C, Başak SH (August 1, 2020) The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp. European Journal of Rhinology and Allergy 3 2 44–48.

IEEE

[1]F. N. Yıldırım, Y. C. Akar, C. Günel, and S. H. Başak, “The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp”, Eur J Rhinol Allergy, vol. 3, no. 2, pp. 44–48, Aug. 2020, doi: 10.5152/ejra.2020.270.

ISNAD

Yıldırım, Fatma Nur - Akar, Yaşar Can - Günel, Ceren - Başak, Sema Hatice. “The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients With a Nasal Polyp”. European Journal of Rhinology and Allergy 3/2 (August 1, 2020): 44-48. https://doi.org/10.5152/ejra.2020.270.

JAMA

1.Yıldırım FN, Akar YC, Günel C, Başak SH. The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp. Eur J Rhinol Allergy. 2020;3:44–48.

MLA

Yıldırım, Fatma Nur, et al. “The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients With a Nasal Polyp”. European Journal of Rhinology and Allergy, vol. 3, no. 2, Aug. 2020, pp. 44-48, doi:10.5152/ejra.2020.270.

Vancouver

1.Fatma Nur Yıldırım, Yaşar Can Akar, Ceren Günel, Sema Hatice Başak. The Effect of Eosinophilia Levels on the Radiological Severity of the Disease in Patients with a Nasal Polyp. Eur J Rhinol Allergy. 2020 Aug. 1;3(2):44-8. doi:10.5152/ejra.2020.270