Research Article

Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration

Volume: 60 Number: 1 September 9, 2026

Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration

Abstract

Purpose

The aim is to evaluate and compare the effects of single versus repeated applications of potassium iodide (KI) on SDF-induced discoloration in primary canines.

Materials and Methods

Thirty-six extracted human primary canines with dentinal caries were randomly allocated into three groups: Group I received 38% SDF alone; Group II received SDF followed by a single KI application; and Group III received SDF followed by immediately application after SDF and repeated on days 1, 3, and 5. Color change (ΔE) was assessed on Days 1, 14, and 30 using a spectrophotometer based on the CIE Lab* system. Statistical analysis included One-Way ANOVA with Tukey post hoc tests for between-group comparisons, and Repeated Measures ANOVA with Bonferroni adjustment for within-group comparisons.

Results

All groups showed significant differences in ΔE values at each time point, except between the single and repeated KI groups on Day 1. The Group I exhibited the highest ΔE values throughout the study, indicating the greatest discoloration, while Group III resulted in the lowest values. Over time, a progressive increase in discoloration was observed in Groups II, whereas partial color stability was maintained in Group III.

Conclusion

Repeated application of KI after SDF treatment can result in a higher reduction in tooth discoloration compared to a single-application. This protocol may enhance the clinical acceptability of SDF, especially for visible anterior teeth in pediatric patients.

Keywords

References

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Details

Primary Language

English

Subjects

Paedodontics

Journal Section

Research Article

Publication Date

September 9, 2026

Submission Date

December 20, 2025

Acceptance Date

May 2, 2026

Published in Issue

Year 2026 Volume: 60 Number: 1

APA
Hajiahmadi, M., & Sadighbatha, S. (2026). Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration. European Oral Research, 60(1), 305-311. https://doi.org/10.26650/eor.20261845757
AMA
1.Hajiahmadi M, Sadighbatha S. Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration. EOR. 2026;60(1):305-311. doi:10.26650/eor.20261845757
Chicago
Hajiahmadi, Maryam, and Samira Sadighbatha. 2026. “Effect of a Clinically Feasible Repeated Potassium Iodide Application Protocol on Silver Diamine Fluoride–induced Discoloration”. European Oral Research 60 (1): 305-11. https://doi.org/10.26650/eor.20261845757.
EndNote
Hajiahmadi M, Sadighbatha S (September 9, 2026) Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration. European Oral Research 60 1 305–311.
IEEE
[1]M. Hajiahmadi and S. Sadighbatha, “Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration”, EOR, vol. 60, no. 1, pp. 305–311, Sept. 2026, doi: 10.26650/eor.20261845757.
ISNAD
Hajiahmadi, Maryam - Sadighbatha, Samira. “Effect of a Clinically Feasible Repeated Potassium Iodide Application Protocol on Silver Diamine Fluoride–induced Discoloration”. European Oral Research 60/1 (September 9, 2026): 305-311. https://doi.org/10.26650/eor.20261845757.
JAMA
1.Hajiahmadi M, Sadighbatha S. Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration. EOR. 2026;60:305–311.
MLA
Hajiahmadi, Maryam, and Samira Sadighbatha. “Effect of a Clinically Feasible Repeated Potassium Iodide Application Protocol on Silver Diamine Fluoride–induced Discoloration”. European Oral Research, vol. 60, no. 1, Sept. 2026, pp. 305-11, doi:10.26650/eor.20261845757.
Vancouver
1.Maryam Hajiahmadi, Samira Sadighbatha. Effect of a clinically feasible repeated potassium iodide application protocol on silver diamine fluoride–induced discoloration. EOR. 2026 Sep. 9;60(1):305-11. doi:10.26650/eor.20261845757