etd Ege Tıp Dergisi 1016-9113 2147-6500 Ege Üniversitesi 10.19161/etd.458846 Health Care Administration Sağlık Kurumları Yönetimi Microbial colonization and antimicrobial susceptibility of the nose and external ear canal in hemodialysis patients Hemodiyaliz hastalarında dış kulak yolu ve nazal kavitede mikrobiyal kolonizasyon ve antimikrobiyal duyarlılık https://orcid.org/0000-0001-6048-034X Kılıç Korhan Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum https://orcid.org/0000-0002-4533-0308 Derman Eylül Atatürk University Faculty of Medicine, Department of Medical Microbiology, Erzurum https://orcid.org/0000-0001-9588-1725 Sakat Muhammed Sedat Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum https://orcid.org/0000-0002-9716-9579 Gözeler Mustafa Sıtkı Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum https://orcid.org/0000-0003-1478-7441 Uslu Hakan Atatürk University Faculty of Medicine, Department of Medical Microbiology, Erzurum https://orcid.org/0000-0001-9109-2681 Şengöz Furkan Atatürk University Faculty of Medicine, Department of Otorhinolaryngology, Erzurum 06 28 2019 58 2 126 130 01 05 2018 05 09 2018 Copyright © 1962, Ege Tıp Dergisi 1962 Ege Tıp Dergisi

Aim:The effect of normalbacterial flora on the immune system is to make it more effective againstharmful micro-organisms and to maintain it in readiness for a more rapidresponse. The purpose of this study was todetermine the bacterial flora in the external ear canal and nasal cavities inhemodialysis patients, to compare this with the normal population and to showthe microorganisms’ antibiotic susceptibilities. Materialsand Methods: Patients receiving hemodialysistherapy for at least 3 years were included in the study. A control group (n=62)was established consisting of patients with no immune-suppressive condition andpresenting to hospital with non-ear symptoms. Swab specimens were taken fromall subjects’ external ear canals and nasal cavities. Results of the cultureswere recorded and antimicrobial susceptibility test was performed.Results: The most commonly isolated micro-organisms in the study group wereMRCoNS (41%), followed by MSCoNS (15.5%) and diphtheroids (9.8%). Themicro-organism most commonly isolated from the nasal cavity in the study groupwas CoNS (52.7%), of which MRCoNS constituted 69.2%.Conclusion:We think that infections that play a major role inmortality and morbidity in hemodialysis patients may originate from theexternal ear canal as much as the nasal cavity, for this reason it is importantfor micro-organisms colonizing these regions to be eliminated with appropriatetreatment on the basis of antibiotic susceptibility tests.

Amaç: Normal bakteriyel floranınbağışıklık üzerindeki etkisi onu mikroorganizmaların zararlı etkilerine karşıdaha etkili hale getirmek ve hızlı bir cevap oluşturacak şekilde hazırtutmaktır. Bu çalışmanın amacı hemodiyaliz hastalarında nazal kavite ve dışkulak yolundaki bakteriyel florayı tespit etmek, bunu normal populasyonlakarşılaştırmak ve mikroorganizmaların antimikrobiyal duyarlılığını ortayakoymaktı. Gereç ve Yöntem: Çalışmaya en az 3 yıldırhemodiyaliz alan hastalar dâhil edildi. Herhangi bir immunsupresyon durumu olmayanve kulak hastalıkları dışı sebeplerle hastaneye başvuran hastalardan da kontrolgrubu oluşturuldu (n=62). Tüm katılımcıların nazal kavite ve dış kulakyollarından kültür çubuğu ile kültür örnekleri alındı. Kültür sonuçları ileantimikrobiyal duyarlılık test sonuçları kaydedildi. Bulgular: Çalışma grubunda dış kulakyolundan en çok izole edilen bakteri MRCoNS (%41) iken bunu MSCoNS (%15,5) veDifteroidler (%9,8) izlemekteydi. Nazal kaviteden ise en sık izole edilenbakteri CoNS olup (%52,7) bunun %69,2’sini MRCoNS oluşturmaktaydı. Sonuç: Hemodiyaliz hastalarındamortalite ve morbiditede önemli rol oynayan enfeksiyonların nazal kavite kadardış kulak yolundan da kaynaklanabileceğini, bu nedenle antimikrobiyalduyarlılık testleri ile belirlenen uygun antibiyoterapi ile bu bölgedekimikroorganizmaların da elimine edilmesinin önemli olduğunu düşünmekteyiz.

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