Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin

Diatri Nari Ratih; Henytaria Fajrianti; Nunuk Purwanti; Silva Eliana Aspriyanti

doi:10.26650/eor.20251575429

Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin

Abstract

Purpose

This study aimed to evaluate the effects of three final irrigation solutions with chelation properties [ethylenediaminetetraacetic acid (EDTA), novel silver citrate (NSC), and nanochitosan] on root canal dentin erosion and mineral content (calcium-to-phosphorus ratio (Ca/P ratio).

Materials and Methods

A total of 28 premolars were used and assigned to four groups (n = 7): Group 1: 17% EDTA; Group 2: NSC; Group 3: 0.2% nanochitosan; Group 4: saline (control). Each group was finally irrigated with a volume of 1 ml/min until the total final irrigation was performed for 5 min using a 30-gauge side vented needle, and the needle was inserted 1 mm shorter than the working length. Irrigation solution pH was netral. Each tooth was then divided into two parts: mesial and distal. The mesial section was evaluated for root canal dentin erosion, whereas the distal section was analyzed for the Ca/P ratio. Each section was evaluated at three levels (coronal, middle, and apical) of the root canal. Data on root canal erosion were analyzed using the Kruskal-Wallis and Mann-Whitney U tests, whereas the Ca/P ratio was analyzed using one-way ANOVA and Tukey’s test.

Results

The EDTA-treated group exhibited the highest erosion, whereas the nanochitosan-treated group exhibited the lowest erosion of the root canal dentin (p<0.05). The nanochitosan-treated group exhibited the highest Ca/P ratio, whereas the EDTA-treated group exhibited the lowest ratio (p<0.05). The apical level had the highest Ca/P ratio but the lowest erosion compared with the other levels (p<0.05).

Conclusion

Nanochitosan demonstrated the lowest erosion and highest Ca/P ratio at all root canal dentin levels. Therefore, nanochitosan can potentially be used as a final irrigation solution.

Keywords

References

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Details

Primary Language

English

Subjects

Endodontics

Journal Section

Research Article

Authors

Diatri Nari Ratih ^*
0000-0001-5584-1403
Indonesia

Henytaria Fajrianti
0000-0002-2912-6745
Indonesia

Nunuk Purwanti
0009-0001-4360-6358
Indonesia

Silva Eliana Aspriyanti
0000-0002-1425-5755
Indonesia

Publication Date

April 29, 2026

Submission Date

October 29, 2024

Acceptance Date

February 25, 2025

Published in Issue

Year 2026 Number: 1

DOI

https://doi.org/10.26650/eor.20251575429

IZ

https://izlik.org/JA98CK37RH

Cite

RIS / Bibtex

APA

Ratih, D. N., Fajrianti, H., Purwanti, N., & Aspriyanti, S. E. (2026). Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin. European Oral Research, 1, 38-44. https://doi.org/10.26650/eor.20251575429

AMA

1.Ratih DN, Fajrianti H, Purwanti N, Aspriyanti SE. Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin. EOR. 2026;(1):38-44. doi:10.26650/eor.20251575429

Chicago

Ratih, Diatri Nari, Henytaria Fajrianti, Nunuk Purwanti, and Silva Eliana Aspriyanti. 2026. “Effects of Three Final Irrigation Solutions With Chelation Properties on the Erosion and Mineral Content of Root Canal Dentin”. European Oral Research, no. 1: 38-44. https://doi.org/10.26650/eor.20251575429.

EndNote

Ratih DN, Fajrianti H, Purwanti N, Aspriyanti SE (April 1, 2026) Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin. European Oral Research 1 38–44.

IEEE

[1]D. N. Ratih, H. Fajrianti, N. Purwanti, and S. E. Aspriyanti, “Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin”, EOR, no. 1, pp. 38–44, Apr. 2026, doi: 10.26650/eor.20251575429.

ISNAD

Ratih, Diatri Nari - Fajrianti, Henytaria - Purwanti, Nunuk - Aspriyanti, Silva Eliana. “Effects of Three Final Irrigation Solutions With Chelation Properties on the Erosion and Mineral Content of Root Canal Dentin”. European Oral Research. 1 (April 1, 2026): 38-44. https://doi.org/10.26650/eor.20251575429.

JAMA

1.Ratih DN, Fajrianti H, Purwanti N, Aspriyanti SE. Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin. EOR. 2026;:38–44.

MLA

Ratih, Diatri Nari, et al. “Effects of Three Final Irrigation Solutions With Chelation Properties on the Erosion and Mineral Content of Root Canal Dentin”. European Oral Research, no. 1, Apr. 2026, pp. 38-44, doi:10.26650/eor.20251575429.

Vancouver

1.Diatri Nari Ratih, Henytaria Fajrianti, Nunuk Purwanti, Silva Eliana Aspriyanti. Effects of three final irrigation solutions with chelation properties on the erosion and mineral content of root canal dentin. EOR. 2026 Apr. 1;(1):38-44. doi:10.26650/eor.20251575429