Review Article

Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment

Volume: 8 Number: 3 December 26, 2025

Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment

Abstract

Chemotherapy has been an important part of cancer treatment for many years. However, its efficacy is often limited because conventional chemotherapy can cause serious side effects and lead to differences in treatment response between patients. At this point, personalized medicine offers a new approach to eliminating these problems in cancer treatment. Personalized medicine proposes organizing treatment according to the genetic and molecular characteristics of both the tumor and the patient with tailored treatment regimens. Through molecular profiling of the patient and the tumor, oncologists can have a preliminary idea about the most effective drug, allowing them to adjust the treatment specifically for the individual and minimize the harmful effects on healthy tissues. Advances in genomics and precision oncology, and also new platforms such as organoids and organ-on-chips, have made it possible to select drugs, based on tumor-specific biomarkers, genomic alterations, and pharmacogenomic variants. However, there are still some challenges in applying personalized chemotherapy. The main reasons are concerns about the reliability of biomarkers, integration of genomic data into clinical practice, cost-effectiveness, and ethical issues related to genetic privacy. This review summarizes the basic concepts of tumor biology and chemotherapy and discusses how personalized medicine and precision oncology are changing cancer treatment.

Keywords

References

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Details

Primary Language

English

Subjects

Pharmaceutical Sciences, Clinical Pharmacology and Therapeutics, Clinical Sciences (Other)

Journal Section

Review Article

Authors

İmge Kunter *
Kuzey Kıbrıs Türk Cumhuriyeti

Early Pub Date

February 11, 2026

Publication Date

December 26, 2025

Submission Date

December 5, 2025

Acceptance Date

December 19, 2025

Published in Issue

Year 2025 Volume: 8 Number: 3

APA
Kunter, İ. (2025). Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment. EMU Journal of Pharmaceutical Sciences, 8(3), 169-178. https://doi.org/10.54994/emujpharmsci.1836760
AMA
1.Kunter İ. Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment. EMUJPharmSci. 2025;8(3):169-178. doi:10.54994/emujpharmsci.1836760
Chicago
Kunter, İmge. 2025. “Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment”. EMU Journal of Pharmaceutical Sciences 8 (3): 169-78. https://doi.org/10.54994/emujpharmsci.1836760.
EndNote
Kunter İ (December 1, 2025) Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment. EMU Journal of Pharmaceutical Sciences 8 3 169–178.
IEEE
[1]İ. Kunter, “Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment”, EMUJPharmSci, vol. 8, no. 3, pp. 169–178, Dec. 2025, doi: 10.54994/emujpharmsci.1836760.
ISNAD
Kunter, İmge. “Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment”. EMU Journal of Pharmaceutical Sciences 8/3 (December 1, 2025): 169-178. https://doi.org/10.54994/emujpharmsci.1836760.
JAMA
1.Kunter İ. Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment. EMUJPharmSci. 2025;8:169–178.
MLA
Kunter, İmge. “Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment”. EMU Journal of Pharmaceutical Sciences, vol. 8, no. 3, Dec. 2025, pp. 169-78, doi:10.54994/emujpharmsci.1836760.
Vancouver
1.İmge Kunter. Chemotherapy and Personalized Medicine: New Approaches in Modern Cancer Treatment. EMUJPharmSci. 2025 Dec. 1;8(3):169-78. doi:10.54994/emujpharmsci.1836760