Research Article

Renal artery stenosis: a single center experience

Volume: 9 Number: 6 November 4, 2023
EN

Renal artery stenosis: a single center experience

Abstract

Objectives: Renal artery stenosis (RAS) is among the most common causes of secondary hypertension. Prevalence of RAS are seen in end-stage renal disease (ESRD) patients with hypertension between 1-10%. In our study, we evaluated the data of patients with RAS who were followed up with medical treatment and stenting.

Methods: In our study, patients who were thought to have renal artery stenosis (RAS) with renal artery doppler ultrasonography were scanned with contrast-enhanced Magnetic Resonance Angiography (MRA). Fifty-three patients (10 received medical therapy, 43 applied invasive procedure) who diagnosed with RAS evaluated.

Results: Follow-up times were 15 (12-84) months in patients who received medical therapy, and 12 (10-96) months in patients who treated with invasive therapy (p = 0.583). Median ages were 56 (19-74) years in medical treatment group, and 60 (15-77) years in invasive therapy group (p = 0.955). Compared with the beginning of treatment, diastolic hypertension was decreased of 12.5% in invasive treatment group opposite medical therapy group (p = 0.040), so eGFR was increased of 5.94% in invasive treatment group.

Conclusions: In recent years, several studies about survival in patients with RAS was observed that there was no significant difference between the medical and invasive treatment. Clinical, laboratory, and individual characteristics should be considered in treatment choice.

Keywords

References

  1. 1. Bavishi C, de Leeuw PW, Messerli FH. Atherosclerotic renal artery stenosis and hypertension: pragmatism, pitfalls, and perspectives. Am J Med 2016;129:635.e5-14.
  2. 2. Safian RD, Textor SC. Renal-artery stenosis. N Engl J Med 2001;344:431-42.
  3. 3. Hansen KJ, Edwards MS, Craven TE, Cherr GS, Jackson SA, Appel RG, et al. Prevalence of renovascular disease in the elderly: a population-based study. J Vasc Surg 2002;36:443-51.
  4. 4. Textor SC. Managing renal arterial disease and hypertension. Curr Opin Cardiol 2003;18:260-7.
  5. 5. van Jaarsveld BC, Krijnen P, Pieterman H, Derkx FMH, Deinum J, Postma CT, et al. The effect of balloon angioplasty on hypertension in atherosclerotic renal-artery stenosis. N Engl J Med 2000;342:1007-14.
  6. 6. Haller C. Arteriosclerotic renal artery stenosis: conservative versus interventional management. Heart 2002;88:193-7.
  7. 7. Cooper CJ, Murphy TP, Cutlip DE, Jamerson K, Henrich W, Reid DM, et al. CORAL Investigators. Stenting and medical therapy for atherosclerotic renal-artery stenosis. N Engl J Med 2014;370:13-22.
  8. 8. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013;3:1-150.

Details

Primary Language

English

Subjects

​Internal Diseases

Journal Section

Research Article

Early Pub Date

June 1, 2023

Publication Date

November 4, 2023

Submission Date

May 20, 2022

Acceptance Date

November 22, 2022

Published in Issue

Year 1970 Volume: 9 Number: 6

AMA
1.Ayar Y, Döner B, Akgür S, İşleyen M, Ocakoğlu G. Renal artery stenosis: a single center experience. Eur Res J. 2023;9(6):1314-1320. doi:10.18621/eurj.1119037