Antiviral Drugs and Their Toxicities

Abstract

            Developments in antiviral agents have led to significant progress in the treatment of infections caused by herpes simplex virus 1-2, varicella-zoster virus (VZV), cytomegalovirus, influenza A and B, and human immunodeficiency virus (HIV). There are several antiviral drug therapies that are widely used today. These antiviral drugs are examined under four main headings: drugs effective against influenza viruses, drugs effective against herpes viruses, anti-HIV drugs and immunomodulators in antiviral therapy. Toxicities of these drugs are also examined in four main headings: toxicity of drugs that are effective against herpes viruses, toxicity of drugs effective against influenza viruses, toxicity of antiretroviral drugs and toxicity of other antiviral agents. Under these main headings, antiviral drugs and toxicities of these drugs will be analyzed in more detail. The side effects and toxicities of these drugs should be well known and if such a situation is encountered, it would be more appropriate to choose another antiviral treatment that may have less side effects and toxicity for the patient if necessary.

Keywords

• Antiviral drugs,side effects,toxicity

Abstract

Antiviral ajanlardaki gelişmeler, herpes simpleks virüs 1-2, varisella-zoster virüs, sitomegalovirüs, influenza A ve B ve insan immün yetmezlik (HIV) virüsükaynaklı enfeksiyonların tedavisinde önemli ilerleme sağlamıştır. Günümüzde yaygın olarak kullanılan çeşitli antiviral ilaç tedavileri vardır. Bu antiviral ilaçlardört ana başlık altında incelenir: influenza virüslerine karşı etkili ilaçlar, herpes virüslerine karşı etkili ilaçlar, anti-HIV ilaçları ve antiviral tedavide kullanılanimmünomodülatörler. Bu ilaçların toksisiteleri ayrıca dört ana başlıkta incelenmiştir: herpes virüslerine karşı etkili ilaçların toksisitesi, influenza virüslerinekarşı etkili ilaçların toksisitesi, antiretroviral ilaçların toksisitesi ve diğer antiviral ajanların toksisitesi. Bu derlemerde, ana başlıklar altında, antiviral ilaçlarve bu ilaçların toksisiteleri daha ayrıntılı olarak analiz edilecektir. Bu ilaçların yan etkileri ve toksisiteleri iyi bilinmeli ve eğer böyle bir durumla karşılaşılırsa,gerekirse hasta için daha az yan etkisi ve toksisitesi olabilecek başka bir antiviral tedavi seçmek daha uygun olacaktır.

Keywords

• Antiviral ilaçlar,yan etki,toksisite

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