Yıl 2019, Cilt 7 , Sayı , Sayfalar 236 - 248 2019-11-24

Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry

Amer Th. AL-TAEE [1] , Aws Z. AL-HAFIDH [2]


In this work an electrochemical quantification and interaction of valsartan and glimepiride were studied on hanging mercury drop electrode (HMDE) using square wave voltammetric (SWV) technique. The effect of temperature on the interaction was investigated in eight degrees of heat and the thermodynamics parameters (enthalpy, entropy & free gibbs energy) were calculated for the interaction using Van't Hoff equation and binding constant (K) also obtained from interaction equation. From the values of the calculated thermodynamic parameters it found that the main bonding forces that predominated over the interaction were Vander Waals and Hydrogen bonding. The calibration curves of each drug was liner with R2 value equal to 0.9819, 0.997 and the limit of detection was found to be 4.99 x 10-7, 3.48 x 10-8 for valsartan and glimepiride respectively. Through the limit of detection, this method can be used as a standard method in estimating the pharmacists in pharmaceutics and verifying the credibility of the manufacturers of the two drugs.
Square wave voltammetry (SWV), Valsartan, Glimepiride, Drug interaction
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Birincil Dil en
Konular Mühendislik
Bölüm Makaleler
Yazarlar

Yazar: Amer Th. AL-TAEE
Kurum: Mosul University
Ülke: Iraq


Yazar: Aws Z. AL-HAFIDH
Kurum: Mosul University
Ülke: Iraq


Tarihler

Yayımlanma Tarihi : 24 Kasım 2019

Bibtex @araştırma makalesi { epstem655437, journal = {The Eurasia Proceedings of Science Technology Engineering and Mathematics}, issn = {}, eissn = {2602-3199}, address = {isresoffice@gmail.com}, publisher = {ISRES Organizasyon Turizm Eğitim Danışmanlık Ltd. Şti.}, year = {2019}, volume = {7}, pages = {236 - 248}, doi = {}, title = {Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry}, key = {cite}, author = {AL-TAEE, Amer Th. and AL-HAFIDH, Aws Z.} }
APA AL-TAEE, A , AL-HAFIDH, A . (2019). Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry. The Eurasia Proceedings of Science Technology Engineering and Mathematics , 7 () , 236-248 . Retrieved from https://dergipark.org.tr/tr/pub/epstem/issue/50288/655437
MLA AL-TAEE, A , AL-HAFIDH, A . "Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 236-248 <https://dergipark.org.tr/tr/pub/epstem/issue/50288/655437>
Chicago AL-TAEE, A , AL-HAFIDH, A . "Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 236-248
RIS TY - JOUR T1 - Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry AU - Amer Th. AL-TAEE , Aws Z. AL-HAFIDH Y1 - 2019 PY - 2019 N1 - DO - T2 - The Eurasia Proceedings of Science Technology Engineering and Mathematics JF - Journal JO - JOR SP - 236 EP - 248 VL - 7 IS - SN - -2602-3199 M3 - UR - Y2 - 2020 ER -
EndNote %0 The Eurasia Proceedings of Science Technology Engineering and Mathematics Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry %A Amer Th. AL-TAEE , Aws Z. AL-HAFIDH %T Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry %D 2019 %J The Eurasia Proceedings of Science Technology Engineering and Mathematics %P -2602-3199 %V 7 %N %R %U
ISNAD AL-TAEE, Amer Th. , AL-HAFIDH, Aws Z. . "Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 / (Kasım 2019): 236-248 .
AMA AL-TAEE A , AL-HAFIDH A . Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry. EPSTEM. 2019; 7: 236-248.
Vancouver AL-TAEE A , AL-HAFIDH A . Electrochemical Behavior of Valsartan, Glimepiride and Their Interaction with Each Other Using Square Wave Voltammetry. The Eurasia Proceedings of Science Technology Engineering and Mathematics. 2019; 7: 248-236.