Objective: Autosomal dominant polycystic kidney disease (ADPKD)
mainly affects the kidneys, but other abnormalities like intracranial aneurysms
(ICAs) are not uncommon. In this study, we aimed to investigate retrospectively
frequency of ICA and other neurological abnormalities in ADPKD patients.
Methods: One hundred and forty patients with ADPKD who did not receive replacement
therapy and followed-up at outpatient clinic were evaluated.
Results: The mean age of the patients was 43.4 ± 13 years and mean glomerular filtration
rate was 87 ± 15 ml/min. ICA was detected in four (2.8%) patients. Three patients were from the same family. Thirteen (9.3%)
patients had magnetic resonance angiography due to their family stories, but
aneurysm was not seen in them.
Conclusion: Individuals with ADPKD who
have a history of aneurysm or hemorrhage in their family should be screened for
aneurysm due to mortality and risk of recurrent rupture.
Autosomal dominant polycystic kidney disease intracranial aneurysms arachnoid cysts
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Original Article |
Yazarlar | |
Yayımlanma Tarihi | 4 Ocak 2019 |
Gönderilme Tarihi | 17 Ocak 2018 |
Kabul Tarihi | 12 Şubat 2018 |
Yayımlandığı Sayı | Yıl 2019 |