The association between lipid profile and bone mineral density in subjects with ankylosing spondylitis

Yıl 2019, , 355 - 360, 04.03.2019

Betül Sargın Gülcan Gürer Hakan Öztürk

https://doi.org/10.18621/eurj.359518

Öz

Objective: This study aims to investigate the relationship between serum
lipids and bone mineral density in ankylosing spondylitis patients.

Methods: A total of 94 ankylosing spondylitis patients fulfilling the
1984 Modified New York Criteria who had serum lipid levels and bone mineral
density scores in medical records were included in this study. These patients
treated with nonsteroid antiinflammatory drugs. Their files were examined in
detail. Later demographic and laboratory features were recorded to the research
form. Dual-energy X-ray absorptiometry was used to assess bone mineral density
in two bone sites of femur (neck, intertrochanteric zone and trochanter) and
spinal lumbar vertebras (Lumbar 1-Lumbar 4).

Results: Significant and positive correlation was found between high
density lipoprotein and femoral neck bone mineral density (r = 0.356, p =
0.021) in osteopenic group and in osteoporotic group (r = 0.005, p =
0.040).

Conclusion: According to our study significant and positive correlations
are found between high density lipoprotein and femoral neck bone mineral density
in osteopenic and osteoporotic group. However, we believe that more studies are
needed about this research. 

Anahtar Kelimeler

Ankylosing spondylitis, lipid profile, bone mineral density

Kaynakça

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