A Sublingual Neurofibroma: A Case Report

Yıl 2019, Cilt: 3 Sayı: 2, 109 - 114, 30.12.2019

Ahmet Altan , Aras Erdil , Nihat Akbulut

https://doi.org/10.35333/ERD.2019.103

Öz

Neurofibromatosis is a genetically inherited, autosomal dominant disorder. Deletions or mutations on chromosomes 17 and 22 precipitate to neurofibromatosis and there are genetically two types of the it as Type 1 and Type 2. Neurofibromatosis Type 1 is relevant with the abnormalities on chromosome 17.

In the affected population, the incidence of oral manifestation is as high as 92%, and the tongue is the most common involved site. Due to the lack of neurofibromin, which is encoded by the NF1 gene located on chromosome 17 and acts as a tumor suppressor protein, neurofibromas are frequently diagnosed on the tongue as
nodular growths or diffuse macroglossia in the oral cavity.

In this case report we aim to present our approach of treatment with intent to meet patient’s preprosthetic demands by performing an incisional biopsy on a sublingual neurofibroma and review the current literature in terms of diagnostic criteria, clinical features, accompanying impairments and treatment modalities.

Anahtar Kelimeler

sublingual, neurofibroma

Kaynakça

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