Cardiac surgery in patients with essential thrombocytosis: a report of three cases
Abstract
Essential thrombocytosis has been classified as a chronic myeloproliferative disorder. Patients with essential thrombocytosis undergoing cardiac surgery are at increased risk for bleeding and thrombosis. However, the incidence and treatment for this condition are not well known. There are profound implications of essential thrombocytosis in patients undergoing cardiac surgery with the use of cardiopulmonary bypass, where heparin is used for anticoagulation. We want to present successful cardiac surgery in three patients with essential thrombocytosis. Patients received hydroxyurea and antiagregant treatment preoperatively and the thrombocyte counts were lowered to reference ranges. There were no cardiac or systemic complications due to essential thrombocytosis during the postoperative period.
Keywords
References
- Scholzel BE, Endeman H, Dewilde W, Yilmaz A, de Weerdt O, ten Berg JM. Cardiac surgery in a patient with essential thrombocythemia: a case report. Neth Heart J 2010;18:378-380.
- Ahmed K, Vohra HA, Milne A, Langley SM. Aortic valve replacement in a young patient with essential thrombocytosis. J Cardiothorac Surg 2008;3:5.
- Gutierrez-Martin MA, Araji OA, Miranda N, Barquero JM. Mitroaortic valve replacement after aortic transapical approach failure in a patient with essential thrombocytosis. Interact Cardiovasc Thorac Surg 2010;11:360-361.
- Wang DW, Zhang Y, Yao JM, Xiao ZB. Surgical treatment of a ventricular aneurysm in a patient with essential thrombocythemia complicated by acute myocardial infarction: A case report. Exp Ther Med 2014;7:267-269.
- Briere JB. Essential thrombocythemia. Orphanet J Rare Dis 2007;2:3.
- Kaya K, Cavolli R, Telli A, Tasoz R. Off-pump coronary artery surgery in a patient with essential thrombocythaemia: two life-threatening complications in the same patient. BMJ Case Rep 2009;2009:bcr01.2009.1503.
- Hawkins JL, Myers GJ, Legare JF, Swyer W. Arterial filter bypass loop: what occurs in this area during cardiopulmonary bypass and are there potential patient implications. J Extra Corpor Technol 2010;42:71-74.
- Dogan A, Dogan AL, Canpinar H, Demirpence E. The Effect of hydroxyurea on the microbicidal functions of leukocyte. Turk J Biochem 2004;29:232-236.
Details
Primary Language
English
Subjects
Cardiovascular Surgery
Journal Section
Case Report
Authors
Ufuk Aydin
Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Türkiye
Filiz Ata
This is me
Department of Anesthesiology, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Türkiye
Derih Ay
Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Türkiye
Yusuf Ata
This is me
Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Türkiye
Tamer Turk
Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Türkiye
Senol Yavuz
Department of Cardiovascular Surgery, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
0000-0001-5246-0808
Türkiye
Publication Date
July 4, 2016
Submission Date
March 30, 2016
Acceptance Date
April 18, 2016
Published in Issue
Year 2016 Volume: 2 Number: 2