<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Erzincan University Journal of Science and Technology</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2149-4584</issn>
                                                                                            <publisher>
                    <publisher-name>Erzincan Binali Yıldırım Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.18185/erzifbed.1130305</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Engineering</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Mühendislik</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                                                            <article-title>Breast Tumor Detection and Classification Based on Microwave Imaging</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-8120-9679</contrib-id>
                                                                <name>
                                    <surname>Oral</surname>
                                    <given-names>Emin Argun</given-names>
                                </name>
                                                                    <aff>ATATURK UNIVERSITY, FACULTY OF ENGINEERING, DEPARTMENT OF ELECTRICAL AND ELECTRONICS ENGINEERING</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-3090-0328</contrib-id>
                                                                <name>
                                    <surname>Sahakian</surname>
                                    <given-names>Alan V.</given-names>
                                </name>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20220831">
                    <day>08</day>
                    <month>31</month>
                    <year>2022</year>
                </pub-date>
                                        <volume>15</volume>
                                        <issue>2</issue>
                                        <fpage>622</fpage>
                                        <lpage>635</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20220615">
                        <day>06</day>
                        <month>15</month>
                        <year>2022</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20220815">
                        <day>08</day>
                        <month>15</month>
                        <year>2022</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2008, Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi</copyright-statement>
                    <copyright-year>2008</copyright-year>
                    <copyright-holder>Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi</copyright-holder>
                </permissions>
            
                                                                                                                        <abstract><p>Limitations caused by traditional breast cancer detection and screening techniques have encouraged researchers to investigate alternative solutions.  This study examines the use of a microwave-based approach for tumor detection in breast tissue and related tumor type classification using matched-filtering. Radar-like confocal microwave imaging (CMI) method constructs the foundation of such tumor detection approach. In particular, a microwave pulse is first transmitted, then back-scattered pulses are collected. All major reflective sites in the breast tissue are detected by repeating this procedure on a microwave pulse transmission-reception grid, aligning captured signals in-time to focus on a particular region in the breast tissue and superimposing such time-shifted signals to improve signal-to-clutter level. In the observed signals, clutter is originated by the heterogeneity of the breast tissue while signal is originated by a tumor site as a function of its water content.All calculations, in the study, were performed computationally in terms of a 3D Finite-Difference Time-Domain (FDTD) simulation models. For the antenna system, two cross-polarized resistively loaded bow-ties antennas were used in the computational model, and the tumor site was modeled using five different size and morphologies. Matched-filtering, on the other hand, was performed matching such obtained observations with that of a homogenous breast tissue, namely clutter-free model. Performance of the proposed approach was tested for two different antenna array resolutions, and it was observed that this parameter is important for successful detection and classification of a tumor-site in a realistic heterogenous breast tissue model.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>confocal microwave imaging</kwd>
                                                    <kwd>  3D FDTD</kwd>
                                                    <kwd>  matched-filtering</kwd>
                                                    <kwd>  spherical tumor</kwd>
                                                    <kwd>  cylindrical tumor</kwd>
                                            </kwd-group>
                            
                                                                                                                                                    </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">American Cancer Society. Cancer Facts &amp; Figures 2021; American Cancer Society: Atlanta, GA, USA, 2021. Available online: https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2021.html (accessed on 21 April 2022)</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">S. Kwon, S. Lee, “Recent advances in microwave imaging for breast cancer detection”, Int. J. Biomed. Imaging. 2016, 5054912</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">S.G. Orel, M.D. Schnall, “MR imaging of the breast for the detection, diagnosis, and staging of breast cancer”, Radiology 2001, 220, 13–30</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">M.A. Aldhaeebi, T.S. Almoneef, H. Attia, O.M. Ramahi, “Near-Field Microwave Loop Array Sensor for Breast Tumor Detection”, IEEE Sens. J. 2019, 19, 11867-11872</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">B. Bocquet, J. Van de Velde, A. Mamouni, Y. Leroy, G. Giaux, J. Delannoy, D. Delvalee, “Microwave radiometric imaging at 3 GHz for the exploration of breast tumours”, IEEE Trans. Microw. Theory Tech. 1990, 38, 791–793</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">S. Mouty, B. Bocquet, R. Ringot, N. Rocourt, P. Devos, “Microwave radiometric imaging (MWI) for the characterisation of breast tumours”, Eur. Phys. J. Appl. Phys. 2000, 10, 73–78</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">P.M. Meaney, M.W. Fanning, D. Li, S.P. Poplack, K.D. Paulsen, “A clinical prototype for active microwave imaging of the breast”, IEEE Trans. Microw. Theory Tech. 2000, 48, 1841–1853</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">M. Ambrosanio, P. Kosmas, V. Pascazio, “A Multithreshold Iterative DBIM-Based Algorithm for the Imaging of Heterogeneous Breast Tissues”,  IEEE Trans. Biomed. Eng. 2018, 66, 509–520</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">M. Maffongelli, S. Poretti, A. Salvadè, R. Monleone, C. Pagnamenta, A. Fedeli,  M. Pastorino, A. Randazzo, “Design and experimental test of a microwave system for quantitative biomedical imaging”, Proceedings of the 2018 IEEE International Symposium on Medical Measurements and Applications (MeMeA), Rome, Italy, 11–13 June 2018; pp. 1–6</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">S.P. Rana, M. Dey, G. Tiberi, L. Sani, A. Vispa, G. Raspa, M. Duranti, M. Ghavami,  S. Dudley, “Machine Learning Approaches for Automated Lesion Detection in Microwave Breast Imaging”, Clinical Data. Sci. Rep. 2019, 9, 10510</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">O.M. Bucci, G. Bellizzi, A. Borgia, S. Costanzo, L. Crocco, G. Di Massa, R. Scapaticci, “Experimental framework for magnetic nanoparticles enhanced breast cancer microwave imaging”, IEEE Access 2017, 5, 16332–16340</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">S. C. Hagness, A. Taflove, J. E. Bridges, “Two-Dimensional FDTD Analysis of a pulsed Microwave Confocal System for Breast Cancer Detection: Fixed-Focus and Antenna-Array Sensors,” in IEEE Trans. On Biomed. Eng., vol. 45, no. 12, pp. 1470-1479, Dec. 1998</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">S. C. Hagness, A. Taflove, J. E. Bridges, “Three-Dimensional FDTD Analysis of a pulsed Microwave Confocal System for Breast Cancer Detection: Design of an Antenna-Array Element,” in IEEE Trans. On Antennas Propagat., vol. 47, no. 5, pp. 783-791, May 1999</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">X. Li, S. C. Hagness, “A Confocal Microwave Imaging Algorithm for Breast Cancer Detection,” in IEEE Microwave and Wireless Letters, vol. 11, no. 3, pp. 130-132, Mar. 2001</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">S. Coarsi, A. Massa, M. Pastorino, “Numerical Assessments Concerning a Focused Microwave Diagnostic Method for Medical Applications,” in IEEE Trans. On Microwave Theory and Tech., vol. 48, no. 11, pp. 1815-1830, Nov. 2000</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">K. R. Foster, and H. P. Schwan, “Dielectric properties of tissues and biological materials: A critical review,” Critical Reviews Biomed. Eng., vol. 17, no. 1, pp. 25-102, 1989</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">K. R. Foster, and J. L. Schepps, “Dielectric properties of tumor and normal tissues at radio through microwave frequencies,” Journal Microwave Power, vol. 16, no. 2, pp. 107-119, 1981</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">E. C. Fear, M. A. Stuchly, “Microwave Detection of Breast Cancer,” in IEEE Trans. On Microwave Theory and Tech., vol.48, no. 11, pp. 1854-1863, Nov. 2000</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">J. Shea, P. Kosmas, B. Van Veen, S. Hagness, “Contrast-enhanced microwave imaging of breast tumours: A computational study using 3D realistic numerical phantoms”, Inverse Probl. 2010, 26, 074009</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">D. Byrne, M. O’Halloran, M. Glavin, E. Jones, “Data independent radar beamforming algorithms for breast cancer detection”, Prog. Electromagn. Res. 2010, 107, 331–348</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">D. Byrne, M. Sarafianou, I.J. Craddock, “Compound radar approach for breast imaging”, IEEE Trans. Biomed. Eng. 2017, 64, 40–51</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">T. Yin, F.H. Ali, C.C. Reyes-Aldasoro, “A robust and artifact resistant algorithm of ultra-wideband imaging system for breast cancer detection”, IEEE Trans. Biomed. Eng. 2015, 62, 1514–1525</mixed-citation>
                    </ref>
                                    <ref id="ref23">
                        <label>23</label>
                        <mixed-citation publication-type="journal">S. Kubota, X. Xiao, N. Sasaki, Y. Kayaba, K. Kimoto, W. Moriyama, T. Kozaki,  M. Hanada, T. Kikkawa, “Confocal imaging using ultra wideband antenna array on Si substrates for breast cancer detection”, Jpn. J. Appl. Phys. 2010, 49, 097001</mixed-citation>
                    </ref>
                                    <ref id="ref24">
                        <label>24</label>
                        <mixed-citation publication-type="journal">I. Ünal, B. Türetken,  C. Canbay, “Spherical Conformal Bow-Tie Antenna for Ultra-Wide Band Microwave Imaging of Breast Cancer Tumour”, Appl. Comput. Electromagn. Soc. J. 2014, 29</mixed-citation>
                    </ref>
                                    <ref id="ref25">
                        <label>25</label>
                        <mixed-citation publication-type="journal">G.N. Bindu, S.J. Abraham, A. Lonappan, V. Thomas, C.K. Aanandan, K. Mathew, “Active microwave imaging for breast cancer detection”, Prog. Electromagn. Res. 2006, 58, 149–169</mixed-citation>
                    </ref>
                                    <ref id="ref26">
                        <label>26</label>
                        <mixed-citation publication-type="journal">E. C. Fear, X. Li, S. C. Hagness, M. A. Stuchly, “Confocal Microwave Imaging for Breast Cancer Detection: Localization of Tumors in Three Dimensions,” IEEE Trans. On Biomed. Eng., vol. 49, no. 8, pp. 812-822, Aug. 2002</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
