Unusual uterine metastasis of plasmablastic lenfoma: a case report
Abstract
Plasmablastic lenfoma (PBL) is a diffuse large B-cell lymphoma (DLBCL)’s variant form that is especially reported in HIV-infected patients. PBL is a rare entity seen most commonly in the setting of immunocompromise. However, this disease may present in extraoral sites in which the genital tract appears to be the less common. Here we present a patient with uterine and fallopian mass diagnosed PBL. A 51-year-old multipara (G6P4C2) woman with a chief complaint of irregular vaginal bleeding was presented to our outpatient clinic. She had a prior history of breast cancer treated by right mastectomy and adjuvant chemotherapy.Transvaginal ultrasonography and magnetic resonance imaging both showed an uterine mass thought to be leiomyoma, which 4×3 cm in size on the anterior wall of uterin corpus. The pathology result of the mass was found to be plasmablastic lymphoma. Genital involvement also appears to be last but possible site option to find PBL focus in immunocompetent patients.
Keywords
References
- [1] El Fakih R, Almahayni M, Alsermani M. Plasmablastic lymphoma presenting as exophytic skin lesions. Hematol Oncol Stem Cell Ther 2017;10:164-5.
- [2] Delecluse HJ, Anagnostopoulos I, Dallenbach F, Hummel M, Marafioti T, Schneider U, et al. Plasmablastic lymphomas of the oral cavity: a new entity associated with the human immunodeficiency virus infection. Blood 1997:15;89:1413-20.
- [3] Lee OJ, Kim KW, Lee GK. Epstein-Barr virus and human immunodeficiency virus-negative oral plasmablastic lymphoma. J Oral Pathol Med 2006;35:382-4.
- [4] Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 2016;127:2375-90.
- [5] Morton LM, Wang SS, Devesa SS, Hartge P, Weisenburger DD, Linet MS. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood 2006;107:265-76.
- [6] Dittus C, Sarosiek S. A case of HIV-negative plasmablastic lymphoma of the bone marrow with a unique immunophenotype. Clin Case Rep 2017;5:902-4.
- [7] Han X, Duan M, Hu L, Zhou D, Zhang W. Plasmablastic lymphoma: Review of 60 Chinese cases and prognosis analysis. Medicine (Baltimore) 2017;96:e5981.
- [8] Gong J, Alkan S, Anand S. A case of cutaneous plasmablastic lymphoma in HIV/AIDS with disseminated cryptococcus. Case Rep Oncol Med 2013;2013:862585.
Details
Primary Language
English
Subjects
Oncology and Carcinogenesis , Obstetrics and Gynaecology
Journal Section
Case Report
Authors
Suat Karataş
0000-0003-1592-0304
Türkiye
Tayfur Çift
0000-0003-4025-9343
Türkiye
Veysel Şal
This is me
0000-0002-5698-3734
Türkiye
Meltem Tekelioğlu
This is me
0000-0001-9107-8708
Türkiye
Özlem Ton
This is me
0000-0002-6499-7298
Türkiye
Publication Date
November 4, 2019
Submission Date
August 27, 2018
Acceptance Date
June 1, 2019
Published in Issue
Year 2019 Volume: 5 Number: 6