Case Report

Methemoglobinemia after local anesthesia with prilocaine in adults: four case reports

Volume: 10 Number: 2 March 4, 2024
EN

Methemoglobinemia after local anesthesia with prilocaine in adults: four case reports

Abstract

Methemoglobinemia is a serious hematological disease characterized by the incapability of sufficient oxygen delivery to tissues and cyanosis when iron within hemoglobin in ferrous form (Fe+2) is oxidized to ferric form (Fe+3). Methemoglobinemia may be congenital or acquired. While prilocaine-induced methemoglobinemia can be seen in newborns and early pediatric ages, it is a rare condition in adults. We aimed to investigate prilocaine-induced adult methemoglobinemia with four cases.

Keywords

References

  1. 1. Honig GR. Hemoglobin disorder. In: Behrman RE, Kleigman RM, Jenson HB, editors. Nelson Textbook of Pediatrics. 16th ed., WB Saunders Company: Philadelpiha. 2004: pp. 1478-1488.
  2. 2. Aygencel SG, Akinci E, Pamukcu G. Prilocaine induced methemoglobinemia. Saudi Med J. 2006;27(1):111-113.
  3. 3. Coleman MD, Coleman NA. Drug-induced methaemoglobinaemia. Treatment issues. Drug Saf. 1996;14(6):394-405. doi: 10.2165/00002018-199614060-00005.
  4. 4. Shibuya M, Hojo T, Hase Y, Kimura Y, Fujisawa T. Methemoglobinemia caused by a low dose of prilocaine during general anesthesia. J Dent Anesth Pain Med. 2021;21(4):357-361. doi: 10.17245/jdapm.2021.21.4.357.
  5. 5. Türkmen E, Kocabay G, Yavuz AS, Öztürk S. [A case of methemoglobinemia induced by the administratıon of prilocaine prior to an epilation procedure]. İst Tıp Fak. Derg. 2005;68(1):19-21. [Article in Turkish]
  6. 6. Balcı C, Koçoğulları C, Yılmaz M, Bayram E, Gürbüz S, Aydın U, et al. Prilokain Kullanımına Sekonder Gelişen Methemoglobinemi Olgusu (Poster). Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği 20. Ulusal kongresi 2014.
  7. 7. Caner İ, Ziraatçi Ö, Taştekin A. [Methemoglobinemia due to prilocaine which treated wıth oral methylene blue]. Türkiye Çocuk Hast Derg. 2011;5(3):172-176. [Article in Turkish]
  8. 8. Arslan MT, Arıca V, Tutanç M, Arıca SG. [Methemoglobinemia due to prilocaine administration]. Türk Pediatri Arşivi 2012;47(4):305-306. doi: 10.4274/tpa.308. [Article in Turkish]

Details

Primary Language

English

Subjects

Respiratory Diseases

Journal Section

Case Report

Early Pub Date

July 30, 2023

Publication Date

March 4, 2024

Submission Date

November 21, 2022

Acceptance Date

July 3, 2023

Published in Issue

Year 2024 Volume: 10 Number: 2

AMA
1.Yılmaz M, İşcan A, Mutlu L. Methemoglobinemia after local anesthesia with prilocaine in adults: four case reports. Eur Res J. 2024;10(2):249-253. doi:10.18621/eurj.1208264

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