Research Article
BibTex RIS Cite
Year 2022, , 771 - 776, 04.11.2022
https://doi.org/10.18621/eurj.1090251

Abstract

References

  • 1. WHO Coronavirus (COVID-19) Dashboard. (https://covid19.who.int). Accessed 5 October 2021.
  • 2. Coronavirus. (https://www.who.int/westernpacific/health-topics/coronavirus). Accessed 23 July 2021.
  • 3. Izda V, Jeffries MA, Sawalha AH. COVID-19: a review of therapeutic strategies and vaccine candidates. Clin Immunol 2021;222:108634.
  • 4. Buitrago-Garcia D, Egli-Gany D, Counotte MJ, Hossmann S, Imeri H, Ipekci AM, et al. Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: a living systematic review and meta-analysis. PLoS Med 2020;17:e1003346.
  • 5. Sayampanathan AA, Heng CS, Pin PH, Pang J, Leong TY, Lee VJ. Infectivity of asymptomatic versus symptomatic COVID-19. Lancet 2021;397:93-4.
  • 6. Salzberger B, Buder F, Lampl B, Ehrenstein B, Hitzenbichler F, Holzmann T, et al. Epidemiology of SARS-CoV-2. Infection 2021;49:233-9.
  • 7. Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med 2020;382:970-1.
  • 8. Gao M, Yang L, Chen X, Deng Y, Yang S, Xu H, et al. A study on infectivity of asymptomatic SARS-CoV-2 carriers. Respir Med 2020;169:106026.
  • 9. Johansson MA, Quandelacy TM, Kada S, Prasad PV, Steele M, Brooks JT, et al. SARS-CoV-2 transmission from people without COVID-19 symptoms. JAMA Netw Open 2021;4:e2035057.
  • 10. Karbuz A, Akkoc G, Bedir Demirdag T, Yilmaz Ciftdogan D, Ozer A, Cakir D, et al. Epidemiological, clinical, and laboratory features of children with COVID-19 in Turkey. Front Pediatr 2021;9:172.
  • 11. Mantovani A, Rinaldi E, Zusi C, Beatrice G, Saccomani MD, Dalbeni A. Coronavirus disease 2019 (COVID-19) in children and/or adolescents: a meta-analysis. Pediatr Res 2021;89:733-7.
  • 12. Yasuhara J, Kuno T, Takagi H, Sumitomo N. Clinical characteristics of COVID-19 in children: a systematic review. Pediatr Pulmonol 2020;55:2565-75.
  • 13. Mehta NS, Mytton OT, Mullins EWS, Fowler TA, Falconer CL, Murphy OB, et al. SARS-CoV-2 (COVID-19): what do we know about children? A systematic review. Clin Infect Dis 2020;71:2469-79.
  • 14. Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics 2020;145:e20200702.
  • 15. Bhuiyan MU, Stiboy E, Hassan MZ, Chan M, Islam MS, Haider N, et al. Epidemiology of COVID-19 infection in young children under five years: a systematic review and meta-analysis. Vaccine 2021;39:667-77.
  • 16. Rostami A, Sepidarkish M, Leeflang MMG, Riahi SM, Nourollahpour Shiadeh M, Esfandyari S, et al. SARS-CoV-2 seroprevalence worldwide: a systematic review and meta-analysis. Clin Microbiol Infect 2021;27:331-40.
  • 17. García-Miguel FJ, Serrano-Aguilar PG, López-Bastida J. Preoperative assessment. Lancet 2003;362:1749-57.
  • 18. Struyf T, Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Leeflang MM, et al. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 disease. Cochrane Database Syst Rev 2020;2020:CD013665.
  • 19. Yong SEF, Anderson DE, Wei WE, Pang J, Chia WN, Tan CW, et al. Connecting clusters of COVID-19: an epidemiological and serological investigation. Lancet Infect Dis 2020;20:809-15.
  • 20. Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19. (https://www.idsociety.org/practice-guideline/covid-19-guideline-diagnostics/). Accessed 31 August 2021.
  • 21. Temaslı Takibi, Salgın Yönetimi, Evde Hasta İzlemi ve Filyasyon. (https://covid19.saglik.gov.tr/TR-66339/temasli-takibi-salgin-yonetimi-evde-hasta-izlemi-ve-filyasyon.html). Accessed 23 September 2021.
  • 22. Júnior VCP, Moura LFWG, Cavalcante RC, Lima JRC, Bezerra AS, Dantas DR de S, et al. Prevalence of COVID-19 in children, adolescents and adults in remote education situations in the city of Fortaleza, Brazil. Int J Infect Dis 2021;108:20-6.
  • 23. Healthcare Workers. (https://www.cdc.gov/coronavirus/2019-ncov/hcp/pediatric-hcp.html). Accessed 1 September 2021.
  • 24. Gudbjartsson DF, Helgason A, Jonsson H, Magnusson OT, Melsted P, Norddahl GL, et al. Spread of SARS-CoV-2 in the Icelandic population. N Eng J Med 2020;382:2302-15.
  • 25. Sutton D, Fuchs K, D’Alton M, Goffman D. Universal screening for SARS-CoV-2 in women admitted for delivery. N Eng J Med 2020;382:2163-4.
  • 26. Yu J, Ouyang W, Chua MLK, Xie C. SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China. JAMA Oncol 2020;6:1108-10.
  • 27. Patel AB, Clifford A, Creaden J, Kato K, Malakooti MR, Muller WJ, et al. Severe acute respiratory syndrome coronavirus 2 point prevalence among asymptomatic hospitalized children and subsequent healthcare worker evaluation. J Pediatr Infect Dis Soc 2020;9:617-9.
  • 28. Martins MM, Prata-Barbosa A, da Cunha AJLA. Update on SARS-CoV-2 infection in children. Paediatr Int Child Health 2021;41:56-64.
  • 29. Gao Y-D, Ding M, Dong X, Zhang J-J, Kursat Azkur A, Azkur D, et al. Risk factors for severe and critically ill COVID-19 patients: a review. Allergy 2021;76:428-55.
  • 30. Farinholt T, Doddapaneni H, Qin X, Menon V, Meng Q, Metcalf G, et al. Transmission event of SARS-CoV-2 delta variant reveals multiple vaccine breakthrough infections. BMC Med 2021:19:255.
  • 31. Haitao T, Vermunt JV, Abeykoon J, Ghamrawi R, Gunaratne M, Jayachandran M, et al. COVID-19 and sex differences. Mayo Clin Proc 2020;95:2189-203.
  • 32. Luo CH, Morris CP, Sachithanandham J, Amadi A, Gaston D, Li M, et al. Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant is associated with higher recovery of infectious virus compared to the alpha variant in both unvaccinated and vaccinated individuals. Clin Infect Dis 2022;75:e715-25.
  • 33. Alsohime F, Temsah M-H, Al-Nemri AM, Somily AM, Al-Subaie S. COVID-19 infection prevalence in pediatric population: etiology, clinical presentation, and outcome. J Infect Public Health 2020;13:1791-6.

Prevalence of asymptomatic SARS-CoV-2 infection in children in Sivas province, Central Anatolia

Year 2022, , 771 - 776, 04.11.2022
https://doi.org/10.18621/eurj.1090251

Abstract

Objectives: Transmission from asymptomatic patients is one of the biggest challenges in controlling the Coronavirus disease 2019 (COVID-19) outbreak because these cases are a potential source for disease spread. Based on this situation, the aim of our study is to determine the prevalence of COVID-19 in asymptomatic pediatric dental patients representing Sivas and surrounding provinces.


Methods:
The population of the study consists of pediatric patients between the ages of 0-14 who applied to Sivas Oral and Dental Health Hospital General Operating Room for dental treatments between July 2020 and August 2021.


Results:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was detected in only 5 patients (approximately 1.80%) out of 278 asymptomatic pediatric patients.


Conclusions:
It is thought that the COVID-19 infection, which threatens the whole world, can progress asymptomatically in children, and therefore it may be a risk factor for the spread of the infection. To tackle the COVID-19 pandemic, it is recommended to maintain a high level of infection control measures in schools and day-care and to implement widespread testing on a global scale targeting the pediatric population.

References

  • 1. WHO Coronavirus (COVID-19) Dashboard. (https://covid19.who.int). Accessed 5 October 2021.
  • 2. Coronavirus. (https://www.who.int/westernpacific/health-topics/coronavirus). Accessed 23 July 2021.
  • 3. Izda V, Jeffries MA, Sawalha AH. COVID-19: a review of therapeutic strategies and vaccine candidates. Clin Immunol 2021;222:108634.
  • 4. Buitrago-Garcia D, Egli-Gany D, Counotte MJ, Hossmann S, Imeri H, Ipekci AM, et al. Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: a living systematic review and meta-analysis. PLoS Med 2020;17:e1003346.
  • 5. Sayampanathan AA, Heng CS, Pin PH, Pang J, Leong TY, Lee VJ. Infectivity of asymptomatic versus symptomatic COVID-19. Lancet 2021;397:93-4.
  • 6. Salzberger B, Buder F, Lampl B, Ehrenstein B, Hitzenbichler F, Holzmann T, et al. Epidemiology of SARS-CoV-2. Infection 2021;49:233-9.
  • 7. Rothe C, Schunk M, Sothmann P, Bretzel G, Froeschl G, Wallrauch C, et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med 2020;382:970-1.
  • 8. Gao M, Yang L, Chen X, Deng Y, Yang S, Xu H, et al. A study on infectivity of asymptomatic SARS-CoV-2 carriers. Respir Med 2020;169:106026.
  • 9. Johansson MA, Quandelacy TM, Kada S, Prasad PV, Steele M, Brooks JT, et al. SARS-CoV-2 transmission from people without COVID-19 symptoms. JAMA Netw Open 2021;4:e2035057.
  • 10. Karbuz A, Akkoc G, Bedir Demirdag T, Yilmaz Ciftdogan D, Ozer A, Cakir D, et al. Epidemiological, clinical, and laboratory features of children with COVID-19 in Turkey. Front Pediatr 2021;9:172.
  • 11. Mantovani A, Rinaldi E, Zusi C, Beatrice G, Saccomani MD, Dalbeni A. Coronavirus disease 2019 (COVID-19) in children and/or adolescents: a meta-analysis. Pediatr Res 2021;89:733-7.
  • 12. Yasuhara J, Kuno T, Takagi H, Sumitomo N. Clinical characteristics of COVID-19 in children: a systematic review. Pediatr Pulmonol 2020;55:2565-75.
  • 13. Mehta NS, Mytton OT, Mullins EWS, Fowler TA, Falconer CL, Murphy OB, et al. SARS-CoV-2 (COVID-19): what do we know about children? A systematic review. Clin Infect Dis 2020;71:2469-79.
  • 14. Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics 2020;145:e20200702.
  • 15. Bhuiyan MU, Stiboy E, Hassan MZ, Chan M, Islam MS, Haider N, et al. Epidemiology of COVID-19 infection in young children under five years: a systematic review and meta-analysis. Vaccine 2021;39:667-77.
  • 16. Rostami A, Sepidarkish M, Leeflang MMG, Riahi SM, Nourollahpour Shiadeh M, Esfandyari S, et al. SARS-CoV-2 seroprevalence worldwide: a systematic review and meta-analysis. Clin Microbiol Infect 2021;27:331-40.
  • 17. García-Miguel FJ, Serrano-Aguilar PG, López-Bastida J. Preoperative assessment. Lancet 2003;362:1749-57.
  • 18. Struyf T, Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Leeflang MM, et al. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19 disease. Cochrane Database Syst Rev 2020;2020:CD013665.
  • 19. Yong SEF, Anderson DE, Wei WE, Pang J, Chia WN, Tan CW, et al. Connecting clusters of COVID-19: an epidemiological and serological investigation. Lancet Infect Dis 2020;20:809-15.
  • 20. Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19. (https://www.idsociety.org/practice-guideline/covid-19-guideline-diagnostics/). Accessed 31 August 2021.
  • 21. Temaslı Takibi, Salgın Yönetimi, Evde Hasta İzlemi ve Filyasyon. (https://covid19.saglik.gov.tr/TR-66339/temasli-takibi-salgin-yonetimi-evde-hasta-izlemi-ve-filyasyon.html). Accessed 23 September 2021.
  • 22. Júnior VCP, Moura LFWG, Cavalcante RC, Lima JRC, Bezerra AS, Dantas DR de S, et al. Prevalence of COVID-19 in children, adolescents and adults in remote education situations in the city of Fortaleza, Brazil. Int J Infect Dis 2021;108:20-6.
  • 23. Healthcare Workers. (https://www.cdc.gov/coronavirus/2019-ncov/hcp/pediatric-hcp.html). Accessed 1 September 2021.
  • 24. Gudbjartsson DF, Helgason A, Jonsson H, Magnusson OT, Melsted P, Norddahl GL, et al. Spread of SARS-CoV-2 in the Icelandic population. N Eng J Med 2020;382:2302-15.
  • 25. Sutton D, Fuchs K, D’Alton M, Goffman D. Universal screening for SARS-CoV-2 in women admitted for delivery. N Eng J Med 2020;382:2163-4.
  • 26. Yu J, Ouyang W, Chua MLK, Xie C. SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China. JAMA Oncol 2020;6:1108-10.
  • 27. Patel AB, Clifford A, Creaden J, Kato K, Malakooti MR, Muller WJ, et al. Severe acute respiratory syndrome coronavirus 2 point prevalence among asymptomatic hospitalized children and subsequent healthcare worker evaluation. J Pediatr Infect Dis Soc 2020;9:617-9.
  • 28. Martins MM, Prata-Barbosa A, da Cunha AJLA. Update on SARS-CoV-2 infection in children. Paediatr Int Child Health 2021;41:56-64.
  • 29. Gao Y-D, Ding M, Dong X, Zhang J-J, Kursat Azkur A, Azkur D, et al. Risk factors for severe and critically ill COVID-19 patients: a review. Allergy 2021;76:428-55.
  • 30. Farinholt T, Doddapaneni H, Qin X, Menon V, Meng Q, Metcalf G, et al. Transmission event of SARS-CoV-2 delta variant reveals multiple vaccine breakthrough infections. BMC Med 2021:19:255.
  • 31. Haitao T, Vermunt JV, Abeykoon J, Ghamrawi R, Gunaratne M, Jayachandran M, et al. COVID-19 and sex differences. Mayo Clin Proc 2020;95:2189-203.
  • 32. Luo CH, Morris CP, Sachithanandham J, Amadi A, Gaston D, Li M, et al. Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant is associated with higher recovery of infectious virus compared to the alpha variant in both unvaccinated and vaccinated individuals. Clin Infect Dis 2022;75:e715-25.
  • 33. Alsohime F, Temsah M-H, Al-Nemri AM, Somily AM, Al-Subaie S. COVID-19 infection prevalence in pediatric population: etiology, clinical presentation, and outcome. J Infect Public Health 2020;13:1791-6.
There are 33 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Articles
Authors

Merve Candan 0000-0002-9839-871X

Salih Yıldırım 0000-0002-4986-6812

Publication Date November 4, 2022
Submission Date March 19, 2022
Acceptance Date May 14, 2022
Published in Issue Year 2022

Cite

AMA Candan M, Yıldırım S. Prevalence of asymptomatic SARS-CoV-2 infection in children in Sivas province, Central Anatolia. Eur Res J. November 2022;8(6):771-776. doi:10.18621/eurj.1090251

e-ISSN: 2149-3189 


The European Research Journal, hosted by Turkish JournalPark ACADEMIC, is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

by-nc-nd.png

2025