Research Article

Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit

Volume: 9 Number: 2 March 4, 2023
EN

Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit

Abstract

Objectives: The need for an intensive care unit has increased during the pandemic of coronavirus disease (COVID-19). For this reason, intermediate-level intensive care units (IICUs) were established in hospitals worldwide. This study aims to evaluate the data of patients that hospitalized in IICU.

Methods: Patients under treatment for COVID-19 were followed up in IICU after the negative polymerized chain reaction test. A total of 52 patients were evaluated retrospectively between August 24, 2020 and March 1, 2021. The patients were divided into two groups according to discharge status from IICU (Group 1: exitus, Group 2: transferred to clinic, or discharged home). Demographic data, comorbidities, Acute Physiology and Chronic Health Evaluation II (APACHE II), Glasgow Coma Scale (GCS), treatments and procedures, and complications were recorded.

Results: Seventeen (32.7%) of 52 patients who were followed up in IICU died. Thirty-five patients (67.3%) were transferred to the clinic or discharged home. The APACHE II scores at admission to IICU were higher in Group 1 (26.11 ± 5.86) than in Group 2 (23.43 ± 6.32) but not statistically significant. GCS was statistically significantly lower in Group 1 than in Group 2 (7.82 ± 2.42 and 10.25 ± 2.58, respectively, p = 0.002). Mechanical ventilation rate (82.3%) and the need for inotropic agents (76.5%) were higher in Group 1 (p = 0,034 and p < 0.001, respectively). Tracheostomy was applied to 5 of all patients, and percutaneous endoscopic gastrostomy was performed 4 of them.

Conclusions: We think that IICU created during the pandemic provides effective treatment for patients needing intensive care. We think IICU is beneficial in providing quick patient discharge in tertiary intensive care units.

Keywords

Supporting Institution

Bursa Yüksek İhtisas Training and Research Hospital

Thanks

Thanks to intermediate level intensive care unit's multidiciplinary team for studying together and telling our hardwork with this trial during the pandemic.

References

  1. 1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020;382:727‐33.
  2. 2. Cucinotta D, Vanelli M. WHO declares COVID-19 a pandemic. Acta Biomed 2020;19;91:157-60.
  3. 3. Masa JF, Patout M, Scala R, Winck JC. Reorganizing the respiratory high dependency unit for pandemics. Expert Rev Respir Med 2021;15:1505-15.
  4. 4. T.C. Sağlık Bakanlığı Bilimsel Danışma Kurulu, COVID-19 (SARS-CoV-2 Enfeksiyonu) Ağır pnömoni, ARDS, Sepsis ve septik şok yönetimi. T.C.Sağlık Bakanlığı, 27 Mayıs 2021, Ankara. https://covid19.saglik.gov.tr/Eklenti/40781/0/covid19rehberiagirpnomoniardssepsisveseptiksokyontemipdf.pdf. Accessed May 30, 2021.
  5. 5. Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, et al. More than 50 long-term effects of COVID-19: a systematic review and meta-analysis. Sci Rep 2021;11:16144.
  6. 6. Carpagnano GE, Migliore G, Grasso S, Procacci V, Resta E, Panza F, Resta O. More skilled clinical management of COVID-19 patients modified mortality in an intermediate respiratory intensive care unit in Italy. Respir Res 2021;22:16.
  7. 7. Matute-Villacís M, Moisés J, Embid C, Armas J, Fernández I, Medina M, et al. Role of respiratory intermediate care units during the SARS-CoV-2 pandemic. BMC Pulm Med 2021;21:228.
  8. 8. Carrillo Hernandez-Rubio J, Sanchez-Carpintero Abad M, Yordi Leon A, Doblare Higuera G, Garcia Rodriguez L, Garcia Torrejon C, et al. Outcomes of an intermediate respiratory care unit in the COVID-19 pandemic. PLoS One 2020;15:e0243968.

Details

Primary Language

English

Subjects

Intensive Care

Journal Section

Research Article

Publication Date

March 4, 2023

Submission Date

September 29, 2022

Acceptance Date

December 2, 2022

Published in Issue

Year 2023 Volume: 9 Number: 2

APA
Ata, F., Yılmaz, C., Karaca, Ü., Özyaprak, B., Balkaya, A. N., Aytünür, C. S., & Onur, T. (2023). Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit. The European Research Journal, 9(2), 237-243. https://doi.org/10.18621/eurj.1181609
AMA
1.Ata F, Yılmaz C, Karaca Ü, et al. Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit. Eur Res J. 2023;9(2):237-243. doi:10.18621/eurj.1181609
Chicago
Ata, Filiz, Canan Yılmaz, Ümran Karaca, et al. 2023. “Evaluation of Patients With Negative PCR Tests After COVID-19 Pneumonia in Intermediate-Level Intensive Care Unit”. The European Research Journal 9 (2): 237-43. https://doi.org/10.18621/eurj.1181609.
EndNote
Ata F, Yılmaz C, Karaca Ü, Özyaprak B, Balkaya AN, Aytünür CS, Onur T (March 1, 2023) Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit. The European Research Journal 9 2 237–243.
IEEE
[1]F. Ata et al., “Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit”, Eur Res J, vol. 9, no. 2, pp. 237–243, Mar. 2023, doi: 10.18621/eurj.1181609.
ISNAD
Ata, Filiz - Yılmaz, Canan - Karaca, Ümran - Özyaprak, Buket - Balkaya, Ayşe Neslihan - Aytünür, Cihan Sedat - Onur, Tuğba. “Evaluation of Patients With Negative PCR Tests After COVID-19 Pneumonia in Intermediate-Level Intensive Care Unit”. The European Research Journal 9/2 (March 1, 2023): 237-243. https://doi.org/10.18621/eurj.1181609.
JAMA
1.Ata F, Yılmaz C, Karaca Ü, Özyaprak B, Balkaya AN, Aytünür CS, Onur T. Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit. Eur Res J. 2023;9:237–243.
MLA
Ata, Filiz, et al. “Evaluation of Patients With Negative PCR Tests After COVID-19 Pneumonia in Intermediate-Level Intensive Care Unit”. The European Research Journal, vol. 9, no. 2, Mar. 2023, pp. 237-43, doi:10.18621/eurj.1181609.
Vancouver
1.Filiz Ata, Canan Yılmaz, Ümran Karaca, Buket Özyaprak, Ayşe Neslihan Balkaya, Cihan Sedat Aytünür, Tuğba Onur. Evaluation of patients with negative PCR tests after COVID-19 pneumonia in intermediate-level intensive care unit. Eur Res J. 2023 Mar. 1;9(2):237-43. doi:10.18621/eurj.1181609