Research Article

Relationship of breast arterial calcification and radiotherapy

Volume: 10 Number: 3 May 4, 2024
EN

Relationship of breast arterial calcification and radiotherapy

Abstract

Objective: The purpose of this research is to compare the pre and post-radiotherapy mammograms of patients who had breast-conserving surgery (BCS) and radiotherapy to see how radiotherapy affects breast arterial calcifications (BAC).

Methods: The study retrospectively compared the mammography examinations at least 24 months after radiotherapy and pre-radiotherapy mammography examinations of 123 female patients diagnosed with breast cancer and treated with BCS and radiotherapy between December 2001 and July 2011.

Results: Breast arterial calcifications (BAC) increased statistically significantly in 25 patients who underwent radiotherapy after BCS.

Conclusion: Our results indicate that BAC increases significantly after RT, especially in breasts treated with radiotherapy, with age being also a risk factor for BAC development.

Keywords

References

  1. 1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424. doi: 10.3322/caac.21492.
  2. 2. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin. 2019;69(1):7-34. doi: 10.3322/caac.21551.
  3. 3. Breast Cancer. National Comprehensive Cancer Network: National Clinical Practice Guidelines in Oncology. Version 3. 2018. https://www.nccn.org/ professionals/physician_gls/pdf/breast.pdf
  4. 4. Fisher B, Jeong JH, Anderson S, Bryant J, Fisher ER, Wolmark N. Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N Engl J Med. 2002;347(8):567-575. doi: 10.1056/NEJMoa020128.
  5. 5. Early Breast Cancer Trialists' Collaborative Group (EBCTCG); Darby S, McGale P, Correa C, et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011;378(9804):1707-1716. doi: 10.1016/S0140-6736(11)61629-2.
  6. 6. EBCTCG (Early Breast Cancer Trialists' Collaborative Group); McGale P, Taylor C, Correa C, et al. Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials. Lancet. 2014;383(9935):2127-2135. doi: 10.1016/S0140-6736(14)60488-8.
  7. 7. Grantzau T, Overgaard J. Risk of second non-breast cancer among patients treated with and without postoperative radiotherapy for primary breast cancer: a systematic review and meta-analysis of population-based studies including 522,739 patients. Radiother Oncol. 2016;121(3):402-413. doi: 10.1016/j.radonc.2016.08.017.
  8. 8. Boero IJ, Paravati AJ, Triplett DP, et al. Modern radiation therapy and cardiac outcomes in breast cancer. Int J Radiat Oncol Biol Phys. 2016;94(4):700-708. doi: 10.1016/j.ijrobp.2015.12.018.

Details

Primary Language

English

Subjects

Radiology and Organ Imaging

Journal Section

Research Article

Early Pub Date

December 29, 2023

Publication Date

May 4, 2024

Submission Date

October 28, 2023

Acceptance Date

November 28, 2023

Published in Issue

Year 2024 Volume: 10 Number: 3

APA
Karataş, G., Kula, O., & Tunçbilek, N. (2024). Relationship of breast arterial calcification and radiotherapy. The European Research Journal, 10(3), 268-275. https://doi.org/10.18621/eurj.1382545
AMA
1.Karataş G, Kula O, Tunçbilek N. Relationship of breast arterial calcification and radiotherapy. Eur Res J. 2024;10(3):268-275. doi:10.18621/eurj.1382545
Chicago
Karataş, Gökhan, Osman Kula, and Nermin Tunçbilek. 2024. “Relationship of Breast Arterial Calcification and Radiotherapy”. The European Research Journal 10 (3): 268-75. https://doi.org/10.18621/eurj.1382545.
EndNote
Karataş G, Kula O, Tunçbilek N (May 1, 2024) Relationship of breast arterial calcification and radiotherapy. The European Research Journal 10 3 268–275.
IEEE
[1]G. Karataş, O. Kula, and N. Tunçbilek, “Relationship of breast arterial calcification and radiotherapy”, Eur Res J, vol. 10, no. 3, pp. 268–275, May 2024, doi: 10.18621/eurj.1382545.
ISNAD
Karataş, Gökhan - Kula, Osman - Tunçbilek, Nermin. “Relationship of Breast Arterial Calcification and Radiotherapy”. The European Research Journal 10/3 (May 1, 2024): 268-275. https://doi.org/10.18621/eurj.1382545.
JAMA
1.Karataş G, Kula O, Tunçbilek N. Relationship of breast arterial calcification and radiotherapy. Eur Res J. 2024;10:268–275.
MLA
Karataş, Gökhan, et al. “Relationship of Breast Arterial Calcification and Radiotherapy”. The European Research Journal, vol. 10, no. 3, May 2024, pp. 268-75, doi:10.18621/eurj.1382545.
Vancouver
1.Gökhan Karataş, Osman Kula, Nermin Tunçbilek. Relationship of breast arterial calcification and radiotherapy. Eur Res J. 2024 May 1;10(3):268-75. doi:10.18621/eurj.1382545