Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss

Meltem Bozacı Kılıçoğlu; Bayram Şahin; Levent Aydemir; Gülçin Yeğen; Şenol Çomoğlu

doi:10.5152/ejra.2019.63

Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss

Abstract

Primary nasopharyngeal amyloidosis (PNA) is an extremely rare condition described in the otorhinolaryngology literature, for which the standard therapy still does not exist. Herein, we discuss an atypically presented PNA case that caused a nasopharyngeal mass and the conductive-type hearing loss. A 54-year-old male patient presented with aural fullness and hearing loss in the right ear lasting for 2 weeks. A physical examination with nasal endoscopy indicated an irregular mass lesion on the right half of the nasopharynx. Otomicroscopy showed otitis media with effusion (Type B tympanogram) in the right ear. Magnetic resonance imaging (MRI) revealed the presence of a contrast-enhanced soft tissue mass arising from the lateral nasopharyngeal wall. A biopsy was performed with nasal endoscopy under local anesthesia, and histopathological evaluation was reported as primary (AL type) amyloidosis. Therefore, the patient was accepted as PNA due to the absence of systemic involvement. One year later, the patient was admitted due to hoarseness. A histopathological examination of the right ventricle was reported as primary amyloidosis. PNA is an exceedingly rare condition, and it typically occurs as an isolated manifestation of localized amyloidosis. However, the clinician must be aware of the association with nasopharyngeal carcinoma and the possibility of plasma cell dyscrasias, especially multiple myeloma and lymphoproliferative diseases. In the absence of systemic disease evidence, localized amyloidosis of the nasopharynx and larynx may be treated conservatively.

Keywords

References

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Details

Primary Language

English

Subjects

Otorhinolaryngology

Journal Section

Case Report

Authors

Meltem Bozacı Kılıçoğlu
0000-0001-9952-0329
Türkiye

Bayram Şahin
0000-0002-3886-4432
Türkiye

Levent Aydemir
0000-0002-5836-4304
Türkiye

Gülçin Yeğen This is me
0000-0003-2497-219X
Türkiye

Şenol Çomoğlu
0000-0003-4632-9218
Türkiye

Publication Date

March 6, 2019

Submission Date

December 5, 2018

Acceptance Date

January 21, 2019

Published in Issue

Year 2018 Volume: 1 Number: 3

DOI

https://doi.org/10.5152/ejra.2019.63

IZ

https://izlik.org/JA37ZA82NZ

Cite

RIS / Bibtex

APA

Bozacı Kılıçoğlu, M., Şahin, B., Aydemir, L., Yeğen, G., & Çomoğlu, Ş. (2019). Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss. European Journal of Rhinology and Allergy, 1(3), 79-83. https://doi.org/10.5152/ejra.2019.63

AMA

1.Bozacı Kılıçoğlu M, Şahin B, Aydemir L, Yeğen G, Çomoğlu Ş. Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss. Eur J Rhinol Allergy. 2019;1(3):79-83. doi:10.5152/ejra.2019.63

Chicago

Bozacı Kılıçoğlu, Meltem, Bayram Şahin, Levent Aydemir, Gülçin Yeğen, and Şenol Çomoğlu. 2019. “Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss”. European Journal of Rhinology and Allergy 1 (3): 79-83. https://doi.org/10.5152/ejra.2019.63.

EndNote

Bozacı Kılıçoğlu M, Şahin B, Aydemir L, Yeğen G, Çomoğlu Ş (March 1, 2019) Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss. European Journal of Rhinology and Allergy 1 3 79–83.

IEEE

[1]M. Bozacı Kılıçoğlu, B. Şahin, L. Aydemir, G. Yeğen, and Ş. Çomoğlu, “Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss”, Eur J Rhinol Allergy, vol. 1, no. 3, pp. 79–83, Mar. 2019, doi: 10.5152/ejra.2019.63.

ISNAD

Bozacı Kılıçoğlu, Meltem - Şahin, Bayram - Aydemir, Levent - Yeğen, Gülçin - Çomoğlu, Şenol. “Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss”. European Journal of Rhinology and Allergy 1/3 (March 1, 2019): 79-83. https://doi.org/10.5152/ejra.2019.63.

JAMA

1.Bozacı Kılıçoğlu M, Şahin B, Aydemir L, Yeğen G, Çomoğlu Ş. Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss. Eur J Rhinol Allergy. 2019;1:79–83.

MLA

Bozacı Kılıçoğlu, Meltem, et al. “Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss”. European Journal of Rhinology and Allergy, vol. 1, no. 3, Mar. 2019, pp. 79-83, doi:10.5152/ejra.2019.63.

Vancouver

1.Meltem Bozacı Kılıçoğlu, Bayram Şahin, Levent Aydemir, Gülçin Yeğen, Şenol Çomoğlu. Primary Nasopharyngeal Amyloidosis: Unexpected Cause of Unilateral Hearing Loss. Eur J Rhinol Allergy. 2019 Mar. 1;1(3):79-83. doi:10.5152/ejra.2019.63