Human papillomavirus causing tonsillar hypertrophy in non-cancerous tonsil

Year 2017, Volume: 3 Issue: 3, 269 - 272, 04.11.2017

Satvinder Singh Bakshi , Ramiya Kaipuzha Surianarayanan Gopalakrishnan Govindarajan A

https://doi.org/10.18621/eurj.337348

Abstract

Human papillomavirus (HPV) is associated
with the development of most anogenital carcinomas, including cervical cancer
and, has more recently been suggested to be a risk factor for a subset of head
and neck squamous cell carcinoma. A 15-year-old female presented with complaints of chronically progressive
pain on swallowing. Examination revealed bilateral Grade III tonsillar
enlargement with multiple warty appearances over the surface of the tonsils. She
underwent tonsillectomy and histopathologic study revealed tonsillar crypts
lined by stratified squamous epithelium with focal koilocytic changes. Polymerase chain reaction study
detected HPV 11 DNA. The presence of HPV in the oral cavity and upper
respiratory tract mucosa is of great importance, since several studies have
demonstrated an association of HPV with a great variety of benign and malignant
lesions. A rare case of benign papillomatosis of the tonsil is presented in
this study. There is a need for long-term follow-up due to the possibility and risk
factors for malignant transformation. 

Keywords

Human papillomavirus, chronic tonsillitis, tonsillectomy, benign papillomatosis

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