Yıl 2019, Cilt 20 , Sayı , Sayfalar 164 - 169 2019-12-16

World Health Organization projected the number of deaths due to cancer alone to be ~13.1 million by 2030. To a certain extent conventional chemotherapy has been successful, but poor bioavailability, high-dose requirements, adverse side effects, low therapeutic indices, development of multiple drug resistance, and non-specific targeting have been severe limitations to its success. These limitations can be overcome via “theranostics” as it is precision medicine providing simultaneous diagnosis, targeted treatment and monitoring. Here the major actor is the drug –the therapeutic compound. It is importance to develop new green chemistries and technologies to produce supramolecular nanomedicines by employing appropriate inorganic and organic structures as theranostic platforms. SrMoO4:Eu3+- MCM-41-ɣ-Fe2O3 composite was synthesized and characterized via FT-IR and XRD techniques. XRD pattern of SrMoO4:Eu3+- MCM-41-ɣ-Fe2O3 composite shows the presence of SrMoO4 (PDF card No: 01-075-4312), γ-Fe2O3 (PDF card no: 00-013-0458) and amorphous SiO2 structures. The drug loading was investigated via TG systems. The amount of Ibuprofen loaded in the drug loaded SrMoO4:Eu3+-MCM-41-ɣ-Fe2O3 microstructures, which were calculated from the TG curves, was found to be 14%. The release behavior of ibuprofen from SrMoO4:Eu3+- MCM-41-ɣ-Fe2O3-Ibu was investigated in the PBS solution at pH = 7.4 and at 37 oC for 66 h. In the first 8 h., Ibuprofen is released on the surface absorbed and clinging to weak interactions. After than, Slow release of ibuprofen attached to the pores was observed.
Theranostics, mesoporous ɣ-Fe2O3
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Birincil Dil en
Konular Temel Bilimler
Bölüm Makaleler
Yazarlar

Orcid: 0000-0003-1274-7905
Yazar: Ruken Esra DEMİRDÖĞEN (Sorumlu Yazar)
Kurum: ÇANKIRI KARATEKİN ÜNİVERSİTESİ
Ülke: Turkey


Orcid: 0000-0002-2018-0657
Yazar: Derya KILIÇ
Kurum: BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ, FEN-EDEBİYAT FAKÜLTESİ, KİMYA BÖLÜMÜ, KİMYA PR.
Ülke: Turkey


Orcid: 0000-0002-4974-2940
Yazar: Fatih Mehmet EMEN
Kurum: BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ, FEN-EDEBİYAT FAKÜLTESİ, KİMYA BÖLÜMÜ, KİMYA PR.
Ülke: Turkey


Orcid: 0000-0002-6680-3290
Yazar: Ali İhsan KARAÇOLAK
Kurum: BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ, FEN-EDEBİYAT FAKÜLTESİ, KİMYA BÖLÜMÜ, KİMYA PR.
Ülke: Turkey


Orcid: 0000-0002-8565-3136
Yazar: Muhammad Asım ALİ
Kurum: BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ, FEN-EDEBİYAT FAKÜLTESİ, KİMYA BÖLÜMÜ, KİMYA PR.
Ülke: Turkey


Orcid: 0000-0003-0211-1006
Yazar: Emine KUTLU
Kurum: BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ, FEN-EDEBİYAT FAKÜLTESİ, KİMYA BÖLÜMÜ, KİMYA PR.
Ülke: Turkey


Orcid: 0000-0003-0763-5802
Yazar: Tuncay YEŞİLKAYNAK
Kurum: KAHRAMANMARAS SUTCU IMAM UNIVERSITY, KAHRAMANMARAŞ VOCATIONAL SCHOOL
Ülke: Turkey


Orcid: 0000-0001-9423-3208
Yazar: Gokturk AVSAR
Kurum: MERSİN ÜNİVERSİTESİ
Ülke: Turkey


Destekleyen Kurum TÜBİTAK and Burdur Mehmet Akif Ersoy University coordinator of scientific research
Proje Numarası Project number of 116Z402, project number of 2017-YL-0472.
Tarihler

Yayımlanma Tarihi : 16 Aralık 2019

Bibtex @araştırma makalesi { estubtda656356, journal = {Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering}, issn = {2667-4211}, address = {btda@anadolu.edu.tr}, publisher = {Eskişehir Teknik Üniversitesi}, year = {2019}, volume = {20}, pages = {164 - 169}, doi = {10.18038/estubtda.656356}, title = {SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN}, key = {cite}, author = {Demi̇rdöğen, Ruken Esra and Kılıç, Derya and Emen, Fatih and Karaçolak, Ali and Ali̇, Muhammad and Kutlu, Emine and Yeşi̇lkaynak, Tuncay and Avsar, Gokturk} }
APA Demi̇rdöğen, R , Kılıç, D , Emen, F , Karaçolak, A , Ali̇, M , Kutlu, E , Yeşi̇lkaynak, T , Avsar, G . (2019). SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN . Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering , 20 () , 164-169 . DOI: 10.18038/estubtda.656356
MLA Demi̇rdöğen, R , Kılıç, D , Emen, F , Karaçolak, A , Ali̇, M , Kutlu, E , Yeşi̇lkaynak, T , Avsar, G . "SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN" . Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering 20 (2019 ): 164-169 <https://dergipark.org.tr/tr/pub/estubtda/issue/50600/656356>
Chicago Demi̇rdöğen, R , Kılıç, D , Emen, F , Karaçolak, A , Ali̇, M , Kutlu, E , Yeşi̇lkaynak, T , Avsar, G . "SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN". Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering 20 (2019 ): 164-169
RIS TY - JOUR T1 - SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN AU - Ruken Esra Demi̇rdöğen , Derya Kılıç , Fatih Emen , Ali Karaçolak , Muhammad Ali̇ , Emine Kutlu , Tuncay Yeşi̇lkaynak , Gokturk Avsar Y1 - 2019 PY - 2019 N1 - doi: 10.18038/estubtda.656356 DO - 10.18038/estubtda.656356 T2 - Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering JF - Journal JO - JOR SP - 164 EP - 169 VL - 20 IS - SN - 2667-4211- M3 - doi: 10.18038/estubtda.656356 UR - https://doi.org/10.18038/estubtda.656356 Y2 - 2019 ER -
EndNote %0 Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN %A Ruken Esra Demi̇rdöğen , Derya Kılıç , Fatih Emen , Ali Karaçolak , Muhammad Ali̇ , Emine Kutlu , Tuncay Yeşi̇lkaynak , Gokturk Avsar %T SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN %D 2019 %J Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering %P 2667-4211- %V 20 %N %R doi: 10.18038/estubtda.656356 %U 10.18038/estubtda.656356
ISNAD Demi̇rdöğen, Ruken Esra , Kılıç, Derya , Emen, Fatih , Karaçolak, Ali , Ali̇, Muhammad , Kutlu, Emine , Yeşi̇lkaynak, Tuncay , Avsar, Gokturk . "SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN". Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering 20 / (Aralık 2019): 164-169 . https://doi.org/10.18038/estubtda.656356
AMA Demi̇rdöğen R , Kılıç D , Emen F , Karaçolak A , Ali̇ M , Kutlu E , Yeşi̇lkaynak T , Avsar G . SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN. Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering. 2019; 20: 164-169.
Vancouver Demi̇rdöğen R , Kılıç D , Emen F , Karaçolak A , Ali̇ M , Kutlu E , Yeşi̇lkaynak T , Avsar G . SUPRAMOLECULARTHERANOSTIC PLATFORMS GOES GREEN. Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering. 2019; 20: 164-169.