Research Article

Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study

Volume: 60 Number: 1 September 7, 2026
  • Sahar Kadri *
  • Eya Moussaoui
  • Asma Ben Cheikh
  • Lamia Oualha

Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study

Abstract

Purpose

The aim of this study was to evaluate the concordance between the histopathological diagnoses obtained from biopsies of maxillofacial lesions and the definitive histopathological diagnoses of the excised specimens, and to identify factors associated with diagnostic discordance.

Subjects and methods

A retrospective cross-sectional study was conducted on 203 patients with maxillofacial lesions who underwent surgical excision following biopsy between 2005 and 2019. Sociodemographic, clinical, and histopathological data were collected and analyzed. Biopsy diagnoses were compared with the final excision diagnoses using Cohen’s kappa coefficient and appropriate statistical tests.

Results

The histopathological diagnosis of the excised specimen was consistent with the biopsy diagnosis in 87.8% of cases (p = 0.001). No significant differences were found between biopsy and excision diagnoses when the biopsy was performed by a specialist or a resident (p = 0.29), or when the histopathological evaluation was conducted by a resident or a specialist pathologist (p = 0.59). Likewise, no significant differences were observed according to whether the biopsy specimen consisted of a single fragment or multiple fragments (p = 0.65).

Conclusion

Careful identification and management of factors contributing to diagnostic discordance may improve the reliability of biopsy diagnoses and consequently enhance patient management.

Keywords

Supporting Institution

None

Ethical Statement

The collection and use of data complied with institutional and international ethical standards, ensuring full protection of patient anonymity and data confidentiality. The study protocol was reviewed and approved by the Ethical Committee of the Faculty of Dental Medicine of Monastir, Tunisia (Approval No. 2025018).

Thanks

We thank the editorial board and reviewers in advance for their time and consideration of our manuscript.

References

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Details

Primary Language

English

Subjects

Oral and Maxillofacial Surgery

Journal Section

Research Article

Publication Date

September 7, 2026

Submission Date

November 27, 2025

Acceptance Date

April 11, 2026

Published in Issue

Year 2026 Volume: 60 Number: 1

APA
Kadri, S., Moussaoui, E., Ben Cheikh, A., & Oualha, L. (2026). Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study. European Oral Research, 60(1), 240-245. https://doi.org/10.26650/eor.1829734
AMA
1.Kadri S, Moussaoui E, Ben Cheikh A, Oualha L. Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study. EOR. 2026;60(1):240-245. doi:10.26650/eor.1829734
Chicago
Kadri, Sahar, Eya Moussaoui, Asma Ben Cheikh, and Lamia Oualha. 2026. “Diagnostic Concordance Between Incisional Biopsies and Final Excision Specimens in Maxillofacial Lesions: A 14-Year Retrospective Study”. European Oral Research 60 (1): 240-45. https://doi.org/10.26650/eor.1829734.
EndNote
Kadri S, Moussaoui E, Ben Cheikh A, Oualha L (September 1, 2026) Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study. European Oral Research 60 1 240–245.
IEEE
[1]S. Kadri, E. Moussaoui, A. Ben Cheikh, and L. Oualha, “Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study”, EOR, vol. 60, no. 1, pp. 240–245, Sept. 2026, doi: 10.26650/eor.1829734.
ISNAD
Kadri, Sahar - Moussaoui, Eya - Ben Cheikh, Asma - Oualha, Lamia. “Diagnostic Concordance Between Incisional Biopsies and Final Excision Specimens in Maxillofacial Lesions: A 14-Year Retrospective Study”. European Oral Research 60/1 (September 1, 2026): 240-245. https://doi.org/10.26650/eor.1829734.
JAMA
1.Kadri S, Moussaoui E, Ben Cheikh A, Oualha L. Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study. EOR. 2026;60:240–245.
MLA
Kadri, Sahar, et al. “Diagnostic Concordance Between Incisional Biopsies and Final Excision Specimens in Maxillofacial Lesions: A 14-Year Retrospective Study”. European Oral Research, vol. 60, no. 1, Sept. 2026, pp. 240-5, doi:10.26650/eor.1829734.
Vancouver
1.Sahar Kadri, Eya Moussaoui, Asma Ben Cheikh, Lamia Oualha. Diagnostic concordance between incisional biopsies and final excision specimens in maxillofacial Lesions: a 14-Year retrospective study. EOR. 2026 Sep. 1;60(1):240-5. doi:10.26650/eor.1829734