Objectives:
Cardiac rehabilitation is known to have positive effects on the inflammatory
processes. The neutrophil-to-lymphocyte ratio (NLR) and the
platelet-to-lymphocyte ratio (PLR) were found to be indicative of inflammation.
The purpose of this study is to determine the effects of cardiac rehabilitation
on the NLR and PLR ratios of ST elevation myocardial infarction (STEMI)
patients.
Methods: The study
includes 101 STEMI patients that
underwent primary percutaneous coronary intervention (PCI). The patients were randomized into two groups: the cardiac
rehabilitation group (CR group, n = 68), and the control group (n = 33). One
month after primary PCI, cardiac rehabilitation was applied to CR group with
cycle ergometer for 8 weeks (30 sessions). The NLR and PLR parameters were
calculated from the complete blood count results from before and after the
cardiac rehabilitation application for both groups.
Results: When the
baseline values of the two groups were evaluated, the hemoglobin value of the
control group (13.10 ± 1.52 g/dL vs. 13.79 ± 1.26 g/dL; p = 0.03) and the PLR value of the CR group (122.50 ± 43.89 vs.
92.41 ± 23.70; p = 0.001) were
significantly higher. The post-cardiac rehabilitation complete blood count
parameters, and the NLR and PLR values were similar in both groups. The NLR
(3.11 ± 1.95 vs 2.39 ± 1.03; p =
0.003) and PLR (122.50 ± 43.89 vs. 108.68 ± 41.83; p = 0.025) parameters significantly decreased after the cardiac
rehabilitation application in the CR group, whereas there wasn't a change in
the control group.
Conclusion: It
was found that cardiac rehabilitation applied in STEMI patients caused a
significant decrease in NLR and PLR parameters, which are indicators of
inflammation.
cardiac rehabilitation myocardial infarction inflammation neutrophil-to-lymphocyte ratio platelet-to-lymphocyte ratio
Birincil Dil | İngilizce |
---|---|
Konular | Kalp ve Damar Cerrahisi |
Bölüm | Original Article |
Yazarlar | |
Yayımlanma Tarihi | 4 Kasım 2019 |
Gönderilme Tarihi | 23 Temmuz 2018 |
Kabul Tarihi | 25 Temmuz 2018 |
Yayımlandığı Sayı | Yıl 2019 Cilt: 5 Sayı: 6 |