Yıl 2019, Cilt 7 , Sayı , Sayfalar 385 - 390 2019-11-24

Spectrophotometric Determination of Sulfacetamide

Zena TALAL [1] , Wadala A. BASHIR [2]


Sulfacetamide is a sulfonamide antibiotic that is used as a cream to treat skin infections and as eye drops infections. On the skin it is used to treat acne and seborrheic dermatitis. In Sulfacetamide Sodium is the sodium salt of sulfacetamide, a synthetic sulfanyl acetamide derivative with bacteriostatic activity. Sulfacetamide [ N ( 4 – aminophenyl ) sulphonyl ] acetamide is a N – subistituted derivatives of sulfanilamide which is widely used in the treatment of urinary tract infection and burn therapy. A spectrophotometric method for the determination of trace amounts of sulfacetamide, based on coupling of diazotized sulfacetamide with m- aminophenol to form an intense orange coloured, water soluble monoazo dye which exhibits maximum absorption at 436 nm. Adherence to Beer`s law is observed over the concentration range ( 0.4 – 8 ) ppm with a molar absorptivity of ( 1.68 × 104 ) mol-1. Cm-1, Sandell sensitivity index of ( 1.4 × 104 ) mg.cm-2, precision of ( +- 0.28 - +- 0.8 ) and accuracy of ( 0 – 0.3 ) indicating that the method is accurate and precise. the proposed method has been successfully applied to the assay of sulfacetamide eye drops.
Sulfacetamide, N (4 – aminophenyl ) sulphonyl, acetamide, Diazotized, Eye drops
  • British Pharmacopeia on CD-Rom ;(2013), 7th Edn., System Simulation Ltd. The stationary office, London. Wilson and Gisvold"text book of organic medicinal and pharmaceutical chemistry", 8th edn., J.B.Liippincott company, New York, (1982), 629-630. Kucers A and Mck bennett N., "the use of antibiotics", 3rd edn. , Lowe and Brydone.(printers) ltd., london, (1979), 657-659. Budavari S., O'Neil,J.M., and Smith A, "the merck index", 11th edn., Merk and co. İnc., New York, 1989, 669-670. Zaki M.T., and El-Didamony A.M., Analyst, (1988), 113, 1277-1281. Darweesh S. A. , Al-Haidari I. A. , Mohammed A.K. , Dikran S. B. , Spectrophotometric Determinations of Sulfacetamide Following Simple Diazotization and Coupling with Chromotropic Acid", Ibn Al-Haitham Jour. for Pure & Appl. Sci., 26 (3) 2013.
Birincil Dil en
Konular Mühendislik
Bölüm Makaleler
Yazarlar

Yazar: Zena TALAL
Kurum: Mosul University
Ülke: Iraq


Yazar: Wadala A. BASHIR
Kurum: Mosul University
Ülke: Iraq


Tarihler

Yayımlanma Tarihi : 24 Kasım 2019

Bibtex @araştırma makalesi { epstem679663, journal = {The Eurasia Proceedings of Science Technology Engineering and Mathematics}, issn = {}, eissn = {2602-3199}, address = {isresoffice@gmail.com}, publisher = {ISRES Organizasyon Turizm Eğitim Danışmanlık Ltd. Şti.}, year = {2019}, volume = {7}, pages = {385 - 390}, doi = {}, title = {Spectrophotometric Determination of Sulfacetamide}, key = {cite}, author = {TALAL, Zena and BASHIR, Wadala A.} }
APA TALAL, Z , BASHIR, W . (2019). Spectrophotometric Determination of Sulfacetamide. The Eurasia Proceedings of Science Technology Engineering and Mathematics , 7 () , 385-390 . Retrieved from https://dergipark.org.tr/tr/pub/epstem/issue/50288/679663
MLA TALAL, Z , BASHIR, W . "Spectrophotometric Determination of Sulfacetamide". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 385-390 <https://dergipark.org.tr/tr/pub/epstem/issue/50288/679663>
Chicago TALAL, Z , BASHIR, W . "Spectrophotometric Determination of Sulfacetamide". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 (2019 ): 385-390
RIS TY - JOUR T1 - Spectrophotometric Determination of Sulfacetamide AU - Zena TALAL , Wadala A. BASHIR Y1 - 2019 PY - 2019 N1 - DO - T2 - The Eurasia Proceedings of Science Technology Engineering and Mathematics JF - Journal JO - JOR SP - 385 EP - 390 VL - 7 IS - SN - -2602-3199 M3 - UR - Y2 - 2020 ER -
EndNote %0 The Eurasia Proceedings of Science Technology Engineering and Mathematics Spectrophotometric Determination of Sulfacetamide %A Zena TALAL , Wadala A. BASHIR %T Spectrophotometric Determination of Sulfacetamide %D 2019 %J The Eurasia Proceedings of Science Technology Engineering and Mathematics %P -2602-3199 %V 7 %N %R %U
ISNAD TALAL, Zena , BASHIR, Wadala A. . "Spectrophotometric Determination of Sulfacetamide". The Eurasia Proceedings of Science Technology Engineering and Mathematics 7 / (Kasım 2019): 385-390 .
AMA TALAL Z , BASHIR W . Spectrophotometric Determination of Sulfacetamide. EPSTEM. 2019; 7: 385-390.
Vancouver TALAL Z , BASHIR W . Spectrophotometric Determination of Sulfacetamide. The Eurasia Proceedings of Science Technology Engineering and Mathematics. 2019; 7: 390-385.