Letter to Editor

Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers

Volume: 7 Number: 2 August 31, 2025

Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers

Abstract

This letter offers a critical yet appreciative perspective on the recent case report exploring the Tp-e/QTc ratio and blood lactate levels as early indicators of cardiac ischemia in carbon monoxide poisoning. While acknowledging the clinical relevance of the proposed markers, we suggest enriching the discussion with additional context on electrophysiological mechanisms, reference values, and patient outcomes. We commend the authors for drawing attention to an often-overlooked diagnostic challenge and highlight the need for future prospective validation.

Keywords

References

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  5. Zhao X, Xie Z, Chu Y, Yang L, Xu W, Yang X, et al. Association between Tp-e/QT ratio and prognosis in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Clin Cardiol. 2012;35(9):559-64. doi: 10.1002/clc.22022.
  6. Haliga RE, Morărașu BC, Șorodoc V, Lionte C, Sîrbu O, Stoica A, et al. Rare Causes of Acute Coronary Syndrome: Carbon Monoxide Poisoning. Life (Basel). 2022;12(8):1158. doi: 10.3390/life12081158.
  7. Henry CR, Satran D, Lindgren B, et al. Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning. JAMA. 2006;295(4):398–402. https://doi.org/10.1001/jama.295.4.398.
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Details

Primary Language

English

Subjects

Emergency Medicine

Journal Section

Letter to Editor

Publication Date

August 31, 2025

Submission Date

May 27, 2025

Acceptance Date

June 16, 2025

Published in Issue

Year 2025 Volume: 7 Number: 2

APA
Aslan, R., Zeytun, N., & Ardahanlı, İ. (2025). Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers. Eurasian Journal of Toxicology, 7(2), 19-20. https://doi.org/10.51262/ejtox.1695357
AMA
1.Aslan R, Zeytun N, Ardahanlı İ. Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers. Eurasian J Tox. 2025;7(2):19-20. doi:10.51262/ejtox.1695357
Chicago
Aslan, Ramazan, Nurdan Zeytun, and İsa Ardahanlı. 2025. “Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-E QTc and Lactate As Early Markers”. Eurasian Journal of Toxicology 7 (2): 19-20. https://doi.org/10.51262/ejtox.1695357.
EndNote
Aslan R, Zeytun N, Ardahanlı İ (August 1, 2025) Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers. Eurasian Journal of Toxicology 7 2 19–20.
IEEE
[1]R. Aslan, N. Zeytun, and İ. Ardahanlı, “Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers”, Eurasian J Tox, vol. 7, no. 2, pp. 19–20, Aug. 2025, doi: 10.51262/ejtox.1695357.
ISNAD
Aslan, Ramazan - Zeytun, Nurdan - Ardahanlı, İsa. “Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-E QTc and Lactate As Early Markers”. Eurasian Journal of Toxicology 7/2 (August 1, 2025): 19-20. https://doi.org/10.51262/ejtox.1695357.
JAMA
1.Aslan R, Zeytun N, Ardahanlı İ. Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers. Eurasian J Tox. 2025;7:19–20.
MLA
Aslan, Ramazan, et al. “Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-E QTc and Lactate As Early Markers”. Eurasian Journal of Toxicology, vol. 7, no. 2, Aug. 2025, pp. 19-20, doi:10.51262/ejtox.1695357.
Vancouver
1.Ramazan Aslan, Nurdan Zeytun, İsa Ardahanlı. Broadening the Diagnostic Horizon in Carbon Monoxide Poisoning: Reflections on Tp-e/QTc and Lactate as Early Markers. Eurasian J Tox. 2025 Aug. 1;7(2):19-20. doi:10.51262/ejtox.1695357

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