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Therapeutic approaches to language skills in major neurodegenerative disorders: a literature review

Year 2024, EARLY ONLINE, 1 - 6
https://doi.org/10.18621/eurj.1467080

Abstract

Major Neurodegenerative Disorders (MNDs) impact a large number of individuals globally. Individuals with neurodegenerative diseases have a significant problem due to the gradual development of communication difficulties. This is a review article to address the latest ways to manage and help individuals with language problems because of neurological diseases like Alzheimer's disease, mild cognitive impairment (MCI), and primary progressive aphasia (PPA). In the beginning we'll discuss the diseases, and then we'll be discussing how to treat them. The therapies used for Alzheimer's disease and PPA have been subject to extensive research. Therefore, the techniques follow a more structured way. However, there is a limited number of research in MCI and the strategies used in MCI mostly concentrate on enhancing the communication abilities of patients and their caregivers. There is a need for more research to increase approaches for speech and language therapy, as there is limited research on intervention in Turkish patients with MCI, PPA and Alzheimer's disease. It is critical to have evidence-based practice in MNDs, and more research is required to understand the effectiveness of speech and language therapy.

References

  • 1. Dugger BN, Dickson DW. Pathology of Neurodegenerative Diseases. Cold Spring Harb Perspect Biol. 2017;9(7):a028035. doi: 10.1101/cshperspect.a028035.
  • 2. Mesulam MM. Primary progressive aphasia. Ann Neurol. 2001;49(4):425-32. doi: 10.1002/ana.91.
  • 3. Boschi V, Catricalà E, Consonni M, Chesi C, Moro A, Cappa SF. Connected Speech in Neurodegenerative Language Disorders: A Review. Front Psychol. 2017;8:269. doi: 10.3389/fpsyg.2017.00269.
  • 4. Gauthier S, Reisberg B, Zaudig M, et al; International Psychogeriatric Association Expert Conference on mild cognitive impairment. Mild cognitive impairment. Lancet. 2006;367(9518):1262-1270. doi: 10.1016/S0140-6736(06)68542-5.
  • 5. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56(3):303-308. doi: 10.1001/archneur.56.3.303.
  • 6. Taler V, Phillips NA. Language performance in Alzheimer's disease and mild cognitive impairment: a comparative review. J Clin Exp Neuropsychol. 2008;30(5):501-556. doi: 10.1080/13803390701550128.
  • 7. McCullough KC, Bayles KA, Bouldin ED. Language Performance of Individuals at Risk for Mild Cognitive Impairment. J Speech Lang Hear Res. 2019;62(3):706-722. doi: 10.1044/2018_JSLHR-L-18-0232.
  • 8. Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7(3):270-279. doi: 10.1016/j.jalz.2011.03.008.
  • 9. Tsantali E, Economidis D, Tsolaki M. Could language deficits really differentiate Mild Cognitive Impairment (MCI) from mild Alzheimer's disease? Arch Gerontol Geriatr. 2013;57(3):263-270. doi: 10.1016/j.archger.2013.03.011.
  • 10. Weakley A, Schmitter-Edgecombe M, Anderson J. Analysis of verbal fluency ability in amnestic and non-amnestic mild cognitive impairment. Arch Clin Neuropsychol. 2013;28(7):721-731. doi: 10.1093/arclin/act058.
  • 11. Ahmed S, Arnold R, Thompson SA, Graham KS, Hodges JR. Naming of objects, faces and buildings in mild cognitive impairment. Cortex. 2008;44(6):746-752. doi: 10.1016/j.cortex.2007.02.002.
  • 12. Karalı FS, Maviş İ, Cinar N. Comparison of language and narrative features of individuals among amnestic mild cognitive impairment and healthy adults. Curr Psychol. 2023;42(29):25584-25593. doi: 10.1007/s12144-022-03669-9
  • 13. Banovic S, Zunic LJ, Sinanovic O. Communication Difficulties as a Result of Dementia. Mater Sociomed. 2018;30(3):221-224. doi: 10.5455/msm.2018.30.221-224.
  • 14. Bayles K, McCullough K, Tomoeda CK. Cognitive-Communication Disorders of MCI and Dementia: Definition, Assessment, and Clinical Management. 3rd ed., San Diago:Plural Publishing, 2018.
  • 15. Lanzi AM, Ellison JM, Cohen ML. The "Counseling+" Roles of the Speech-Language Pathologist Serving Older Adults With Mild Cognitive Impairment and Dementia From Alzheimer's Disease. Perspect ASHA Spec Interest Groups. 2021;6(5):987-1002. doi: 10.1044/2021_persp-20-00295.
  • 16. Greenaway MC, Duncan NL, Smith GE. The memory support system for mild cognitive impairment: randomized trial of a cognitive rehabilitation intervention. Int J Geriatr Psychiatry. 2013;28(4):402-409. doi: 10.1002/gps.3838.
  • 17. Pleasant M, Molinari V, Dobbs D, Meng H, Hyer K. Effectiveness of online dementia caregivers training programs: A systematic review. Geriatr Nurs. 2020;41(6):921-935. doi: 10.1016/j.gerinurse.2020.07.004.
  • 18. Bayles KA. Effects of working memory deficits on the communicative functioning of Alzheimer's dementia patients. J Commun Disord. 2003;36(3):209-219. doi: 10.1016/s0021-9924(03)00020-0.
  • 19. Bayles KA, Tomoeda CK, Trosset MW. Relation of linguistic communication abilities of Alzheimer's patients to stage of disease. Brain Lang. 1992;42(4):454-472. doi: 10.1016/0093-934x(92)90079-t.
  • 20. Bayles KA, Tomoeda CK, Cruz RF, Mahendra N. Communication abilities of individuals with late-stage Alzheimer disease. Alzheimer Dis Assoc Disord. 2000;14(3):176-181. doi: 10.1097/00002093-200007000-00009.
  • 21. Emery VO. Language impairment in dementia of the Alzheimer type: a hierarchical decline? Int J Psychiatry Med. 2000;30(2):145-164. doi: 10.2190/X09P-N7AU-UCHA-VW08.
  • 22. Kertesz A. Language deterioration in dementia. In Dementia: Presentations, Differential Diagnosis, and Nosology, 2nd ed.; NetLibrary, Incorporated Distributor; Johns Hopkins University Press: Baltimore, MD, USA; Boulder, CO, USA, 2004; pp. 108-122.
  • 23. Lekeu F, Van der Linden M, Chicherio C, et al. Brain correlates of performance in a free/cued recall task with semantic encoding in Alzheimer disease. Alzheimer Dis Assoc Disord. 2003;17(1):35-45. doi: 10.1097/00002093-200301000-00005.
  • 24. Macoir J, Turgeon Y. Dementia and language. In The Encyclopedia of Language and Linguistics, 2nd ed.; Elsevier Ltd.: Oxford, UK, 2006; pp. 423-430.
  • 25. Fisher NJ, Tierney MC, Rourke BP, Szalai JP. Verbal fluency patterns in two subgroups of patients with Alzheimer's disease. Clin Neuropsychol. 2004;18(1):122-131. doi: 10.1080/13854040490507235.
  • 26. Morello ANDC, Lima TM, Brandão L. Language and communication non-pharmacological interventions in patients with Alzheimer's disease: a systematic review. Communication intervention in Alzheimer. Dement Neuropsychol. 2017;11(3):227-241. doi: 10.1590/1980-57642016dn11-030004.
  • 27. Cavallo M, Hunter EM, van der Hiele K, Angilletta C. Computerized Structured Cognitive Training in Patients Affected by Early-Stage Alzheimer's Disease is Feasible and Effective: A Randomized Controlled Study. Arch Clin Neuropsychol. 2016;31(8):868-876. doi: 10.1093/arclin/acw072.
  • 28. Martínez-Moreno M, Cerulla N, Chico G, Quintana M, Garolera M. Comparison of neuropsychological and functional outcomes in Alzheimer's disease patients with good or bad response to a cognitive stimulation treatment: a retrospective analysis. Int Psychogeriatr. 2016;28(11):1821-1833. doi: 10.1017/S104161021600123X.
  • 29. Nousia A, Siokas V, Aretouli E, et al. Beneficial Effect of Multidomain Cognitive Training on the Neuropsychological Performance of Patients with Early-Stage Alzheimer's Disease. Neural Plast. 2018;2018:2845176. doi: 10.1155/2018/2845176.
  • 30. Parlak MM, Köse A, Güç M, Munis ÖB. Development of mobile compatible software for cognitive-communication disorder in individuals with Alzheimer's disease. Int J Lang Commun Disord. 2024;59(1):234-254. doi: 10.1111/1460-6984.12941.
  • 31. Mesulam MM. Primary progressive aphasia--a language-based dementia. N Engl J Med. 2003;349(16):1535-1542. doi: 10.1056/NEJMra022435.
  • 32. Volkmer A, Rogalski E, Henry M, et al. Speech and language therapy approaches to managing primary progressive aphasia. Pract Neurol. 2020;20(2):154-161. doi: 10.1136/practneurol-2018-001921.
  • 33. Mesulam MM, Rogalski EJ, Wieneke C, Hurley RS, Geula C, Bigio EH, Thompson CK, Weintraub S. Primary progressive aphasia and the evolving neurology of the language network. Nat Rev Neurol. 2014;10(10):554-569. doi: 10.1038/nrneurol.2014.159.
  • 34. Gorno-Tempini ML, Dronkers NF, Rankin KP, et al. Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol. 2004;55(3):335-346. doi: 10.1002/ana.10825.
  • 35. Rohrer JD, Ridgway GR, Crutch SJ, et al. Progressive logopenic/phonological aphasia: erosion of the language network. Neuroimage. 2010;49(1):984-993. doi: 10.1016/j.neuroimage.2009.08.002.
  • 36. Amici S, Gorno-Tempini ML, Ogar JM, Dronkers NF, Miller BL. An overview on Primary Progressive Aphasia and its variants. Behav Neurol. 2006;17(2):77-87. doi: 10.1155/2006/260734.
  • 37. Ruggero L, Nickels L, Croot K. Quality of life in primary progressive aphasia: what do we know and what can we do next? Aphasiology, 2019;33(5), 498-519. Doi: 10.1080/02687038.2019.1568135.
  • 38. Wauters LD, Croot K, Dial HR, et al. Behavioral Treatment for Speech and Language in Primary Progressive Aphasia and Primary Progressive Apraxia of Speech: A Systematic Review. Neuropsychol Rev. 2023 Oct 4. doi: 10.1007/s11065-023-09607-1.
  • 39. Rogalski EJ, Khayum B. A Life Participation Approach to Primary Progressive Aphasia Intervention. Semin Speech Lang. 2018;39(3):284-296. doi: 10.1055/s-0038-1660786.
  • 40 Badarunisa MB, Sebastian D, Rangasayee RR, Kala, B. ICF-based analysis of communication disorders in dementia of Alzheimer's type. Dement Geriatr Cogn Dis Extra. 2015;5(3), 459-469. doi: 10.1159/000441183.
Year 2024, EARLY ONLINE, 1 - 6
https://doi.org/10.18621/eurj.1467080

Abstract

References

  • 1. Dugger BN, Dickson DW. Pathology of Neurodegenerative Diseases. Cold Spring Harb Perspect Biol. 2017;9(7):a028035. doi: 10.1101/cshperspect.a028035.
  • 2. Mesulam MM. Primary progressive aphasia. Ann Neurol. 2001;49(4):425-32. doi: 10.1002/ana.91.
  • 3. Boschi V, Catricalà E, Consonni M, Chesi C, Moro A, Cappa SF. Connected Speech in Neurodegenerative Language Disorders: A Review. Front Psychol. 2017;8:269. doi: 10.3389/fpsyg.2017.00269.
  • 4. Gauthier S, Reisberg B, Zaudig M, et al; International Psychogeriatric Association Expert Conference on mild cognitive impairment. Mild cognitive impairment. Lancet. 2006;367(9518):1262-1270. doi: 10.1016/S0140-6736(06)68542-5.
  • 5. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol. 1999;56(3):303-308. doi: 10.1001/archneur.56.3.303.
  • 6. Taler V, Phillips NA. Language performance in Alzheimer's disease and mild cognitive impairment: a comparative review. J Clin Exp Neuropsychol. 2008;30(5):501-556. doi: 10.1080/13803390701550128.
  • 7. McCullough KC, Bayles KA, Bouldin ED. Language Performance of Individuals at Risk for Mild Cognitive Impairment. J Speech Lang Hear Res. 2019;62(3):706-722. doi: 10.1044/2018_JSLHR-L-18-0232.
  • 8. Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7(3):270-279. doi: 10.1016/j.jalz.2011.03.008.
  • 9. Tsantali E, Economidis D, Tsolaki M. Could language deficits really differentiate Mild Cognitive Impairment (MCI) from mild Alzheimer's disease? Arch Gerontol Geriatr. 2013;57(3):263-270. doi: 10.1016/j.archger.2013.03.011.
  • 10. Weakley A, Schmitter-Edgecombe M, Anderson J. Analysis of verbal fluency ability in amnestic and non-amnestic mild cognitive impairment. Arch Clin Neuropsychol. 2013;28(7):721-731. doi: 10.1093/arclin/act058.
  • 11. Ahmed S, Arnold R, Thompson SA, Graham KS, Hodges JR. Naming of objects, faces and buildings in mild cognitive impairment. Cortex. 2008;44(6):746-752. doi: 10.1016/j.cortex.2007.02.002.
  • 12. Karalı FS, Maviş İ, Cinar N. Comparison of language and narrative features of individuals among amnestic mild cognitive impairment and healthy adults. Curr Psychol. 2023;42(29):25584-25593. doi: 10.1007/s12144-022-03669-9
  • 13. Banovic S, Zunic LJ, Sinanovic O. Communication Difficulties as a Result of Dementia. Mater Sociomed. 2018;30(3):221-224. doi: 10.5455/msm.2018.30.221-224.
  • 14. Bayles K, McCullough K, Tomoeda CK. Cognitive-Communication Disorders of MCI and Dementia: Definition, Assessment, and Clinical Management. 3rd ed., San Diago:Plural Publishing, 2018.
  • 15. Lanzi AM, Ellison JM, Cohen ML. The "Counseling+" Roles of the Speech-Language Pathologist Serving Older Adults With Mild Cognitive Impairment and Dementia From Alzheimer's Disease. Perspect ASHA Spec Interest Groups. 2021;6(5):987-1002. doi: 10.1044/2021_persp-20-00295.
  • 16. Greenaway MC, Duncan NL, Smith GE. The memory support system for mild cognitive impairment: randomized trial of a cognitive rehabilitation intervention. Int J Geriatr Psychiatry. 2013;28(4):402-409. doi: 10.1002/gps.3838.
  • 17. Pleasant M, Molinari V, Dobbs D, Meng H, Hyer K. Effectiveness of online dementia caregivers training programs: A systematic review. Geriatr Nurs. 2020;41(6):921-935. doi: 10.1016/j.gerinurse.2020.07.004.
  • 18. Bayles KA. Effects of working memory deficits on the communicative functioning of Alzheimer's dementia patients. J Commun Disord. 2003;36(3):209-219. doi: 10.1016/s0021-9924(03)00020-0.
  • 19. Bayles KA, Tomoeda CK, Trosset MW. Relation of linguistic communication abilities of Alzheimer's patients to stage of disease. Brain Lang. 1992;42(4):454-472. doi: 10.1016/0093-934x(92)90079-t.
  • 20. Bayles KA, Tomoeda CK, Cruz RF, Mahendra N. Communication abilities of individuals with late-stage Alzheimer disease. Alzheimer Dis Assoc Disord. 2000;14(3):176-181. doi: 10.1097/00002093-200007000-00009.
  • 21. Emery VO. Language impairment in dementia of the Alzheimer type: a hierarchical decline? Int J Psychiatry Med. 2000;30(2):145-164. doi: 10.2190/X09P-N7AU-UCHA-VW08.
  • 22. Kertesz A. Language deterioration in dementia. In Dementia: Presentations, Differential Diagnosis, and Nosology, 2nd ed.; NetLibrary, Incorporated Distributor; Johns Hopkins University Press: Baltimore, MD, USA; Boulder, CO, USA, 2004; pp. 108-122.
  • 23. Lekeu F, Van der Linden M, Chicherio C, et al. Brain correlates of performance in a free/cued recall task with semantic encoding in Alzheimer disease. Alzheimer Dis Assoc Disord. 2003;17(1):35-45. doi: 10.1097/00002093-200301000-00005.
  • 24. Macoir J, Turgeon Y. Dementia and language. In The Encyclopedia of Language and Linguistics, 2nd ed.; Elsevier Ltd.: Oxford, UK, 2006; pp. 423-430.
  • 25. Fisher NJ, Tierney MC, Rourke BP, Szalai JP. Verbal fluency patterns in two subgroups of patients with Alzheimer's disease. Clin Neuropsychol. 2004;18(1):122-131. doi: 10.1080/13854040490507235.
  • 26. Morello ANDC, Lima TM, Brandão L. Language and communication non-pharmacological interventions in patients with Alzheimer's disease: a systematic review. Communication intervention in Alzheimer. Dement Neuropsychol. 2017;11(3):227-241. doi: 10.1590/1980-57642016dn11-030004.
  • 27. Cavallo M, Hunter EM, van der Hiele K, Angilletta C. Computerized Structured Cognitive Training in Patients Affected by Early-Stage Alzheimer's Disease is Feasible and Effective: A Randomized Controlled Study. Arch Clin Neuropsychol. 2016;31(8):868-876. doi: 10.1093/arclin/acw072.
  • 28. Martínez-Moreno M, Cerulla N, Chico G, Quintana M, Garolera M. Comparison of neuropsychological and functional outcomes in Alzheimer's disease patients with good or bad response to a cognitive stimulation treatment: a retrospective analysis. Int Psychogeriatr. 2016;28(11):1821-1833. doi: 10.1017/S104161021600123X.
  • 29. Nousia A, Siokas V, Aretouli E, et al. Beneficial Effect of Multidomain Cognitive Training on the Neuropsychological Performance of Patients with Early-Stage Alzheimer's Disease. Neural Plast. 2018;2018:2845176. doi: 10.1155/2018/2845176.
  • 30. Parlak MM, Köse A, Güç M, Munis ÖB. Development of mobile compatible software for cognitive-communication disorder in individuals with Alzheimer's disease. Int J Lang Commun Disord. 2024;59(1):234-254. doi: 10.1111/1460-6984.12941.
  • 31. Mesulam MM. Primary progressive aphasia--a language-based dementia. N Engl J Med. 2003;349(16):1535-1542. doi: 10.1056/NEJMra022435.
  • 32. Volkmer A, Rogalski E, Henry M, et al. Speech and language therapy approaches to managing primary progressive aphasia. Pract Neurol. 2020;20(2):154-161. doi: 10.1136/practneurol-2018-001921.
  • 33. Mesulam MM, Rogalski EJ, Wieneke C, Hurley RS, Geula C, Bigio EH, Thompson CK, Weintraub S. Primary progressive aphasia and the evolving neurology of the language network. Nat Rev Neurol. 2014;10(10):554-569. doi: 10.1038/nrneurol.2014.159.
  • 34. Gorno-Tempini ML, Dronkers NF, Rankin KP, et al. Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol. 2004;55(3):335-346. doi: 10.1002/ana.10825.
  • 35. Rohrer JD, Ridgway GR, Crutch SJ, et al. Progressive logopenic/phonological aphasia: erosion of the language network. Neuroimage. 2010;49(1):984-993. doi: 10.1016/j.neuroimage.2009.08.002.
  • 36. Amici S, Gorno-Tempini ML, Ogar JM, Dronkers NF, Miller BL. An overview on Primary Progressive Aphasia and its variants. Behav Neurol. 2006;17(2):77-87. doi: 10.1155/2006/260734.
  • 37. Ruggero L, Nickels L, Croot K. Quality of life in primary progressive aphasia: what do we know and what can we do next? Aphasiology, 2019;33(5), 498-519. Doi: 10.1080/02687038.2019.1568135.
  • 38. Wauters LD, Croot K, Dial HR, et al. Behavioral Treatment for Speech and Language in Primary Progressive Aphasia and Primary Progressive Apraxia of Speech: A Systematic Review. Neuropsychol Rev. 2023 Oct 4. doi: 10.1007/s11065-023-09607-1.
  • 39. Rogalski EJ, Khayum B. A Life Participation Approach to Primary Progressive Aphasia Intervention. Semin Speech Lang. 2018;39(3):284-296. doi: 10.1055/s-0038-1660786.
  • 40 Badarunisa MB, Sebastian D, Rangasayee RR, Kala, B. ICF-based analysis of communication disorders in dementia of Alzheimer's type. Dement Geriatr Cogn Dis Extra. 2015;5(3), 459-469. doi: 10.1159/000441183.
There are 40 citations in total.

Details

Primary Language English
Subjects Neurology and Neuromuscular Diseases, Rehabilitation
Journal Section Reviews
Authors

Fenise Selin Karalı 0000-0003-1513-9219

Samet Tosun 0000-0002-9604-7430

Nilgün Çınar 0000-0003-3868-3137

Early Pub Date July 27, 2024
Publication Date
Submission Date April 16, 2024
Acceptance Date July 17, 2024
Published in Issue Year 2024 EARLY ONLINE

Cite

AMA Karalı FS, Tosun S, Çınar N. Therapeutic approaches to language skills in major neurodegenerative disorders: a literature review. Eur Res J. Published online July 1, 2024:1-6. doi:10.18621/eurj.1467080

e-ISSN: 2149-3189 


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