Rivaroxaban-induced acute pancreatitis

Year 2019, Volume: 5 Issue: 3, 569 - 571, 04.05.2019

Özgür Sirkeci , Emel Erkuş Sirkeci , Belma Taşel

https://doi.org/10.18621/eurj.417972

Cited By: 2

Abstract

Rivaroxaban
is a direct factor Xa inhibitor and has been safely used since 2008. It is used
for the detection of atrial fibrillation and venous thromboembolism.
Pancreatitis is one of the rare but dangerous side effects of rivaroxaban. The
case of a 53-year-old female patient that developed in the third month of drug
usage was evaluated, and it was confirmed after a full analysis was conducted
that excluded all other factors, such as biliary calculus, alcohol usage, hypertriglyceridemia,
biochemical parameters, ultrasonography and computed tomography that the
patient’s condition was caused by the use of Rivaroxaban. The aim of this case presentation
is to indicate that awareness should be increased regarding the risks of using
the drug Rivaroxaban, as it could lead to drug-induced pancreatitis, even
though this is rare. 

Keywords

drug-induced pancreatitis, rivaroxaban, drug safety

References

• [1] Cappell MS. Acute pancreatitis: etiology, clinical presentation, diagnosis, and therapy. Med Clin North Am 2008;92:889-923.
• [2] Badalov N, Baradarian R, Iswara K, Li J, Steinberg W, Tenner S. Drug-induced acute pancreatitis:an evidence-based review. Clin Gastroenterol Hepatol 2007;5:648-61.
• [3] http://www.ehealthme.com/ds/xarelto/pancreatitis/
• [4] Tenner S. Drug induced acute pancreatitis: Does it exist? World J Gastroenterol 2014;20:16529-34.
• [5] Hung WY, Abreu Lanfranco O. Contemporary review of drug-induced pancreatitis: A different perspective. World J Gastrointest Pathophysiol 2014;5:405-15.