Yıl 2019, Cilt 7 , Sayı , Sayfalar 204 - 211 2019-11-24

Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry

Asmaa M. AL-HASANY [1] , Amer Th. AL-TAEE [2] , Haitham A. AL-WAHB [3]


In this work, the interaction between theophylline (TP) and creatinine was studied. A three electrode detection system was used, 2mm diameter glassy carbon electrode as working electrode, 1mm diameter platinum wire as auxillary electrode and Ag/AgCl. saturated KCl as reference electrode. Square wave voltammetric technique (SWV) also used, the voltammogram of theophylline shows a stable well - defined reduction peak at (1.07) V versus Ag/ AgCl Sat. KCl/ in phosphate buffer solution (pH=7) using glassy carbon electrode. The voltammograms were recorded for theophyline with serious addition of creatinine, interaction of theophyline with the sequence addition of creatinine were examined at different temperatures (288, 293, 298, 298, 303, 308 and 310) ºK and the thermodynamics parameters were calculated. The binding constant (K) between theophylene and creatinine was also measured. The results showed that the binding constant (K) decreased with increasing temperature, this is as a result of the negative value of enthalpy change ( -46.6 ) KJ. mol-1 ( exothermic binding ). Negative value of Gibbs energy (-275.338 x 102 _ -36384.961 x102) KJ. mol-1 indicates that the interaction is spontaneous and could be due to van der waals forces or hydrogen bonds effect i. e the low value of Gibbs energy indicates weak interaction between the studied compounds.
Theophylline, Cratinine, Interaction, Modified electrode
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Konular Mühendislik
Bölüm Makaleler
Yazarlar

Yazar: Asmaa M. AL-HASANY
Kurum: University of Mosul
Ülke: Iraq


Yazar: Amer Th. AL-TAEE
Kurum: University of Mosul
Ülke: Iraq


Yazar: Haitham A. AL-WAHB
Kurum: University of Mosul
Ülke: Iraq


Tarihler

Yayımlanma Tarihi : 24 Kasım 2019

Bibtex @araştırma makalesi { epstem655396, journal = {The Eurasia Proceedings of Science Technology Engineering and Mathematics}, issn = {}, eissn = {2602-3199}, address = {isresoffice@gmail.com}, publisher = {ISRES Organizasyon Turizm Eğitim Danışmanlık Ltd. Şti.}, year = {2019}, volume = {7}, pages = {204 - 211}, doi = {}, title = {Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry}, key = {cite}, author = {AL-HASANY, Asmaa M. and AL-TAEE, Amer Th. and AL-WAHB, Haitham A.} }
APA AL-HASANY, A , AL-TAEE, A , AL-WAHB, H . (2019). Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry. The Eurasia Proceedings of Science Technology Engineering and Mathematics , 7 () , 204-211 . Retrieved from https://dergipark.org.tr/tr/pub/epstem/issue/50288/655396
MLA AL-HASANY, A , AL-TAEE, A , AL-WAHB, H . "Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 204-211 <https://dergipark.org.tr/tr/pub/epstem/issue/50288/655396>
Chicago AL-HASANY, A , AL-TAEE, A , AL-WAHB, H . "Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 204-211
RIS TY - JOUR T1 - Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry AU - Asmaa M. AL-HASANY , Amer Th. AL-TAEE , Haitham A. AL-WAHB Y1 - 2019 PY - 2019 N1 - DO - T2 - The Eurasia Proceedings of Science Technology Engineering and Mathematics JF - Journal JO - JOR SP - 204 EP - 211 VL - 7 IS - SN - -2602-3199 M3 - UR - Y2 - 2020 ER -
EndNote %0 The Eurasia Proceedings of Science Technology Engineering and Mathematics Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry %A Asmaa M. AL-HASANY , Amer Th. AL-TAEE , Haitham A. AL-WAHB %T Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry %D 2019 %J The Eurasia Proceedings of Science Technology Engineering and Mathematics %P -2602-3199 %V 7 %N %R %U
ISNAD AL-HASANY, Asmaa M. , AL-TAEE, Amer Th. , AL-WAHB, Haitham A. . "Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 / (Kasım 2019): 204-211 .
AMA AL-HASANY A , AL-TAEE A , AL-WAHB H . Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry. EPSTEM. 2019; 7: 204-211.
Vancouver AL-HASANY A , AL-TAEE A , AL-WAHB H . Electrochemical Study of Theophylline-Creatinine Interaction Using Square Wave Voltammetry. The Eurasia Proceedings of Science Technology Engineering and Mathematics. 2019; 7: 211-204.