Clinical value of neutrophil to lymphocyte ratio in the region of lower extremity deep venous thrombosis

Year 2017, Volume: 3 Issue: 1, 43 - 48, 04.03.2017

Engin Akgul , Nurhayat Bircan Gunduz Yumun , Ahmet Hakan Vural

https://doi.org/10.18621/eurj.2017.5000199818

Cited By: 2

Abstract

Objectives. Many
studies have demonstrated a significant association between cardiovascular
disease and neutrophil to lymphocyte ratio (NLR). To our knowledge, no study
has been reported in patients with deep venous thrombosis (DVT) which affecting
proximal or distal leg. In this study we analyzed proximal and distal DVT
according to the NLR. Methods. This retrospective study
was obtained from patients’ records of a tertiary university hospital between
May 2011 to January 2014. A total of 57 patients with the diagnosis of acute
primary DVT and 30 patients as control group included in the study. All of them
were confirmed with lower extremity venous duplex examinations. Of these, 37
examinations with the diagnosis of proximal DVT were compared to 20
examinations with distal DVT. The groups compared regarding to complete blood
counter values. Results. Mean eosinophil
level was higher in the distal DVT group (0.28±0.24 vs. 0.12±0.01, p=0.001), whereas median NLR were higher
in the proximal DVT group than the distal DVT group (3.5 [0.5-4.3] vs. 2.3 [1.2-9.7],
respectively; p=0.002). In addition, median
NLR, leukocyte and neutrophil counts were statistically lower in the control
group than the others (p=0.014, p=0.027 and p=0.004, respectively). Conclusion. NLR, an inexpensive and
easily measurable laboratory variable, was independently and significantly
associated with the presence and severity of DVT, especially acute proximal
DVT. 

Keywords

Deep venous thrombosis, neutrophil to lymphocyte ratio (NLR)

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